Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all synonyms
Select your origin of interest
Human BMP2 Protein expressed in Escherichia coli (E. coli) - ABIN2017696
Sampath, Coughlin, Whetstone, Banach, Corbett, Ridge, Ozkaynak, Oppermann, Rueger: Bovine osteogenic protein is composed of dimers of OP-1 and BMP-2A, two members of the transforming growth factor-beta superfamily. in The Journal of biological chemistry 1990
Show all 18 Pubmed References
Human BMP2 Protein expressed in Escherichia coli (E. coli) - ABIN1589575
Suliman, Xing, Wu, Xue, Pedersen, Sun, Døskeland, Nickel, Waag, Lygre, Finne-Wistrand, Steinmüller-Nethl, Krueger, Mustafa: Release and bioactivity of bone morphogenetic protein-2 are affected by scaffold binding techniques in vitro and in vivo. in Journal of controlled release : official journal of the Controlled Release Society 2014
Show all 5 Pubmed References
Human BMP2 Protein expressed in Escherichia coli (E. coli) - ABIN413080
Sharapova, Kotnova, Galushkina, Lavrova, Poletaeva, Tukhvatulin, Tukhvatullin, Semikhin, Gromov, Soboleva, Ershova, Za?tsev, Sergienko, Lunin, Kariagina: [Production of the recombinant human bone morphogenetic protein-2 in Escherichia coli and testing of its biological activity in vitro and in vivo]. in Molekuliarnaia biologiia 2011
Show all 4 Pubmed References
Human BMP2 Protein expressed in Escherichia coli (E. coli) - ABIN2002823
Wozney, Rosen, Celeste, Mitsock, Whitters, Kriz, Hewick, Wang: Novel regulators of bone formation: molecular clones and activities. in Science (New York, N.Y.) 1989
Show all 5 Pubmed References
Results identify a novel 4671-bp tandem duplication downstream of BMP2, which is associated with brachydactyly type A2 . The duplication highly overlaps the sequences reported previously but has a different breakpoint and a different flanking microhomology.
miR (show MLXIP Proteins)-106b inhibited osteoblastic differentiation and bone formation partly through directly targeting bone morphogenetic protein 2.
BMP2 decreases gap junction intercellular communication of luteinized human granulosa cells by downregulating Cx43 (show GJA1 Proteins) expression through an ALK2 (show ACRV1 Proteins)/ALK3 (show BMPR1A Proteins)-mediated SMAD (show SMAD1 Proteins)-dependent signaling pathway.
BMP2 also requires Src (show SRC Proteins) for filamentous actin polymerization in Tgfbr3 (show TGFBR3 Proteins)(-/-) epicardial cells.
The deletion contained 17 protein coding genes including PROKR2 (show PROKR2 Proteins) and BMP2, both of which are expressed during embryological development of the pituitary gland. PROKR2 (show PROKR2 Proteins) mutations have been associated with hypopituitarism but a heterozygous deletion of this gene with hypopituitarism is a novel observation.
both bone morphogenetic protein 2 (BMP2) and BMP6 (show BMP6 Proteins) are proangiogenic in vitro and ex vivo and that the BMP type I receptors, activin receptor-like kinase 3 (ALK3 (show BMPR1A Proteins)) and ALK2 (show ACRV1 Proteins), play crucial and distinct roles in this process.
sequential presentation of PDGF (show PDGFA Proteins) to BMP-2 led to increased tubule formation over simultaneous delivery of these growth factors.
Bone Morphogenetic Protein-2, But Not Mesenchymal Stromal Cells, Exert Regenerative Effects on Canine and Human Nucleus Pulposus Cells
The structure of Grem2 (show GREM2 Proteins)-GDF5 (show GDF5 Proteins) complex has revealed a number of key findings for DAN-family mediated BMP2 inhibition.
Bioluminescence imaging reveals increased MSC (show MSC Proteins) survival when implanted in BMP-2 PAHs.
Dual luciferase report assay verified that miR (show MLXIP Proteins)-3065-5p could bind to the 3'UTR of bone morphogenetic protein receptor type II (BMPR2 (show BMPR2 Proteins)), which dramatically increased in the beginning of odontoblastic differentiation but decreased in the terminal differentiation stage.
increased BMPR2 (show BMPR2 Proteins) signal transduction is linked to fragile X (show FMR1 Proteins) syndrome (FXS) and that the BMPR2 (show BMPR2 Proteins)-LIMK1 (show LIMK1 Proteins) pathway is a putative therapeutic target in patients with FXS and possibly other forms of autism
cells stimulated with BMP-2 in the presence of FBS (show FBS Proteins) require the phosphorylation of Akt (show AKT1 Proteins) at Ser473 and the dephosphorylation of Akt (show AKT1 Proteins) at Thr308 to increase the osteoblast differentiation with alkaline phosphatase activity similar to that of BMP-9 (show GDF2 Proteins) plus FBS (show FBS Proteins).
