Browse our anti-CXCR4 (CXCR4) Antibodies

Full name:
anti-Chemokine (C-X-C Motif) Receptor 4 Antibodies (CXCR4)
On www.antibodies-online.com are 512 Chemokine (C-X-C Motif) Receptor 4 (CXCR4) Antibodies from 39 different suppliers available. Additionally we are shipping CXCR4 Kits (46) and CXCR4 Proteins (17) and many more products for this protein. A total of 591 CXCR4 products are currently listed.
Synonyms:
cb403, CD184, Cmkar4, CXC-R4, CXC-R4-B, CXCR-4, CXCR-4-B, CXCR4, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, PB-CKR, PBSF/SDF-1, Sdf1r, WHIM, xcxcr4, zgc:109863
list all antibodies Gene Name GeneID UniProt
CXCR4 12767 P70658
CXCR4 60628  
CXCR4 7852 P61073

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Top referenced anti-CXCR4 Antibodies

  1. Human Polyclonal CXCR4 Primary Antibody for FACS, IF (p) - ABIN730888 : Zhuo, Jia, Song, Lu, Ding, Wang, Song, Fu, Luo: The CXCL12-CXCR4 chemokine pathway: a novel axis regulates lymphangiogenesis. in Clinical cancer research : an official journal of the American Association for Cancer Research 2012 (PubMed)
    Show all 12 references for 730888

  2. Mouse (Murine) Monoclonal CXCR4 Primary Antibody for FACS - ABIN4895484 : Tarrant, Billard, Timoshchenko, McGinnis, Serafin, Foreman, Esserman, Chao, Lento, Lee, Patel, Siderovski: G protein-coupled receptor kinase-3-deficient mice exhibit WHIM syndrome features and attenuated inflammatory responses. in Journal of leukocyte biology 2013 (PubMed)
    Show all 6 references for 4895484

  3. Human Monoclonal CXCR4 Primary Antibody for FACS - ABIN2853593 : Nimura, Zhang, Okuma, Tanaka, Sunakawa, Yamamoto, Tanaka: Cross-linking cell surface chemokine receptors leads to isolation, activation, and differentiation of monocytes into potent dendritic cells. in Experimental biology and medicine (Maywood, N.J.) 2006 (PubMed)
    Show all 4 references for 2853593

  4. Chimpanzee Monoclonal CXCR4 Primary Antibody for FACS, IHC (fro) - ABIN264477 : Endres, Clapham, Marsh, Ahuja, Turner, McKnight, Thomas, Stoebenau-Haggarty, Choe, Vance, Wells, Power, Sutterwala, Doms, Landau, Hoxie: CD4-independent infection by HIV-2 is mediated by fusin/CXCR4. in Cell 1997 (PubMed)
    Show all 3 references for 264477

  5. Human Polyclonal CXCR4 Primary Antibody for EIA, IHC (fro) - ABIN492892 : Tran, Miller: Chemokine receptors: signposts to brain development and disease. in Nature reviews. Neuroscience 2003 (PubMed)
    Show all 3 references for 492892

  6. Mouse (Murine) Monoclonal CXCR4 Primary Antibody for FACS - ABIN4895478 : Kremer, Dudakovic, McGee-Lawrence, Philips, Hess, Smith, van Wijnen, Karp, Kaufmann, Westendorf, Hedin: Osteoblasts protect AML cells from SDF-1-induced apoptosis. in Journal of cellular biochemistry 2014 (PubMed)
    Show all 2 references for 4895478

  7. Human Polyclonal CXCR4 Primary Antibody for IP, IHC - ABIN223559 : Miwa, Mizokami, Keller, Taichman, Zhang, Namiki: The bisphosphonate YM529 inhibits osteolytic and osteoblastic changes and CXCR-4-induced invasion in prostate cancer. in Cancer research 2005 (PubMed)

  8. Human Polyclonal CXCR4 Primary Antibody for IF, ELISA - ABIN1535575 : Federsppiel, Melhado, Duncan, Delaney, Schappert, Clark-Lewis, Jirik: Molecular cloning of the cDNA and chromosomal localization of the gene for a putative seven-transmembrane segment (7-TMS) receptor isolated from human spleen. in Genomics 1993 (PubMed)

