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Browse our anti-EGR1 (EGR1) Antibodies

Full name:
anti-Early Growth Response 1 Antibodies (EGR1)
On are 130 Early Growth Response 1 (EGR1) Antibodies from 24 different suppliers available. Additionally we are shipping EGR1 Kits (43) and EGR1 Proteins (19) and many more products for this protein. A total of 200 EGR1 products are currently listed.
A530045N19Rik, at225, egr, egr-1, EGR-1-A, EGR1, ETR103, g0s30, Krox-1, krox-24, krox24, Ngf1, NGF1-A, Ngfi, ngfi-a, NGFIA, tis8, wu:fj64b05, wu:fq25f01, Xegr-1, zenk, Zfp-6, zif-268, Zif268, znf225

Most Popular Reactivities for anti-EGR1 (EGR1) Antibodies

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anti-Human EGR1 Antibodies:

anti-Mouse (Murine) EGR1 Antibodies:

anti-Rat (Rattus) EGR1 Antibodies:

All available anti-EGR1 Antibodies

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Top referenced anti-EGR1 Antibodies

  1. Cow (Bovine) Polyclonal EGR1 Primary Antibody for IHC, WB - ABIN2779517 : Yu, de Belle, Liang, Adamson: Coactivating factors p300 and CBP are transcriptionally crossregulated by Egr1 in prostate cells, leading to divergent responses. in Molecular cell 2004 (PubMed)
    Show all 7 references for ABIN2779517

  2. Human Monoclonal EGR1 Primary Antibody for WB - ABIN394244 : Kim, Jeong, Jeong, Kim, Lee, Shin, Kye, Son: Cigarette smoke-induced Egr-1 represses T beta R-II expression in human skin dermal fibroblasts. in Toxicology 2010 (PubMed)
    Show all 5 references for ABIN394244

  3. Human Monoclonal EGR1 Primary Antibody for IF, WB - ABIN393945 : Xu, Toure, Qu, Lin, Song, Shen, Rosario, Garcia, Schmidt, Yan: Advanced glycation end product (AGE)-receptor for AGE (RAGE) signaling and up-regulation of Egr-1 in hypoxic macrophages. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for ABIN393945

  4. Chimpanzee Polyclonal EGR1 Primary Antibody for EIA, IHC (p) - ABIN401280 : Suggs, Katzowitz, Tsai-Morris, Sukhatme: cDNA sequence of the human cellular early growth response gene Egr-1. in Nucleic acids research 1990 (PubMed)
    Show all 3 references for ABIN401280

  5. Human Monoclonal EGR1 Primary Antibody for ELISA, WB - ABIN969092 : Chan, Lee, Ho, Wong, Lam, Tang, Chan, Abdullah, Wong, Lam: High-level expression of early growth response-1 and association of polymorphism with total IgE and atopy in allergic rhinitis adults. in Clinica chimica acta; international journal of clinical chemistry 2009 (PubMed)
    Show all 2 references for ABIN969092

  6. Human Polyclonal EGR1 Primary Antibody for FACS, IF - ABIN389442 : Zhang, Chen, Wang, Guang, Han, Zhang, Tan, Gu: EGR1 decreases the malignancy of human non-small cell lung carcinoma by regulating KRT18 expression. in Scientific reports 2014 (PubMed)
    Show all 2 references for ABIN389442

  7. Cow (Bovine) Polyclonal EGR1 Primary Antibody for IHC, WB - ABIN2779828 : Schnell, Zoller, Patel, Williams, Kersh: Early growth response gene 1 provides negative feedback to inhibit entry of progenitor cells into the thymus. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)

  8. Cow (Bovine) Polyclonal EGR1 Primary Antibody for WB - ABIN2774222 : Akutagawa, Nishi, Kyo, Terauchi, Yamazawa, Higuma, Inoue, Isaka: Early growth response-1 mediates downregulation of telomerase in cervical cancer. in Cancer science 2008 (PubMed)

More Antibodies against EGR1 Interaction Partners

Pig (Porcine) Early Growth Response 1 (EGR1) interaction partners

  1. Egr-1 silencing through intracoronary delivery of a targeting DNAzyme at the time of reperfusion following acute myocardial ischemia decreases myocardial inflammation and apoptosis leading to improved cardiac function.

  2. Intracoronary delivery of DNAzymes targeting human EGR-1 reduces infarct size following myocardial ischaemia reperfusion.

  3. Data suggest that Egr-1 protein levels may be tightly regulated in an attempt to diminish neurotoxicity or to enhance plasticity in newborn animals.

