Browse our anti-EGR1 (EGR1) Antibodies

Full name:
anti-Early Growth Response 1 Antibodies (EGR1)
On are 132 Early Growth Response 1 (EGR1) Antibodies from 25 different suppliers available. Additionally we are shipping EGR1 Kits (45) and EGR1 Proteins (19) and many more products for this protein. A total of 204 EGR1 products are currently listed.
A530045N19Rik, at225, egr, egr-1, EGR-1-A, EGR1, ETR103, g0s30, Krox-1, krox-24, krox24, Ngf1, NGF1-A, Ngfi, ngfi-a, NGFIA, tis8, wu:fj64b05, wu:fq25f01, Xegr-1, zenk, Zfp-6, zif-268, Zif268, znf225

Most Popular Reactivities for anti-EGR1 (EGR1) Antibodies

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anti-Human EGR1 Antibodies:

anti-Mouse (Murine) EGR1 Antibodies:

anti-Rat (Rattus) EGR1 Antibodies:

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Top referenced anti-EGR1 Antibodies

  1. Cow (Bovine) Polyclonal EGR1 Primary Antibody for IHC, WB - ABIN2779517 : Yu, de Belle, Liang, Adamson: Coactivating factors p300 and CBP are transcriptionally crossregulated by Egr1 in prostate cells, leading to divergent responses. in Molecular cell 2004 (PubMed)
    Show all 8 references for 2779517

  2. Human Monoclonal EGR1 Primary Antibody for IF, WB - ABIN393945 : Kim, Jeong, Jeong, Kim, Lee, Shin, Kye, Son: Cigarette smoke-induced Egr-1 represses T beta R-II expression in human skin dermal fibroblasts. in Toxicology 2010 (PubMed)
    Show all 5 references for 393945

  3. Human Monoclonal EGR1 Primary Antibody for WB - ABIN394244 : Xu, Toure, Qu, Lin, Song, Shen, Rosario, Garcia, Schmidt, Yan: Advanced glycation end product (AGE)-receptor for AGE (RAGE) signaling and up-regulation of Egr-1 in hypoxic macrophages. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for 394244

  4. Human Monoclonal EGR1 Primary Antibody for ELISA, WB - ABIN969092 : Chan, Lee, Ho, Wong, Lam, Tang, Chan, Abdullah, Wong, Lam: High-level expression of early growth response-1 and association of polymorphism with total IgE and atopy in allergic rhinitis adults. in Clinica chimica acta; international journal of clinical chemistry 2009 (PubMed)
    Show all 2 references for 969092

  5. Human Polyclonal EGR1 Primary Antibody for FACS, IF - ABIN389442 : Zhang, Chen, Wang, Guang, Han, Zhang, Tan, Gu: EGR1 decreases the malignancy of human non-small cell lung carcinoma by regulating KRT18 expression. in Scientific reports 2014 (PubMed)
    Show all 2 references for 389442

  6. Cow (Bovine) Polyclonal EGR1 Primary Antibody for WB - ABIN2774222 : Akutagawa, Nishi, Kyo, Terauchi, Yamazawa, Higuma, Inoue, Isaka: Early growth response-1 mediates downregulation of telomerase in cervical cancer. in Cancer science 2008 (PubMed)

  7. Cow (Bovine) Polyclonal EGR1 Primary Antibody for IHC, WB - ABIN2779828 : Schnell, Zoller, Patel, Williams, Kersh: Early growth response gene 1 provides negative feedback to inhibit entry of progenitor cells into the thymus. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)

More Antibodies against EGR1 Interaction Partners

Pig (Porcine) Early Growth Response 1 (EGR1) interaction partners

  1. Egr-1 silencing through intracoronary delivery of a targeting DNAzyme at the time of reperfusion following acute myocardial ischemia decreases myocardial inflammation and apoptosis leading to improved cardiac function.

  2. Intracoronary delivery of DNAzymes targeting human EGR-1 reduces infarct size following myocardial ischaemia reperfusion.

  3. Data suggest that Egr-1 protein levels may be tightly regulated in an attempt to diminish neurotoxicity or to enhance plasticity in newborn animals.

Human Early Growth Response 1 (EGR1) interaction partners

  1. Finally, the authors show that EGFR (show EGFR Antibodies)-ERK1/2 (show MAPK1/3 Antibodies) and beta1-integrin signaling are the main pathways used for bacteria-mediated EGR1 upregulation.

  2. Early growth response (Egr)-1 is essential for fibrotic responses to Transforming growth factor (TGF)-beta (show TGFB1 Antibodies). Egr-1 mediates TGF-beta1 (show TGFB1 Antibodies)-induced COL1A1 (show COL1A1 Antibodies) and COL1A2 (show COL1A2 Antibodies) mRNA expression and acid-soluble collagen production in buccal mucosal fibroblasts (BMFs).The epigallocatechin-3-gallate (EGCG) can block TGF-beta1 (show TGFB1 Antibodies)-induced collagen production by attenuating Egr-1 expression in BMFs.