  9. Mouse (Murine) Monoclonal CXCR4 Primary Antibody for FACS - ABIN4895482 : Hajishengallis, Wang, Liang, Triantafilou, Triantafilou: Pathogen induction of CXCR4/TLR2 cross-talk impairs host defense function. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

  10. Horse (Equine) Polyclonal CXCR4 Primary Antibody for FACS, IHC - ABIN2779387 : Yoshitake, Fukui, Yamagishi, Sekikawa, Fujii, Tomita, Ichikawa, Imura, Hiraishi, Fujimori: Expression of SDF-1 alpha and nuclear CXCR4 predicts lymph node metastasis in colorectal cancer. in British journal of cancer 2008 (PubMed)

More Antibodies against CXCR4 Interaction Partners

Medaka Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

  1. bilateral lineup in the trunk before PGC (show PGC PLURAL_@9242@) migration colonizing gonadal areas is defective in PGCS expressing a missense mutation in chemokine receptor (show CCR1 PLURAL_@9242@) gene cxcr4b

Mouse (Murine) Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

  1. Adipocytes promoted osteoclast differentiation, function and expression of adhesion-related molecules through the CXCL12 (show CXCL12 Antibodies)/CXCR4 signalling pathway.

  2. Efficient Cxcr4 desensitization is critical for lymphoid differentiation of hematopoietic stem and progenitor cell (HSPC (show PSMA7 Antibodies)), and its impairment is a key mechanism underpinning the lymphopenia observed in mice and likely in WHIM Syndrome (WS) patients.

  3. COUP-TFI (show NR2F1 Antibodies) is required predominantly in Dentate gyrus progenitors for modulating expression of the Cxcr4 receptor during granule cell neurogenesis and migration.

  4. CXCR4, CCR2 (show CCR2 Antibodies), and CX3CR1 (show CX3CR1 Antibodies) direct dendritic cell precursors from the bone marrow to the lung differentially.

  5. data suggest that prolonged but reversible pharmacologic blockade of the CXCR4/CXCL12 axis represents an approach that releases HSPC with efficiency superior to any other known mobilization strategy and may also serve as an effective method to expand the BM HSPC pool.

  6. role of MIM (show MTSS1 Antibodies) in the homeostasis of BM cells, including HSPCs, through modulation of the CXCR4/SDF-1 (show CXCL12 Antibodies) axis and interactions of BM leukocytes with their microenvironments.

  7. Results suggest that SDF-1 (show CXCL12 Antibodies)/CXCR4 signaling plays an important role in the dynamics associated with adult sub-ventricular zone lineage cell proliferation and differentiation.

  8. Matn4 and cytokine receptor CXCR4 involved in the regulation of hematopoietic stem cell proliferation and expansion under acute stress.

  9. This study demonstrates the multifaceted role of CXCR4 in defining BM monocyte heterogeneity and in regulating their function in peripheral tissues.

  10. this study shows that transmembrane TNF-alpha (show TNF Antibodies) upregulates CXCR4 expression that promotes chemotaxis of myeloid-derived suppressor cells to tumor, and give a new insight into a novel mechanism by which TNF-alpha (show TNF Antibodies) facilitates tumor immune evasion

Human Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

  1. CXCR4 and CXCR2 (show CXCR2 Antibodies) were highly expressed in a high invasive gastric cancer cell model and in gastric cancer tissues; crosstalk between CXCR4 and CXCR2 (show CXCR2 Antibodies) contributed to EMT (show ITK Antibodies), migration and invasion of gastric cancer.

  2. The findings on the positive cooperativity of viral GPCR with cellular CXCR4 in T cell activation extend our current understanding of the molecular mechanisms of viral GPCR function and highlight the importance of heteromerization for GPCR activity.

  3. upon ligation of the T-cell antigen receptor (TCR), the TCR associates with and transactivates CXCR4 via phosphorylation of S339-CXCR4 in order to activate a PREX1 (show PREX1 Antibodies)-Rac1-signaling pathway that stabilizes interleukin-2(IL-2 (show IL2 Antibodies)), IL-4 (show IL4 Antibodies), and IL-10 (show IL10 Antibodies) messenger RNA (mRNA) transcripts.

