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Browse our RGS8 Proteins (RGS8)

Full name:
Regulator of G-Protein Signaling 8 Proteins (RGS8)
On are 8 Regulator of G-Protein Signaling 8 (RGS8) Proteins from 4 different suppliers available. Additionally we are shipping RGS8 Antibodies (39) and many more products for this protein. A total of 51 RGS8 products are currently listed.
6530413N01Rik, zgc:92913
list all proteins Gene Name GeneID UniProt
RGS8 85397 P57771
RGS8 67792 Q8BXT1
RGS8 54297 P49804

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RGS8 Proteins (RGS8) by Origin

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More Proteins for RGS8 Interaction Partners

Human Regulator of G-Protein Signaling 8 (RGS8) interaction partners

  1. The chimeric RGS8 domains containing the first or the second exon part of RGS5 (show RGS5 Proteins) showed strong inhibitory effects similar to that of wild type RGS8, but the chimeric domain with the third exon part of RGS5 (show RGS5 Proteins) lost its activity

  2. Missense mutations in RGS8 gene is associated with breast cancer.

  3. Spinophilin (show PPP1R9B Proteins) was identified as an RGS8-interacting protein.

Mouse (Murine) Regulator of G-Protein Signaling 8 (RGS8) interaction partners

  1. the crystal structure of RGS8 was determined in complex with Galphaq (show GNAQ Proteins).

  2. ATXN2 (show ATXN2 Proteins) interacted selectively with RGS8 mRNA. This interaction was impaired when ATXN2 (show ATXN2 Proteins) harbored an expanded polyglutamine. Mutant ATXN2 (show ATXN2 Proteins) also reduced RGS8 expression in an in vitro coupled translation

  3. increased miR (show MLXIP Proteins)-150 levels in Spinocerebellar ataxia (show USP14 Proteins) type 1 Purkinje neurons may modulate disease pathogenesis by targeting the expression of Rgs8 and Vegfa (show VEGFA Proteins).

  4. RGS8 null mutant mice were viable, fertile and showed apparently normal development

RGS8 Protein Profile

Protein Summary

This gene is a member of the regulator of G protein signaling (RGS) family and encodes a protein with a single RGS domain. Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. They accelerate transit through the cycle of GTP binding and hydrolysis to GDP, thereby terminating signal transduction, but paradoxically, also accelerate receptor-stimulated activation.

Alternative names and synonyms associated with RGS8

  • regulator of G-protein signaling 8 (RGS8)
  • regulator of G-protein signaling 8 (Rgs8)
  • regulator of G-protein signaling 8 (rgs8)
  • 6530413N01Rik protein
  • zgc:92913 protein

Protein level used designations for RGS8

regulator of G-protein signalling 8

85397 Homo sapiens
490311 Canis lupus familiaris
781543 Bos taurus
67792 Mus musculus
54297 Rattus norvegicus
436804 Danio rerio
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