Browse our CCR7 Proteins (CCR7)

Full name:
Chemokine (C-C Motif) Receptor 7 Proteins (CCR7)
On www.antibodies-online.com are 5 Chemokine (C-C Motif) Receptor 7 (CCR7) Proteins from 4 different suppliers available. Additionally we are shipping CCR7 Antibodies (287) and CCR7 Kits (27) and many more products for this protein. A total of 322 CCR7 products are currently listed.
Synonyms:
BLR2, ccr7-a, CD197, CDw197, CMKBR7, EBI1, Ebi1h, zgc:165629
list all proteins Gene Name GeneID UniProt
CCR7 12775 P47774
CCR7 1236 P32248
CCR7 287673  

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CCR7 Proteins (CCR7) by Origin

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More Proteins for CCR7 Interaction Partners

Zebrafish Chemokine (C-C Motif) Receptor 7 (CCR7) interaction partners

  1. Ccr7 functions during axis formation as a GPCR to inhibit beta-catenin (show CTNNB1 Proteins), likely by promoting Ca(2 (show CA2 Proteins)+) transients throughout the blastula.

Mouse (Murine) Chemokine (C-C Motif) Receptor 7 (CCR7) interaction partners

  1. CCR7 overexpression and RelB (show RELB Proteins) knockdown (KD) in imDCs improve skin-graft survival in a murine skin-transplantation model. Transfection with Ad-CCR7 and RelB (show RELB Proteins) KD in imDCs may be an effective approach inducing immune tolerance, thus being potentially valuable for inhibiting allograft rejection.

  2. data point to Ccr7 as a critical host defense restriction factor limiting neuroinflammation during acute West Nile virus infection

  3. The results suggest that CCR7 plays a causal role in maintaining innate and adaptive immunity in obesity.

  4. these data indicate that CCR7 and BTLA (show BTLA Proteins) cooverexpression imparts an intermediate immune phenotype in mmature dendritic cells when compared to that in CCR7- or BTLA (show BTLA Proteins)-expressing counterparts that show a more immunocompetent or immunotolerant phenotype

  5. Results suggest that baicalin exerts an inhibitory effect on airway inflammation, and this effect may be associated with the inhibition of CCR7 and its ligands, CCL19 (show CCL19 Proteins) and CCL21 (show CCL21 Proteins), as well as on the nuclear factor-Kappa B (NF-kappaB (show NFKB1 Proteins)) pathway in a mouse model of asthma.

  6. This study reveals a role for CCR7 in limiting Treg recirculation back to the thymus and enables separation of the mechanisms controlling Treg production and thymic recirculation.

  7. data reveal that CCR7 plays multifaceted roles in regulating collecting vessel permeability and fibrosis, with one of the key players being IRF4 (show IRF4 Proteins)-dependent DCs.

  8. the graft site microenvironment plays a critical role in alloimmunity by determining DC trafficking through the CCR7-CCL19 (show CCL19 Proteins)/21 axis.

  9. Comprehensive Survey of miRNA-mRNA Interactions Reveals That Ccr7 and Cd247 (CD3 zeta (show CD247 Proteins)) are Posttranscriptionally Controlled in Pancreas Infiltrating T Lymphocytes of Non-Obese Diabetic (NOD) Mice

  10. CD11b (show ITGAM Proteins) and CXCR4 (show CXCR4 Proteins) but not CCR7 have roles in neutrophil migration modulating lymph node lymphocyte proliferation in bacterial infections

Human Chemokine (C-C Motif) Receptor 7 (CCR7) interaction partners

  1. CCR7 expression levels in human tumors correlate with signatures of CD141 (show THBD Proteins)(+) DC, intratumoral T cells, and better clinical outcomes.

  2. specific role for CCL21/CCR7 in promoting EMT and metastasis in CD133+ pancreatic cancer stem-like cells

  3. This study showed that CCR7 are overexpressed in CD4 (show CD4 Proteins)(-) CD8 (show CD8A Proteins)(-) thymocytes of myasthenia gravis patients.

  4. High tumoral CCR7 expression correlated with potential lymphatic involvement and poor prognosis of metastatic renal cell carcinoma (show MOK Proteins) patients treated with tyrosine kinase (show TXK Proteins) inhibitors.