  4. Sporadic hemangioblastomas overexpress CXCR4 compared to VHL (show VHL Antibodies)-related hemangioblastoma.

  5. These results suggest that that CXCL14 (show CXCL14 Antibodies) is a positive allosteric modulator of CXCR4 via CXCL12 (show CXCL12 Antibodies) that enhances the potency of CXCR4 ligands.

  6. Mass spectrometry of CXCR4 immunoprecipitates revealed a specific interaction with the pentameric eukaryotic translation initiation factor (show EIF2A Antibodies) 2B.

  7. CXC chemokine receptor 4 may constitute a pharmacologic target for T cell acute lymphoblastic leukemia neuropathology.

  8. this study shows that CXCL12 (show CXCL12 Antibodies) conveys epithelial-mesenchymal transition -promoting signals in neuroendocrine tumors cells through CXCR4

  9. these results unveil a novel role of iCSCs in breast cancer metastasis as parental regulators of CXCR4(+) mCSCs, and highlight the therapeutic requisite of targeting iCSCs, but not CXCR4(+) mCSCs, to restrain breast cancer metastasis from the root by inhibiting the generation of mCSCs from iCSCs. Considering the pivotal role of iCSCs in tumor metastasis, the possibility of metastasis to be a 'stem cell phenomena' is sugge

  10. High CXCR4 expression is associated with Medulloblastoma.

Pig (Porcine) Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

  1. CXCR4 controls leukocyte mobilization after trauma.

  2. The new method has shown to be capable of promoting CSCs proliferation and differentiation into cardiomyocytes through activating the SDF-1 (show CXCL12 Antibodies)/CXCR4 axis, while inhibiting myocardial apoptosis , thereby enhancing myocardial regeneration.

  3. reports transmural and perivascular expression patterns of chemokines CCL2 (show CCL2 Antibodies) and CXCL2 (show CXCL2 Antibodies) and of chemokine (show CCL1 Antibodies) receptors CCR2 (show CCR2 Antibodies), CCR5, and CXCR4 following coronary angioplasty

Xenopus laevis Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

Cow (Bovine) Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

  1. The current analysis failed in identifying a causal mutation on the CXCR4 gene underlying a previously reported quantitative trait loci for cattle trypanotolerance on bovine chromosome 2.

  2. There is a potential link between follicular SDF1 (show CXCL12 Antibodies)/CXCR4 activation and the regulation of ovulation-related genes in cows and horses.

  3. The combination of low expression of CXCR4 and high expression of IL-10 (show IL10 Antibodies) might be closely concerned with some bias for the production of PI calves.

Rhesus Monkey Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

  1. The increased CXCR4 and CXCR7 (show CXCR7 Antibodies) expression resulted in increased SDF-1 (show CXCL12 Antibodies)-induced RF/6A cell migration and tube formation.

  2. The CXCR7 (show CXCR7 Antibodies)/CXCR4/CXCL12 (show CXCL12 Antibodies) axis plays an important role in the formation of CNV, and may become a novel target for the treatment of choroidal neovascularization-associated diseases.

  3. These findings suggest that FBLN5 (show FBLN5 Antibodies) may interfere with choroidal neovascularization by downregulating VEGF (show VEGFA Antibodies), CXCR4, and TGFB1 (show TGFB1 Antibodies) expression and inhibiting choroidl endothelial cell proliferation.

  4. Virus recovered from CA28 plasma (SHIV(CA28NP)) used both CCR5 and CXCR4 for entry, but the virus recovered from lymph node (SHIV(CA28NL)) used CXCR4 almost exclusively

Zebrafish Chemokine (C-X-C Motif) Receptor 4 (CXCR4) interaction partners

  1. Arteries are formed by vein-derived endothelial tip cells, this process critically depends on chemokine receptor Cxcr4 function.

  2. SDF1a (show CXCL12 Antibodies) directly controls the migration of both leading and trailing edges of a tissue through the activation of two independent receptors, CXCR4b and CXCR7 (show CXCR7 Antibodies).

  3. Hoxb8a is induced by and cooperates with Wnt (show WNT2 Antibodies) signaling to up-regulate cxcr4b, and acts through multiple mechanisms to repress cxcr7b expression.

  4. Expression of Cxcr4 and Cxcl12 (show CXCL12 Antibodies) in radial glial cells of the adult zebrafish brain supports important roles for the Cxcl12 (show CXCL12 Antibodies)/Cxcr4 pair in brain development and functioning.

