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Human CXCL12 ELISA Kit for Sandwich ELISA - ABIN414920
Patschan, Patschan, Temme, Korsten, Wessels, Koziolek, Henze, Müller: Endothelial progenitor cells (EPC) in sepsis with acute renal dysfunction (ARD). in Critical care 2011
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Mouse (Murine) CXCL12 ELISA Kit for Sandwich ELISA - ABIN625176
Shirozu, Nakano, Inazawa, Tashiro, Tada, Shinohara, Honjo: Structure and chromosomal localization of the human stromal cell-derived factor 1 (SDF1) gene. in Genomics 1996
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Human CXCL12 ELISA Kit for Sandwich ELISA - ABIN625084
Gravina, Mancini, Ranieri, Di Pasquale, Marampon, Di Clemente, Ricevuto, Festuccia: Phenotypic characterization of human prostatic stromal cells in primary cultures derived from human tissue samples. in International journal of oncology 2013
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Rat (Rattus) CXCL12 ELISA Kit for Sandwich ELISA - ABIN416336
Tong, Xu, Han, Chen, Yang, Qiao, Hong, Wu, Zhou et al.: Tanshinone IIA increases recruitment of bone marrow mesenchymal stem cells to infarct region via up-regulating stromal cell-derived factor-1/CXC chemokine receptor 4 axis in a myocardial ischemia ... in Phytomedicine : international journal of phytotherapy and phytopharmacology 2011
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Mouse (Murine) CXCL12 ELISA Kit for Sandwich ELISA - ABIN415535
Shi, Wang, Zhang, Cai, Zhou, Hou, van Rooijen: Monocyte/macrophages promote vasculogenesis in choroidal neovascularization in mice by stimulating SDF-1 expression in RPE cells. in Graefe's archive for clinical and experimental ophthalmology 2011
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these results demonstrate that a cross-talk exists between the TGF-beta1 (show TGFB1 ELISA Kits) and SDF-1 pathways in choroid-retinal endothelial cells
following optic nerve crush, the levels of endogenous SDF-1alpha and CXCR4 (show CXCR4 ELISA Kits) increase in the retina and optic nerve, where activated glial cells may act as a source of increased SDF-1alpha protein.
The CXCR7 (show CXCR7 ELISA Kits)/CXCR4 (show CXCR4 ELISA Kits)/CXCL12 axis plays an important role in the formation of CNV, and may become a novel target for the treatment of choroidal neovascularization-associated diseases.
primordial germ cell movements are shown to be the consequence of a combination of active SDF1a and SDF1b-guided migration; both SDF1 co-orthologues show only partly overlapping expression pattern and cooperate in the correct positioning of the PGCs
CCR1 activation potently induces multiple myeloma PC migration toward CCL3 (show CCL3 ELISA Kits) while abrogating the multiple myeloma PC migratory response to CXCL12.
High CXCL12 expression is associated with gemcitabine resistance in pancreatic cancer.
CXCL12 expression may be a useful marker for predicting the outcome in patients with esophageal squamous cell carcinoma and is a potentially new therapeutic target
our findings indicate the functional role of HBx in regulating the stem-like properties of OV6(+) CSCs in HCC (show FAM126A ELISA Kits) through the MDM2 (show MDM2 ELISA Kits)/CXCL12/CXCR4 (show CXCR4 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signaling axis, and identify HBx, MDM2 (show MDM2 ELISA Kits), CXCR4 (show CXCR4 ELISA Kits) and OV6 as a novel prognostic pathway and potential therapeutic targets for patients with HBV-related HCC (show FAM126A ELISA Kits) patients
study revealed that the CXCL12-CXCR4 (show CXCR4 ELISA Kits) interaction is crucial for stromal cell contact-mediated early B lymphoid and pDC (show PNKD ELISA Kits) differentiation from immature hematopoietic and early T lymphoid precursors with a multilineage differentiation potential but not for stromal cell contact-independent generation of early T lymphoid precursors.
SDF-1, CXCR4 (show CXCR4 ELISA Kits) ligand, was highly expressed in mesenchymal stem cells when co-cultured with degenerated nucleus pulposus cells. Inhibition of SDF-1 using CXCR4 (show CXCR4 ELISA Kits) antagonist AMD3100 abolished the MSCs-induced decrease in the mechanical moduli and increased biological activity of degenerated NPCs, suggesting a crucial role for SDF-1/CXCR4 (show CXCR4 ELISA Kits) signaling.
Cathepsin K (show CTSK ELISA Kits) cleavage of SDF-1alpha inhibits its chemotactic activity towards glioblastoma stem-like cells.
High CXCL12 expression is associated with glioblastoma resistance to radiotherapy.
SDF-1 promoted the proliferation of gastric cancer SGC (show SGCB ELISA Kits)-7901 cells, the phosphorylation of ERK1/2 (show MAPK1/3 ELISA Kits), p38 (show CRK ELISA Kits) and CXCR7 (show CXCR7 ELISA Kits) knockdown distinctly reversed these changes; the proliferation stimulated with SDF-1 was attenuated by U0126 (MEK1 (show MAP2K1 ELISA Kits)/2 inhibitor).