Human Early Growth Response 1 (EGR1) interaction partners

  1. Shikonin induces apoptosis in some lung cancer cells via activation of FOXO3a (show FOXO3 Antibodies)/EGR1/SIRT1 (show SIRT1 Antibodies) signaling, and AKT (show AKT1 Antibodies) and p300 (show EP300 Antibodies) negatively regulate this process via Bim (show BCL2L11 Antibodies) upregulation.

  2. Inhibition of mTORC1-mediated 4EBP1 (show EIF4EBP1 Antibodies) phosphorylation leads to decreased expression of c-MYC (show MYC Antibodies) and subsequent upregulation of the proapoptotic BCL2 (show BCL2 Antibodies) family member PUMA (show BBC3 Antibodies), whereas inhibition of mTORC2 (show CRTC2 Antibodies) results in nuclear factor-kappaB-mediated expression of the Early Growth Response 1 (EGR1) gene, which encodes a transcription factor that binds and transactivates the proapoptotic BCL2L11 (show BCL2L11 Antibodies) locus encoding BIM (show BCL2L11 Antibodies).

  3. Conversely, siRNA-mediated Klotho (show KL Antibodies) silencing up-regulated Egr-1, FN, and Col (show HDAC1 Antibodies) I expression and the p-Smad3/Smad3 (show SMAD3 Antibodies) ratio. Moreover, the effects of si-Klotho (show KL Antibodies) on Egr-1 expression were abolished by the TGF-beta1 (show TGFB1 Antibodies) inhibitor SB-431542. Klotho (show KL Antibodies) overexpression can prevent mesangial ECM (show MMRN1 Antibodies) production in high-glucose-treated human MCs (show SMCP Antibodies), an effect that has been partially attributed to Egr-1 down-regulation facilitated by TGF-beta1 (show TGFB1 Antibodies)/Smad3 (show SMAD3 Antibodies) s...

  4. ZHX1 (show ZHX1 Antibodies) was found to play essential roles in the proliferation, migration, and invasion of cholangiocarcinoma cells, and its effect on the proliferation was mediated partially through EGR1.

  5. Data show the correlation between the measured and predicted binding free energy values for Egr-1-DNA binding.

  6. SphK1 (show SPHK1 Antibodies) is regulated by PDGF (show PDGFA Antibodies)-BB in pulmonary artery smooth muscle cells via the transcription factor Egr-1, promoting cell proliferation.

  7. miR124 prevents tendon differentiation via suppressing egr1 expression.

  8. we propose a model whereby high YB-1 levels in some TNBC cells can lead to reduced levels of EGR1, which in turn promotes slow cell cycling and resistance to PTX. Therefore YB-1 and EGR1 levels are biologically linked and may provide a biomarker for TNBC response to PTX.

  9. TRAIL overexpression was co-regulated by Egr1 and Hypoxia response element. TRAIL might promote hypoxic A549 cell radiosensitivity and induce apoptosis depending on DR5 (show TNFRSF10B Antibodies) to caspase-3 (show CASP3 Antibodies) pathways.

  10. These results suggest that frameshift mutations of EGR1 and BRSK1 (show BRSK1 Antibodies) might play a role in tumorigenesis through tumor suppressor gene inactivation in colorectal cancer and gastric cancer.

Cow (Bovine) Early Growth Response 1 (EGR1) interaction partners

  1. Chronic hypoxia induces Egr-1 via activation of ERK1/2 (show MAPK1/3 Antibodies) and contributes to pulmonary vascular remodeling.

  2. The authors conclude that Egr-1 protein expression is very sensitive to upregulation by hypoxia in pulmonary artery adventitial fibroblasts and that it plays an important role in the autonomous growth phenotype induced by hypoxia in these cells.

  3. EGR-1's expression prior to ovulation and its stimulating effect on the expression of genes known to be involved in prostaglandin biosynthesis pathway, suggest its potential involvement in the regulation of preovulatory events in cattle.

Mouse (Murine) Early Growth Response 1 (EGR1) interaction partners

  1. Egr1 expression is sensitive to mechanical signals in tendon cells.

  2. age-related up-regulation of EGR1 promotes granulosa cell apoptosis in follicle atresia during ovarian aging.

  3. data indicate that Egr-1 promotes Abeta (show APP Antibodies) synthesis via transcriptional activation of BACE-1 (show BACE Antibodies) and suggest that Egr-1 plays role in activation of BACE-1 (show BACE Antibodies) and acceleration of Abeta (show APP Antibodies) synthesis in AD brain.

  4. EGR1, an early growth response factor, is a critical transcription factor that regulates the hepatic clock circuit.

  5. EGR1(-/-) mouse embryonic fibroblasts demonstrated lower susceptibility to Venezuelan equine encephalitis virus-induced cell death than isogenic wild-type fibroblasts, indicating that EGR1 modulates proapoptotic pathways following virus infection.