  3. Along with the reduction of ovarian cancer-2/disabled homolog 2 (DOC-2 (show DAB2 Antibodies)/DAB2) interactive protein (DAB2IP (show DAB2IP Antibodies)) expression, EGR-1 gene was upregulated in FI-treated cells. On the other hand, downregulation of EGR-1 gene expression sensitized radioresistant cells to IR accompanied by DAB2IP (show DAB2IP Antibodies) overexpression and STAT3 (show STAT3 Antibodies) inactivation. In addition, NF-kappaB (show NFKB1 Antibodies) inhibitor, BAY11-7082 enhanced resistant cells' radiosensitivity and chemos...

  4. ROS (show ROS1 Antibodies) activation of the MAPK (ERK (show MAPK1 Antibodies)-1 (show MAPK3 Antibodies)/2)/Egr-1 pathway is a main player in the regulatory mechanism for cigarette smoke extract-induced PlGF (show PGF Antibodies) production. Antioxidants could partly abolish these effects.

  5. adipose tissue-derived mesenchymal stem cells (AT-MSCs) from diabetic patients may contribute to microvascular damage and delay wound healing through the overexpression of EGR-1.

  6. KLF12 (show KLF12 Antibodies) promotes tumor growth by directly activating early growth response protein 1 (EGR1). The levels of KLF12 (show KLF12 Antibodies) and EGR1 correlate synergistically with a poor prognosis. These results indicate that KLF12 (show KLF12 Antibodies) likely plays an important role in CRC (show CALR Antibodies) and could serve as a potential prognostic marker and therapeutic target.

  7. Shikonin induces apoptosis in some lung cancer cells via activation of FOXO3a (show FOXO3 Antibodies)/EGR1/SIRT1 (show SIRT1 Antibodies) signaling, and AKT (show AKT1 Antibodies) and p300 (show EP300 Antibodies) negatively regulate this process via Bim (show BCL2L11 Antibodies) upregulation.

  8. Inhibition of mTORC1-mediated 4EBP1 (show EIF4EBP1 Antibodies) phosphorylation leads to decreased expression of c-MYC (show MYC Antibodies) and subsequent upregulation of the proapoptotic BCL2 (show BCL2 Antibodies) family member PUMA (show BBC3 Antibodies), whereas inhibition of mTORC2 (show CRTC2 Antibodies) results in nuclear factor-kappaB-mediated expression of the Early Growth Response 1 (EGR1) gene, which encodes a transcription factor that binds and transactivates the proapoptotic BCL2L11 (show BCL2L11 Antibodies) locus encoding BIM (show BCL2L11 Antibodies).

  9. Conversely, siRNA-mediated Klotho (show KL Antibodies) silencing up-regulated Egr-1, FN, and Col (show HDAC1 Antibodies) I expression and the p-Smad3/Smad3 (show SMAD3 Antibodies) ratio. Moreover, the effects of si-Klotho (show KL Antibodies) on Egr-1 expression were abolished by the TGF-beta1 (show TGFB1 Antibodies) inhibitor SB-431542. Klotho (show KL Antibodies) overexpression can prevent mesangial ECM (show MMRN1 Antibodies) production in high-glucose-treated human MCs (show SMCP Antibodies), an effect that has been partially attributed to Egr-1 down-regulation facilitated by TGF-beta1 (show TGFB1 Antibodies)/Smad3 (show SMAD3 Antibodies) s...

  10. ZHX1 (show ZHX1 Antibodies) was found to play essential roles in the proliferation, migration, and invasion of cholangiocarcinoma cells, and its effect on the proliferation was mediated partially through EGR1.

Cow (Bovine) Early Growth Response 1 (EGR1) interaction partners

  1. Chronic hypoxia induces Egr-1 via activation of ERK1/2 (show MAPK1/3 Antibodies) and contributes to pulmonary vascular remodeling.

  2. The authors conclude that Egr-1 protein expression is very sensitive to upregulation by hypoxia in pulmonary artery adventitial fibroblasts and that it plays an important role in the autonomous growth phenotype induced by hypoxia in these cells.

  3. EGR-1's expression prior to ovulation and its stimulating effect on the expression of genes known to be involved in prostaglandin biosynthesis pathway, suggest its potential involvement in the regulation of preovulatory events in cattle.

Mouse (Murine) Early Growth Response 1 (EGR1) interaction partners

  1. Herein, we report that silencing of Egr-1 in the hippocampus by shRNA reduces tau phosphorylation, lowers amyloid-beta (Abeta (show APP Antibodies)) pathology, and improves cognition in the 3xTg-Alzheimer disease mouse model.

  2. Egr-1 is a novel regulator of drebrin (show DBN1 Antibodies) expression, which is linked to changes in dendritic spine density

  3. In the present study, we have investigated the contribution of element C to Krox20 (show EGR2 Antibodies) expression, as it was the only characterized initiator element with an activity in r3. Using a conditional knock-out mutation of element C, we show that, unexpectedly, this element is not necessary for Krox20 (show EGR2 Antibodies) initial expression in r3.