Results show that SDF-1 and IL-6 expression level is regulated by CHEK2 in breast stromal fibroblasts.
The results of this study suggested that enhanced interaction between STAT3 (show STAT3 ELISA Kits) and p300 (show NOTCH1 ELISA Kits) mediated the epigenetic upregulation of CXCL12 in dorsal horn neurons, which contributed to the antitubulin chemotherapeutics-induced persistent pain
Dipeptidyl peptidase-4 (show DPP4 ELISA Kits) inhibition, independent of glucagon-like peptide-1 receptor (show GLP1R ELISA Kits) signaling, contributes to protection of the diabetic kidney through SDF-1-dependent antioxidative and antifibrotic effects and amelioration of adverse renal hemodynamics.
High Cxcl12 expression is associated with Prostate Cancer.
Authors demonstrate that targeting the SDF-1/CXCR4 pathway in the context of KLF10 deletion substantially suppresses PDAC progression
Adipocytes promoted osteoclast differentiation, function and expression of adhesion-related molecules through the CXCL12/CXCR4 (show CXCR4 ELISA Kits) signalling pathway.
these findings demonstrate that expression of Hmga2 cooperates with Jak2 (show JAK2 ELISA Kits)(V617F) in the pathogenesis of Mmyelofibrosis.
Data demonstrated that sustained expression of CXCL12 by MSCs in the primary tumour site inhibits metastasis through reduction of CXCR7 (show CXCR7 ELISA Kits), while, in the presence of TGFbeta (show TGFB1 ELISA Kits), this CXCL12 effect of MSCs on tumour cells is relieved.
CXCL12 upregulation prior to stroke onset, and its actions following stroke, contribute to the endogenous, anti-inflammatory phenotype induced by repetitive hypoxic preconditioning
Results suggest that SDF-1/CXCR4 (show CXCR4 ELISA Kits) signaling plays an important role in the dynamics associated with adult sub-ventricular zone lineage cell proliferation and differentiation.
TNF (show TNF ELISA Kits) plays an inhibitory role in modulating myocardial SDF-1 production and blockade of TNF (show TNF ELISA Kits) signaling by ablation of TNFR1 (show TNFRSF1A ELISA Kits) and TNFR2 (show TNFRSF1B ELISA Kits) genes increased SDF-1 expression in the heart. These data expand on TNF (show TNF ELISA Kits) signaling-initiated mechanisms in myocardium, which may lend a more complete understanding of SDF-1 and TNFR (show TNFRSF1A ELISA Kits)-derived actions in hopes of advancing ischemic heart injury treatments.
expression patterns of xSDF-1a, xCXCR4, and xCXCR7 during gastrulation; results suggest SDF-1 signaling supports migration of the mesendoderm cell cohort toward the animal pole and that activin/nodal signaling acts as a regulator of the expression of xSDF-1a and xCXCR4, but not xCXCR7
SDF-1/CXCR4 chemokine (show CCL1 ELISA Kits) signaling is involved in the migration and survival or in the differentiation of PGCs in Xenopus
A significant increase of stromal cell-derived factor-1alpha and CXCR4 was observed in protein extracts of idiopathic inflammatory myopathies in comparison with normal controls.
SDF-1 signaling is necessary for migrations of massive numbers of cells during gastrulation.
Polymorphisms in CXCL12 are significantly associated with immunological traits in Landrace piglets and have potential application value for marker-assisted selection of pig breeding with disease resistance.
The new method has shown to be capable of promoting CSCs proliferation and differentiation into cardiomyocytes through activating the SDF-1/CXCR4 (show CXCR4 ELISA Kits) axis, while inhibiting myocardial apoptosis , thereby enhancing myocardial regeneration.
There is a potential link between follicular SDF1/CXCR4 (show CXCR4 ELISA Kits) activation and the regulation of ovulation-related genes in cows and horses.
Polymorphism of intron 2 of the SDF1 gene in Galloway, Hereford, and Russian Black Pied cattle
This gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.
chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)
, chemokine CXCL12/SDF-1ALPHA
, stromal cell-derived factor 1
, stromal cell-derived factor 1 isoform alpha
, stromal cell-derived factor 1 isoform gamma
, stromal cell-derived factor 1a
, intercrine reduced in hepatomas
, pre-B cell growth-stimulating factor
, 12-O-tetradecanoylphorbol 13-acetate repressed protein 1
, pre-B-cell growth-stimulating factor
, thymic lymphoma cell-stimulating factor
, C-X-C motif chemokine 12
, stromal-derived factor 1
, chemokine ligand 12b
, stromal cell derived factor 1
, stromal cell-derived factor-1 beta
, CXC chemokine
, CXCL12 chemokine
, SDF-1 gamma
, Stromal cell-derived factor 1
, stromal cell-derived factor-1 gamma