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Browse our CD31 Proteins (PECAM1)

Full name:
Platelet/endothelial Cell Adhesion Molecule Proteins (PECAM1)
On www.antibodies-online.com are 37 Platelet/endothelial Cell Adhesion Molecule (PECAM1) Proteins from 12 different suppliers available. Additionally we are shipping CD31 Antibodies (1249) and CD31 Kits (76) and many more products for this protein. A total of 1382 CD31 products are currently listed.
Synonyms:
C85791, Cd31, CD31/EndoCAM, endoCAM, GPIIA', PECA1, Pecam, PECAM-1
list all proteins Gene Name GeneID UniProt
PECAM1 5175 P16284
PECAM1 18613 Q08481
PECAM1 29583 Q3SWT0

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CD31 Proteins (PECAM1) by Origin

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Top referenced CD31 Proteins

  1. Human CD31 Protein expressed in Human Cells - ABIN2002172 : Newman, Berndt, Gorski, White, Lyman, Paddock, Muller: PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily. in Science (New York, N.Y.) 1990 (PubMed)
    Show all 5 references for ABIN2002172

  2. Human CD31 Protein expressed in Human Cells - ABIN2002174 : Sun, Williams, Yan, Amin, Albelda, DeLisser et al.: Platelet endothelial cell adhesion molecule-1 (PECAM-1) homophilic adhesion is mediated by immunoglobulin-like domains 1 and 2 and depends on the cytoplasmic domain and the level of surface ... in The Journal of biological chemistry 1996 (PubMed)
    Show all 5 references for ABIN2002174

  3. Mouse (Murine) CD31 Protein expressed in Human Cells - ABIN2007760 : Newton-Nash, Newman: A new role for platelet-endothelial cell adhesion molecule-1 (CD31): inhibition of TCR-mediated signal transduction. in Journal of immunology (Baltimore, Md. : 1950) 1999 (PubMed)
    Show all 5 references for ABIN2007760

More Proteins for CD31 Interaction Partners

Cow (Bovine) Platelet/endothelial Cell Adhesion Molecule (PECAM1) interaction partners

  1. novel pathway for PECAM-1 regulation

  2. PECAM-1 may not function as a major mechanoreceptor for activation of MAPK (show MAPK1 Proteins) and AKT (show AKT1 Proteins) in ECs and that there are likely to be other mechanoreceptors in ECs functioning to detect shear stress and trigger intercellular signals.

  3. PECAM-1 and Fyn (show FYN Proteins) are essential components of a PECAM-1-based mechanosensory complex in endothelial cells

  4. PECAM-1 plays a role in the early pathogenesis of thrombotic meningoencephalitis.

Human Platelet/endothelial Cell Adhesion Molecule (PECAM1) interaction partners

  1. these data suggest that a sialic acid-containing glycan emanating from Asn-25 reinforces dynamic endothelial cell-cell interactions by stabilizing the PECAM-1 homophilic binding interface.

  2. Decreased FoxP3 (show FOXP3 Proteins) expression in CD31 (show HBA1 Proteins)(+) Tr cells.

  3. These results suggested that PECAM-1 could mediate platelet adhesion to endothelial cells under shear stress. Platelets binding to endothelial cells interfered with endothelial cell mechanotransduction through PECAM-1, affecting endothelial cell inflammatory responses towards pathological shear flow.

  4. Immunohistochemical expression of CD31 and vascular endothelial growth factor (VEGF) were assessed in parallel.

  5. CD31 (show HBA1 Proteins) is expressed in mycosis fungoides (MF) skin biopsies, which provides new evidence for the role of angiogenesis in the progression of MF

  6. The Leu125Val polymorphism of PECAM-1 and the level of soluble PECAM-1 are not associated with diabetic nephropathy in Caucasians with type 2 diabetes mellitus.

  7. We provide the first report that pro-angiogenic genes PECAM1, PTGS1 (show PTGS1 Proteins), FGD5 (show FGD5 Proteins), and MCAM (show MCAM Proteins) may play a vital role in pathological dermal angiogenesis disorders of psoriasis.

  8. The PECAM-1 functions as an adhesive stress-response protein to both maintain endothelial cell junctional integrity and speed restoration of the vascular permeability barrier following inflammatory or thrombotic challenge.

  9. These studies indicate a role for PECAM-1 in enhancing the inhibitory functions of TGF-beta (show TGFB1 Proteins) in T cells

  10. PECAM1 plays an important role in the formation of tight junction complex.

Mouse (Murine) Platelet/endothelial Cell Adhesion Molecule (PECAM1) interaction partners

  1. These studies indicate a role for PECAM-1 in enhancing the inhibitory functions of TGF-beta (show TGFB1 Proteins) in T cells

  2. PECAM1 acts upstream of Gab1, promoting Gab1/Akt (show AKT1 Proteins)/eNOS (show NOS3 Proteins) phosphorylation and activation, thereby confers EC responsiveness to flow.

  3. Radiation-induced stress conditions induce a transient accumulation of granulocytes within the liver by down-regulation/absence of PECAM-1.

  4. CD31 gene transfer is sufficient to recapitulate the cytoprotective mechanisms in CD31(-) pancreatic beta cells, which become resistant to immune-mediated rejection when grafted in fully allogeneic recipients

  5. PECAM1+ melanoma cells form vascular channels

  6. Data indicate that in lymphocyte specific 1 (show LSP1 Proteins) protein (LSP1 (show LSP1 Proteins))-deficient mice, PECAM-1 expression was reduced in endothelial cells, but not in neutrophils.

  7. Nck (show NCK1 Proteins) promoted oxidative stress-induced (show SQSTM1 Proteins) activation of NF-kappaB (show NFKB1 Proteins) by coupling the tyrosine phosphorylation of PECAM-1 (platelet endothelial cell adhesion molecule-1) to the activation of p21-activated kinase

  8. PECAM-1 has a role in mediating the profibrotic and prometastasic environment caused by ethanol in endothelial cells

  9. the T cell co-inhibitory receptor CD31 prevents the formation of functional T/B immunological synapses and that therapeutic strategies aimed at sustaining CD31 signaling will attenuate the development of autoimmune responses in vivo.

  10. MMP-9 (show MMP9 Proteins) activity disrupts vascular integrity at least partially through a PECAM-1 dependent mechanism and interferes with regeneration of steatotic livers after ischemia/reperfusion injury.

CD31 (PECAM1) Protein Profile

Protein Summary

The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation.

Alternative names and synonyms associated with CD31 (PECAM1)

  • platelet/endothelial cell adhesion molecule (LOC569386)
  • platelet/endothelial cell adhesion molecule (PECAM1)
  • platelet/endothelial cell adhesion molecule 1 (PECAM1)
  • platelet/endothelial cell adhesion molecule 1 (Pecam1)
  • C85791 protein
  • Cd31 protein
  • CD31/EndoCAM protein
  • endoCAM protein
  • GPIIA' protein
  • PECA1 protein
  • Pecam protein
  • PECAM-1 protein

Protein level used designations for PECAM1

platelet endothelial cell adhesion molecule , CD31 antigen , PECAM-1 , platelet/endothelial cell adhesion molecule (CD31 antigen) , PECAM-1/CD31 , type I transmembrane endothelial adhesion molecule

GENE ID SPECIES
569386 Danio rerio
282303 Bos taurus
5175 Homo sapiens
18613 Mus musculus
29583 Rattus norvegicus
396941 Sus scrofa
100734230 Cavia porcellus
610775 Canis lupus familiaris
771243 Gallus gallus
100303608 Ovis aries
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