  4. HAS2 (show HAS2 Antibodies)-produced hyaluronan is required for CD44V6 and TGFbetaRI co-localization and subsequent CD44V6/ERK1 (show MAPK3 Antibodies)/EGR1 signaling. These results demonstrate a novel positive-feedback loop that links the myofibroblast phenotype to TGFbeta1 (show TGFB1 Antibodies)-stimulated CD44V6/ERK (show EPHB2 Antibodies)/EGR1 signaling.

  5. Egr1 expression is sensitive to mechanical signals in tendon cells.

  6. age-related up-regulation of EGR1 promotes granulosa cell apoptosis in follicle atresia during ovarian aging.

  7. data indicate that Egr-1 promotes Abeta (show APP Antibodies) synthesis via transcriptional activation of BACE-1 (show BACE Antibodies) and suggest that Egr-1 plays role in activation of BACE-1 (show BACE Antibodies) and acceleration of Abeta (show APP Antibodies) synthesis in AD brain.

  8. EGR1, an early growth response factor, is a critical transcription factor that regulates the hepatic clock circuit.

  9. EGR1(-/-) mouse embryonic fibroblasts demonstrated lower susceptibility to Venezuelan equine encephalitis virus-induced cell death than isogenic wild-type fibroblasts, indicating that EGR1 modulates proapoptotic pathways following virus infection.

  10. The levels of B23 (show NPM1 Antibodies) expression are directly regulated by EGR1.

Zebrafish Early Growth Response 1 (EGR1) interaction partners

  1. egr1 colocalizes with tyrosine hydroxylase (show TH Antibodies) in the olfactory bulb throughout brain development.

  2. successive induction of the transcription factors Runx3, Egr1 and Sox9b constitutes a regulatory cascade that controls expression of Follistatin A in pharyngeal endoderm, the latter modulating BMP signaling in developing cranial cartilage in zebrafish

  3. The cDNA coding for zebrafish Egr1 was obtained and its expression pattern was examined during zebrafish embryogenesis using whole-mount in situ hybridization

  4. Egr1 gene has important role in zebrafish embryonic oculogenesis. Lens and retina with egr1 gene deletion were primitive and lacked differentiation. Such arrested retinal and lenticular development in Egr1 morphants resulted in microphthalmos.

Rabbit Early Growth Response 1 (EGR1) interaction partners

  1. Gene therapy using in vivo transfection of an Egr-1 decoy ODN significantly inhibits proliferation of VSMC and intimal hyperplasia of vein grafts in a rabbit model.

  2. Results show that EGR1 plays a key role in tendon formation, healing, and repair through BMP12 (show GDF7 Antibodies)/Smad1 (show SMAD1 Antibodies)/5/8 pathway.

  3. Collectively, these results demonstrate that Egr-1 is expressed rapidly upon HSV-1 infection and that this novel induction could be due to the NFsmall ka, CyrillicB/CREB (show CREB1 Antibodies)-mediated transactivation.

EGR1 Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene.

Alternative names and synonyms associated with EGR1

  • early growth response protein 1(Egr-1, NGFI-A) (EGR-1) antibody
  • early growth response protein 1 (egr-1) (CNK00890) antibody
  • early growth response 1 (EGR1) antibody
  • early growth response 1 (Egr1) antibody
  • early growth response 1 (egr1) antibody
  • early growth response 1 (egr1-a) antibody
  • early growth response protein 1 (EGR-1) antibody
  • A530045N19Rik antibody
  • at225 antibody
  • egr antibody
  • egr-1 antibody
  • EGR-1-A antibody
  • EGR1 antibody
  • ETR103 antibody
  • g0s30 antibody
  • Krox-1 antibody
  • krox-24 antibody
  • krox24 antibody
  • Ngf1 antibody
  • NGF1-A antibody
  • Ngfi antibody
  • ngfi-a antibody
  • NGFIA antibody
  • tis8 antibody
  • wu:fj64b05 antibody
  • wu:fq25f01 antibody
  • Xegr-1 antibody
  • zenk antibody
  • Zfp-6 antibody
  • zif-268 antibody
  • Zif268 antibody
  • znf225 antibody

Protein level used designations for EGR1

early growth response protein 1(Egr-1, NGFI-A) , early growth response protein 1 (egr-1) , early growth response 1 , EGR-1 , early growth response protein 1 , nerve growth factor-induced protein A , transcription factor ETR103 , transcription factor Zif268 , zinc finger protein 225 , zinc finger protein Krox-24 , Krox-24 nuclear protein , zinc finger protein ZENK , etID309970.14 , zinc-finger transcriptional protein , early growth response protein 1-A

397332 Sus scrofa
3254484 Cryptococcus neoformans var. neoformans JEC21
100618969 Monodelphis domestica
1958 Homo sapiens
481528 Canis lupus familiaris
407125 Bos taurus
13653 Mus musculus
24330 Rattus norvegicus
462097 Pan troglodytes
100716298 Cavia porcellus
100520726 Sus scrofa
373931 Gallus gallus
443547 Ovis aries
30498 Danio rerio
100008579 Taeniopygia guttata
399162 Xenopus laevis
100009491 Oryctolagus cuniculus
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