  6. The levels of B23 (show NPM1 Antibodies) expression are directly regulated by EGR1.

  7. our data demonstrate that the effect of FGF23 (show FGF23 Antibodies) on Pi homeostasis is mediated, at least in part, by activation of egr-1.

  8. associated with this behavior, that is, an increase in the expression of the immediate early (show JUN Antibodies) gene Early Growth Response protein 1 (EGR1, Zif268)

  9. Egr-1 is involved in NMDAR (show GRIN1 Antibodies)-mediated PSD-95 (show DLG4 Antibodies) down-regulation and AMPAR endocytosis, a process important in the expression of long term depression

  10. ERG1 (show KCNH2 Antibodies) overexpression led to the development of highly aggressive B-cell malignancies.

Zebrafish Early Growth Response 1 (EGR1) interaction partners

  1. egr1 colocalizes with tyrosine hydroxylase (show TH Antibodies) in the olfactory bulb throughout brain development.

  2. successive induction of the transcription factors Runx3, Egr1 and Sox9b constitutes a regulatory cascade that controls expression of Follistatin A in pharyngeal endoderm, the latter modulating BMP signaling in developing cranial cartilage in zebrafish

  3. The cDNA coding for zebrafish Egr1 was obtained and its expression pattern was examined during zebrafish embryogenesis using whole-mount in situ hybridization

  4. Egr1 gene has important role in zebrafish embryonic oculogenesis. Lens and retina with egr1 gene deletion were primitive and lacked differentiation. Such arrested retinal and lenticular development in Egr1 morphants resulted in microphthalmos.

Rabbit Early Growth Response 1 (EGR1) interaction partners

  1. Gene therapy using in vivo transfection of an Egr-1 decoy ODN significantly inhibits proliferation of VSMC and intimal hyperplasia of vein grafts in a rabbit model.

  2. Results show that EGR1 plays a key role in tendon formation, healing, and repair through BMP12 (show GDF7 Antibodies)/Smad1 (show SMAD1 Antibodies)/5/8 pathway.

  3. Collectively, these results demonstrate that Egr-1 is expressed rapidly upon HSV-1 infection and that this novel induction could be due to the NFsmall ka, CyrillicB/CREB (show CREB1 Antibodies)-mediated transactivation.

EGR1 Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene.

Alternative names and synonyms associated with EGR1

  • early growth response protein 1(Egr-1, NGFI-A) (EGR-1) antibody
  • early growth response protein 1 (egr-1) (CNK00890) antibody
  • early growth response 1 (EGR1) antibody
  • early growth response 1 (Egr1) antibody
  • early growth response 1 (egr1) antibody
  • early growth response 1 (egr1-a) antibody
  • early growth response protein 1 (EGR-1) antibody
  • A530045N19Rik antibody
  • at225 antibody
  • egr antibody
  • egr-1 antibody
  • EGR-1-A antibody
  • EGR1 antibody
  • ETR103 antibody
  • g0s30 antibody
  • Krox-1 antibody
  • krox-24 antibody
  • krox24 antibody
  • Ngf1 antibody
  • NGF1-A antibody
  • Ngfi antibody
  • ngfi-a antibody
  • NGFIA antibody
  • tis8 antibody
  • wu:fj64b05 antibody
  • wu:fq25f01 antibody
  • Xegr-1 antibody
  • zenk antibody
  • Zfp-6 antibody
  • zif-268 antibody
  • Zif268 antibody
  • znf225 antibody

Protein level used designations for EGR1

early growth response protein 1(Egr-1, NGFI-A) , early growth response protein 1 (egr-1) , early growth response 1 , EGR-1 , early growth response protein 1 , nerve growth factor-induced protein A , transcription factor ETR103 , transcription factor Zif268 , zinc finger protein 225 , zinc finger protein Krox-24 , Krox-24 nuclear protein , zinc finger protein ZENK , etID309970.14 , zinc-finger transcriptional protein , early growth response protein 1-A

397332 Sus scrofa
3254484 Cryptococcus neoformans var. neoformans JEC21
100618969 Monodelphis domestica
1958 Homo sapiens
481528 Canis lupus familiaris
407125 Bos taurus
13653 Mus musculus
24330 Rattus norvegicus
462097 Pan troglodytes
100716298 Cavia porcellus
100520726 Sus scrofa
373931 Gallus gallus
443547 Ovis aries
30498 Danio rerio
100008579 Taeniopygia guttata
399162 Xenopus laevis
100009491 Oryctolagus cuniculus
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