  5. Results show that upregulation of CCR7 promotes cell proliferation and inflammation in A549 non-small cell lung cancer cells. However, silencing of CCR7 via siRNA treatment promotes cell apoptosis and suppresses the inflammatory response and TGF-beta1 (show TGFB1 Proteins)-induced EMT (show ITK Proteins), which may be associated with NF-kappaB (show NFKB1 Proteins) signaling.

  6. Down-regulating CCR7 expression in MG63 cells could apparently inhibit cell proliferation, migration and invasion abilities of MG63 cells, and also induce cell apoptosis.

  7. These results suggest that upregulation of rat CCR7 expression does not change the phenotype, differentiation, or proliferation capacity of human adipose-derived stem cells (hASCs), but does enable efficient migration of hASCs to rat secondary lymphoid organs.

  8. CCL21 (show CCL21 Proteins)/CCR7 interaction contributes to the time-dependent proliferation of PTC (show F9 Proteins) cells by upregulating cyclin A (show CCNA2 Proteins), cyclin B1 (show CCNB1 Proteins) and cyclin-dependent kinase 1 (CDK1 (show CDK1 Proteins)) expression via the extracellular signal-regulated kinase (ERK (show EPHB2 Proteins)) pathway associated with iodine.

  9. we conclude that CCR7 gene locus harbours a polymorphism that modifies risk of MI in patients with Coronary artery disease (CAD). Replication of this association could be sought in a prospective cohort of initially healthy individuals

  10. this study shows that plasmacytoid dendritic cells from rheumatoid arthritis patients have high expression levels of CCR7

Cow (Bovine) Chemokine (C-C Motif) Receptor 7 (CCR7) interaction partners

  1. Fluorescent dye-labeled gammadelta T cells from afferent and efferent lymph lack CCR7 surface expression and display high levels of CD62L (show SELL Proteins) compared with CD4 (show CD4 Proteins) T cells, which do express CCR7.

  2. CCR7 transcripts were minimally expressed in ex vivo and proliferating WC1(+)gammadelta T cells, a unique cell population with proinflammatory characteristics

Pig (Porcine) Chemokine (C-C Motif) Receptor 7 (CCR7) interaction partners

  1. the pattern of expression of CCR7 in different populations of porcine lymphocytes appears to be similar to that of human, highlighting the value of the pig as a useful animal model for biomedical studies.

  2. Pre-translntation of sertli cell CCR7 significantly suppresses lymphocyte proliferation and prolongs allogeneic skin graft survival.

CCR7 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor.

Alternative names and synonyms associated with CCR7

  • chemokine (C-C motif) receptor 7 (ccr7)
  • chemokine (C-C motif) receptor 7 (CCR7)
  • chemokine (C-C motif) receptor 7 (LOC100338432)
  • chemokine (C-C motif) receptor 7 (Ccr7)
  • BLR2 protein
  • ccr7-a protein
  • CD197 protein
  • CDw197 protein
  • CMKBR7 protein
  • EBI1 protein
  • Ebi1h protein
  • zgc:165629 protein

Protein level used designations for CCR7

C-C chemokine receptor type 7 , zfCCR7 , CC chemokine receptor 7 , chemokine (C-C motif) receptor 7 a , chemokine (C-C motif) receptor 7 , c-C chemokine receptor type 7-like , C-C CKR-7 , CC-CKR-7 , CCR-7 , EBV-induced G-protein coupled receptor 1 , MIP-3 beta receptor , chemokine (C-C) receptor 7 , epstein-Barr virus-induced G-protein coupled receptor 1 , EBV-induced G protein-coupled receptor 1 , Epstein-Barr virus induced G-protein coupled receptor , Epstein-Barr virus induced gene 1 , lymphocyte-specific G protein-coupled peptide receptor , chemokine receptor 7

GENE ID SPECIES
565958 Danio rerio
574231 Macaca mulatta
100036961 Xenopus laevis
100338432 Oryctolagus cuniculus
100432347 Pongo abelii
12775 Mus musculus
1236 Homo sapiens
287673 Rattus norvegicus
510668 Bos taurus
491011 Canis lupus familiaris
428315 Gallus gallus
100728690 Cavia porcellus
396663 Sus scrofa
101109462 Ovis aries
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