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anti-Human Netrin 1 Antibodies:
anti-Mouse (Murine) Netrin 1 Antibodies:
anti-Rat (Rattus) Netrin 1 Antibodies:
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Mouse (Murine) Monoclonal Netrin 1 Primary Antibody for ELISA, WB - ABIN269526
Goshima, Ito, Sasaki, Nakamura: Semaphorins as signals for cell repulsion and invasion. in The Journal of clinical investigation 2002
Show all 7 Pubmed References
Human Polyclonal Netrin 1 Primary Antibody for WB - ABIN1881590
Meyerhardt, Caca, Eckstrand, Hu, Lengauer, Banavali, Look, Fearon: Netrin-1: interaction with deleted in colorectal cancer (DCC) and alterations in brain tumors and neuroblastomas. in Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1999
Show all 5 Pubmed References
Human Polyclonal Netrin 1 Primary Antibody for ICC, IF - ABIN151152
Manitt, Labelle-Dumais, Eng, Grant, Mimee, Stroh, Flores: Peri-pubertal emergence of UNC-5 homologue expression by dopamine neurons in rodents. in PLoS ONE 2010
Show all 4 Pubmed References
Human Polyclonal Netrin 1 Primary Antibody for WB - ABIN3044248
Zhong, Zou, Zhao, Hu, Xie: Effect of different concentrations of neogenin on proliferation, apoptosis and related proliferative factors in human trophoblasts. in Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2010
Show all 2 Pubmed References
Chicken Monoclonal Netrin 1 Primary Antibody for ELISA, IHC - ABIN4338687
Manitt, Nikolakopoulou, Almario, Nguyen, Cohen-Cory: Netrin participates in the development of retinotectal synaptic connectivity by modulating axon arborization and synapse formation in the developing brain. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2009
Show all 2 Pubmed References
Rat (Rattus) Polyclonal Netrin 1 Primary Antibody for ELISA, WB - ABIN335150
Jayakumar, Nauta, Bakker, Bilo, Gansevoort, Johnson, Ramesh: Netrin-1, a urinary proximal tubular injury marker, is elevated early in the time course of human diabetes. in Journal of nephrology 2014
Show all 2 Pubmed References
Human Polyclonal Netrin 1 Primary Antibody for IF, IHC - ABIN187960
Ramesh, Berg, Jayakumar: Plasma netrin-1 is a diagnostic biomarker of human cancers. in Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2011
Human Polyclonal Netrin 1 Primary Antibody for ELISA, WB - ABIN4338686
Lin, Rao, Isacson: Netrin-1 and slit-2 regulate and direct neurite growth of ventral midbrain dopaminergic neurons. in Molecular and cellular neurosciences 2005
our data suggest that netrin-1 contributes to the migration of the neural folds towards the midline
Partial knock down of netrin-1 confirms that this chemoattractive ligand of neogenin (show NEO1 Antibodies) acts in the same early forming dorsoventral brain pathway.
Studies identify netrin-1 as an active participant in retinal ganglion cell axon presynaptic differentiation, not only as they navigate along their pathway but also at their target.
Netrin-1 acts as a non-canonical angiogenic factor (show VEGFA Antibodies) produced by human Wharton's jelly mesenchymal stem cells.
Our study has shown an increase in netrin-1 expression that could be linked with macrophage infiltration and polarization in the epicardial adipose tissue of patients with coronary artery disease
netrin-1 degradation products are capable of modulating vascular permeability in diabetic retinopathy
Enhanced detection of netrin-1-expressing CD14(low) cells in patients with systemic sclerosis-related interstitial lung disease was observed, and antibody-mediated netrin-1 neutralization attenuated detection of fibrocytes in all settings.
we review the Netrin-1 mediated regulation of cancer, its potential use as a biomarker, and the targeting of the Netrin-1 pathway to treat cancers
Our observations revealed that SOX6 is a tumor suppressor in ovarian cancer cells, and SOX6 exerts an inhibitory effect on the proliferation, invasion, and tumor cell-induced angiogenesis of ovarian cancer cells, whereas nerin-1 plays an opposite role and its expression is inversely correlated with SOX6.
NTN1 rs9788972 is identified as a risk locus for nonsyndromic orofacial clefts susceptibility in a northern Chinese population; SNPs in PAX7 (show PAX7 Antibodies) were not associated with any increased risk
that netrin-1 may function as a positive regulator of hypoxia-triggered malignant behavior in prostate cancer by activating the Yes-associated protein signaling
Data suggest that urinary netrin-1 may be a new biomarker for determining early tubular injury in obese children.
cell proliferation and survival were decreased following targeted deletion of Netrin-1. Cell invasion was dramatically diminished in Netrin-1 knockdown Glioblastoma stem cells. Moreover, Netrin-1 knockdown Glioblastoma stem cells exhibited less proangiogenic activity.
Ntn1 may play divergent cellular roles despite its conserved expression during canal morphogenesis in chicken and mouse.
Blockade of Netrin-1/Unc5b (show UNC5B Antibodies) by monoclonal antibodies prevents bone destruction and reduces the severity of K/BxN serum transfer-induced arthritis
Results suggest that Netrin1/DCC (show DCC Antibodies) signaling induce neuronal migration in the dorsal spinal cord.
results show that the classical view that attraction of commissural axons is mediated by a gradient of floor-plate-derived netrin-1 is inaccurate and that netrin-1 primarily acts locally by promoting growth cone adhesion.
Here, we report that dissociation of UNC5C (show Unc5c Antibodies) and polymerized TUBB3 (show TUBB3 Antibodies), the highly dynamic beta-tubulin (show TUBB Antibodies) isoform in neurons, is essential for netrin-1/UNC5C (show Unc5c Antibodies)-promoted axon repulsion. These results not only provide a working model of direct modulation of MTs (show NEU2 Antibodies) by guidance cues in growth cone navigation but also help us to understand molecular mechanisms underlying developmental brain disorders associated with TUBB3 (show TUBB3 Antibodies) mutations.
Netrin-1(+/-) mice were protected against bleomycin-induced lung fibrosis and fibrocyte accumulation.
Netrin-1 enhanced insulin (show INS Antibodies) secretion by promoting beta-cell Ca(2 (show CA2 Antibodies)+) influx and cAMP production.
netrin 1 treatment prevented bone erosion in an autoimmune arthritis model and age-related bone destruction.
Netrin-1 reduced the Abeta1- 40-induced Abeta1-42 increase, increased sAbetaPPalpha, and reversed the Abeta (show APP Antibodies)-induced sAbetaPPalpha decrease in vitro; in vivo, induction of netrin-1 expression in PDAbetaPPSwe/Ind transgenic mice resulted in reductions in both Abeta1-42 and Abeta1- 40, and ICV delivery of netrin-1 to PDAbetaPPSwe/Ind mice increased sAbetaPPalpha, decreased Abeta (show APP Antibodies), and improved working memory.
Treatment with endogenous anti-inflammatory protein netrin-1 reduces pulmonary inflammation during the initial stages of acute lung injury.
Netrin-1 could be important for follicular function in the swine.
findings show that the netrin-1 and p53RDL1 (show UNC5B Antibodies) system may regulate the induction of apoptosis in porcine granulosa cells
Netrin is included in a family of laminin-related secreted proteins. The function of this gene has not yet been defined\; however, netrin is thought to be involved in axon guidance and cell migration during development. Mutations and loss of expression of netrin suggest that variation in netrin may be involved in cancer development.
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, netrin 1, mouse, homolog of