This study showed that release of BMP-2 and SDF-1alpha from heparinized MCM scaffolds allows for the reduction of the applied BMP-2 concentration since SDF-1alpha seems to enhance the osteoinductive potential of BMP-2.
mice implanted with sulfonated PRX (show PRX Proteins)/BMP-2 complexes exhibited rapid and significant bone regeneration compared to those implanted with free BMP-2 and heparin/BMP-2 complexes.
these data demonstrate that in addition to BMP6 (show BMP6 Proteins), endothelial cell BMP2 has a non-redundant role in hepcidin (show HAMP Proteins) regulation by iron.
results indicate that Alx3 (show ALX3 Proteins) expression is enhanced by BMP-2 via the BMP receptors mediated-Smad (show SMAD1 Proteins) signaling and that Alx3 (show ALX3 Proteins) is a positive regulator of osteoblast differentiation induced by BMP-2
KDM5A (show KDM5A Proteins)-mediated H3K4me3 modification participated in the etiology of osteoporosis and may provide new strategies to improve the clinical efficacy of BMP2 in osteoporotic conditions.
BMP2 expression in the endocardial lineage is essential for the distal outgrowth, maturation and remodeling of atrioventricular endocardial cushions.
Bone morphogenetic protein inhibition is sufficient for neural induction in vivo, and that in the absence of ventral BMPs, Spemann organizer signals are not required for brain formation.
Bmp antagonists and morpholinos designed against Bmp4, Bmp2, and Bmp7 demonstrate that Bmp signaling is critical for ventral, but not dorsoanterior endoderm formation
High BMP2 expression is associated with cystic ovarian disease.
both FSH (show BRD2 Proteins) and BMP-2 reduced follicular mRNA expression of GDF9 (show GDF9 Proteins) and NLRP5 when compared to follicles cultured in media containing only FSH (show BRD2 Proteins)
The BMP2/4 (show BMP4 Proteins) ligand and receptor system presides within bovine trophectoderm prior to uterine attachment.
concluded that a bone morphogenetic protein (BMP)-signaling system, consisting of BMP2, BMP4, type II and I receptors, is present in bovine antral follicles and plays a role in development and functioning of follicles rather than oocyte maturation
The transfecting capability of a BMP-2 specific vector is examined and supports the idea that BMP-2 might diminish osseointegration and implant fixation.
While BMP2 expression begins at (pregastrulation) stage 1 in the hypoblast, BMP4 (show BMP4 Proteins) expression commences--distinctly delayed compared to the mouse--diffusely at (pregastrulation) stage 2; from stage 3 onwards.
Maxillary sinus floor elevation using BMP-2 gene-modified bone marrow stromal cells and TCP in rabbits
Data show that BMP-2, BMP-4 (show BMP4 Proteins), and BMP-7 (show BMP7 Proteins), noggin (show NOG Proteins), and chordin (show CHRD Proteins) were colocalized in rimming osteoblasts, osteoclasts, and chondrocytes.
BMP2 is not suitable to regenerate osteochondral lesions completely
High yield isolation of BMP-2 from bone and in vivo activity of a combination of BMP-2/TGF-beta1 (show TGFB1 Proteins).
Report temporal regulation of BMP2 mRNA expression in the oocyte, granulosa and theca cells of developing preovulatory follicles in the pig.
Regional variation of periosteal activity at the mandibular ramus is regulated by differential induction of BMP2.
The effects of soy- and cow's milk-based formulas compared to nursing on bone development through BMP2 expression in neonatal pigs are reported.
The effect of bone morphogenetic protein (BMP) 12 and BMP2 expression on differentiation of bone marrow-derived mesenchymal stem cells and superficial digital flexor tenocytes is reported.
Study found that BMP-2 (show BMP4 Proteins) is negatively regulated by miR (show MYLIP Proteins)-140 during early embryogenesis and bone development in zebra fi sh.
Structures of Bmp2a, Bmp2b (show BMP4 Proteins), Bmp4 (show BMP4 Proteins) and Bmp16 were found to be remarkably similar; with residues involved in receptor binding being highly conserved.
bmp2a is a crucial player in the specification of the ventral pancreatic bud in zebrafish embryos.
results indicate that both the induction of a photoreceptor fate and the interaction with Notch (show NOTCH1 Proteins) relies on a canonical BMP/Smad5 (show SMAD5 Proteins) pathway
Mypt1 (show PPP1R12A Proteins) mediates coordination between mesoderm and endoderm cell movements in order to carefully position the liver primordium such that it receives a Bmp2 (show BMP4 Proteins) signal that is essential for liver formation
The protein encoded by this gene belongs to the transforming growth factor-beta (TGFB) superfamily. The encoded protein acts as a disulfide-linked homodimer and induces bone and cartilage formation.
, bone morphogenetic protein 2A
, BMP type II receptor
, BMP type-2 receptor
, bone morphogenetic protein receptor type-2
, bone morphogenic protein receptor, type II (serine/threonine kinase)
, bone morphogenetic protein 2 B
, bone morphogenetic protein 2-B
, bone morphogenetic protein 2
, Bone morphogenetic protein 2
, bone morphogenetic protein 2-like
, bone morphogenetic protein 2 precursor (BMP-2) (BMP-2A)