  5. show that inactivation of the estrogen receptor ESR1 (show ESR1 Antibodies) results in ectopic expression of cxcr4b throughout the primordium, whereas ESR1 (show ESR1 Antibodies) overexpression results in a reciprocal reduction in the domain of cxcr4b expression.

  6. Study suggest that the Cxcl12a-Cxcr4b ligand-receptor pair are involved in the migration of GnRH3 neurons in zebrafish, and are therefore crucial for the development of this system.

  7. A CXCR4-like chemokine receptor (show CCR1 Antibodies) is expressed by the migrating lateral line primordium cells. Both the formation and the innervation of this system depend on the SDF1 (show CXCL12 Antibodies)-CXCR4 system.

  8. Knocking down CXCR4 results in severe defects in primordial germ cell migration.

  9. SDF-1 (show CXCL12 Antibodies)/CXCR4 signaling is important for guiding retinal ganglion cell axons within the retina to the optic stalk to exit the retina.

  10. chemokine (show CCL1 Antibodies) signaling contributes to both the olfactory placode assembly and the olfactory sensory neurons axon pathfinding in zebrafish

CXCR4 Antigen Profile

Antigen Summary

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Alternative names and synonyms associated with CXCR4

  • chemokine (C-X-C motif) receptor 4 (cxcr4) antibody
  • chemokine (C-X-C motif) receptor 4 (CXCR4) antibody
  • chemokine (C-X-C motif) receptor 4 (Cxcr4) antibody
  • chemokine (C-X-C motif) receptor 4 (cxcr4-b) antibody
  • chemokine (C-X-C motif), receptor 4b (cxcr4b) antibody
  • neuropeptide Y receptor type 3 (CXCR4) antibody
  • cb403 antibody
  • CD184 antibody
  • Cmkar4 antibody
  • CXC-R4 antibody
  • CXC-R4-B antibody
  • CXCR-4 antibody
  • CXCR-4-B antibody
  • CXCR4 antibody
  • D2S201E antibody
  • FB22 antibody
  • HM89 antibody
  • HSY3RR antibody
  • LAP3 antibody
  • LCR1 antibody
  • LESTR antibody
  • NPY3R antibody
  • NPYR antibody
  • NPYRL antibody
  • NPYY3R antibody
  • PB-CKR antibody
  • PBSF/SDF-1 antibody
  • Sdf1r antibody
  • WHIM antibody
  • xcxcr4 antibody
  • zgc:109863 antibody

Protein level used designations for CXCR4

C-X-C chemokine receptor type 4 , SDF-1 receptor , Stromal cell-derived factor 1 receptor , chemokine (C-X-C motif) receptor 4 , CXC-R4 , CXCR-4 , chemokine (C-X-C) receptor 4 , chemokine receptor 4 , fusin , leukocyte-derived seven transmembrane domain receptor , leukocyte-expressed seven-transmembrane-domain , pre-B-cell-derived chemokine receptor , stromal cell-derived factor 1 receptor , CXC chemokine receptor , LESTR , chemokine receptor (LCR1) , CD184 antigen , leukocyte-derived seven-transmembrane-domain receptor , lipopolysaccharide-associated protein 3 , neuropeptide Y receptor Y3 , seven transmembrane helix receptor , seven-transmembrane-segment receptor, spleen , C-X-C chemokine receptor type 4-B , SDF-1 receptor B , SDF-1 receptor-B , Stromal cell-derived factor 1 receptor-B , stromal cell-derived factor 1 receptor B , LCR1 , chemokine receptor CXCR4 , CXC chemokine receptor 4 , ody , odysseus

GENE ID SPECIES
100038176 Xenopus (Silurana) tropicalis
100049444 Oryzias latipes
100346189 Oryctolagus cuniculus
100451032 Pongo abelii
100604120 Nomascus leucogenys
12767 Mus musculus
60628 Rattus norvegicus
7852 Homo sapiens
396659 Sus scrofa
380373 Xenopus laevis
281736 Bos taurus
493676 Felis catus
483900 Canis lupus familiaris
707329 Macaca mulatta
395324 Gallus gallus
100126711 Papio anubis
450130 Pan troglodytes
114447 Danio rerio
443532 Ovis aries
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