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Browse our Luteinizing Hormone/choriogonadotropin Receptor Proteins (LHCGR)

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Luteinizing Hormone/choriogonadotropin Receptor Proteins (LHCGR)
On are 20 Luteinizing Hormone/choriogonadotropin Receptor (LHCGR) Proteins from 2 different suppliers available. Additionally we are shipping Luteinizing Hormone/choriogonadotropin Receptor Antibodies (170) and Luteinizing Hormone/choriogonadotropin Receptor Kits (10) and many more products for this protein. A total of 201 Luteinizing Hormone/choriogonadotropin Receptor products are currently listed.
CDW44, CSPG8, ECMR-III, Gpcr19-rs1, GTHR-II, HCELL, HHG, HUTCH-I, IN, LCGR, LGR2, LH-R, LH/CG-R, LH/CGR, LHCGR, Lhr, LHRHR, LOC100222883, LOC100305044, LSH-R, LSHR, MC56, MDU2, MDU3, MIC4, Pgp1, ULG5, zfGTHR-II
list all proteins Gene Name GeneID UniProt
LHCGR 960 P16070
LHCGR 16867 P30730
LHCGR 25477 P16235

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Luteinizing Hormone/choriogonadotropin Receptor Proteins (LHCGR) by Origin

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More Proteins for Luteinizing Hormone/choriogonadotropin Receptor Interaction Partners

Zebrafish Luteinizing Hormone/choriogonadotropin Receptor (LHCGR) interaction partners

  1. Data show that double mutation of follicle-stimulating hormone receptor (fshr (show FSHR Proteins)) and luteinizing hormone receptor (lhcgr) resulted in infertile males

  2. Data show for the first time in a vertebrate species that Leydig cells as well as Sertoli cells express the mRNAs for both fshr (show FSHR Proteins) and lhcgr.

Horse (Equine) Luteinizing Hormone/choriogonadotropin Receptor (LHCGR) interaction partners

Human Luteinizing Hormone/choriogonadotropin Receptor (LHCGR) interaction partners

  1. CD44 (show CD44 Proteins) expression in head and neck squamous cell carcinoma plays a role in enhancing the DNA damage response

  2. cells depleted of cholesterol had higher membrane fluidity, and more uniform distribution of CD44 (show CD44 Proteins) counterreceptor, which resulted in smooth motion of the cells compared to cells enriched with cholesterol.

  3. These results support the feasibility of an adenovirus-mediated RNA interference therapy targeting human colon cancer via the CD44 (show CD44 Proteins) as a potential future therapeutic intervention.

  4. CD44 (show CD44 Proteins) was overexpressed in NSCLC and the overexpression was associated with the occurrence of NSCLC and migration of NSCLC cells.

  5. EpCAM, CD44 and CD133 expression could be candidate markers for Barrett esophagus disease progression

  6. Study demonstrated the expression of CD44 (show CD44 Proteins) was upregulated in breast cancer and was closely correlated with high grade.

  7. Authors validated CD44 (show CD44 Proteins) to be the direct gene via luciferase reporter assay system. We also established the negative regulatory relationship between miR (show MLXIP Proteins)-328 and CD44 (show CD44 Proteins). miR (show MLXIP Proteins)-328 was also recognized as a potential biomarker to predict recurrence after Endoscopic Submucosal Dissection in Early Gastric Cancer patients via analysis of the recurrence-free rate among different groups of Early Gastric Cancer patients.

  8. expression and activation of LHCGR and ARF6 (show ARF6 Proteins) are up-regulated in GC from PCOS women but the mechanism of agonist-induced LHCGR internalization is unaltered

  9. CD44 and CD133 expression status prior to treatment dictates the malignant potential of esophageal squamous cell carcinoma (ESCC) and may be a novel predictor of recurrence and prognosis of ESCC patients after treatment.

  10. The subgroup of patients with double expression of MMP-14 (show MMP14 Proteins) and CD44 (show CD44 Proteins) had a poor prognosis despite complete debulking. Serous subtype in advanced-stage patients and CD44 (show CD44 Proteins) expression were found to be correlated with vimentin (show VIM Proteins) expression, and CD44 (show CD44 Proteins) expression was found to be significantly correlated with complete debulking

Mouse (Murine) Luteinizing Hormone/choriogonadotropin Receptor (LHCGR) interaction partners

  1. FSHR (show FSHR Proteins) and LHR proteins are significantly upregulated in CCs (show CCS Proteins) surrounding oocytes arrested at the 2-cell stage, reflecting their developmental incompetence.

  2. Triptorelin and cetrorelix induce immune responses and affect uterine development and expressions of genes and proteins of ESR1 (show ESR1 Proteins), LHR, and FSHR (show FSHR Proteins)

  3. Data suggest that persistent cAMP signals from internalized luteinizing hormone receptor (LH receptors) contribute to transmitting LH effects inside follicle cells and ultimately to the oocyte.

  4. Demonstrate the presence of LH receptors. Activation resulted in a dose-dependent increase in glucose-induced release of insulin (show INS Proteins).

  5. LHCGR signaling in regulating the Ahr (show AHR Proteins) message involves protein kinase A pathway and is attributable to decreased transcription rate.

  6. Data from mutant mouse strain (gain-of-function mutation in LHR, D578G; most common mutation found in familial male-limited precocious puberty) confirm that LHR is critical for male steroidogenesis, gametogenesis, and Leydig cell development.

  7. LH/hCG (show CGA Proteins) tightly up-regulates MKP-3 (show DUSP6 Proteins) which in turn, dephosphorylates ERK1/2 and drives p21 expression.

  8. Data suggest that Lhcgr in endometrium and luteinizing hormone in blastocyst are involved in embryo/blastocyst implantation; expression of Lhcgr is up-regulated in endometrial epithelium in estrus cycle at time of implantation readiness (estrus).

  9. Through the LHR, LH/hCG (show CGA Proteins) tightly regulates MKP-2 (show DUSP4 Proteins) expression, which modulates the induction of CYP11A1 (show CYP11A1 Proteins) by 8Br-cAMP.

  10. Expression of LH receptor in nonpregnant mouse endometrium.

Cow (Bovine) Luteinizing Hormone/choriogonadotropin Receptor (LHCGR) interaction partners

  1. The outcomes of the present study support a dynamic multi-facetted regulation of LHR during pre-translation.

  2. expression of LHR mRNA in bovine granulosa cells is established after follicle deviation, and the lower abundance of LRBP (show MVK Proteins) mRNA after the expected time of deviation may contribute to greater expression of LHR in the bovine dominant follicle

  3. These results suggested an acute regulation of INSL3 (show INSL3 Proteins) by luteinizing hormone (LH) because INSL3 (show INSL3 Proteins) concentrations increased immediately after endogenous and exogenous LH stimulation.


  5. These findings strongly support the concept that IGF-1 (show IGF1 Proteins) upregulates LHR expression in granulosa cells and that IGF-1 (show IGF1 Proteins) is required for determining which follicle becomes dominant and acquires ovulatory capacity.

  6. LHCGR mRNA expression in granulosa cells was significantly higher in large antral follicles than in cysts, and not detected in granulosa cells of small and medium antral follicles.

  7. The luteinizing hormone receptor [LHR] splicing pattern is complex in bovine Leydig cells, and expression of full-length LHR and isoforms A and B changes when induced with LH.

  8. The LHCGR gene is a potential marker for superovulation response and can be used to predict the most appropriate dose of FSH (show BRD2 Proteins) for superovulation in Chinese Holstein cows.

  9. Dominant follicles experience a reduction in FSH (show BRD2 Proteins) dependence (diminished expression of FSHR (show FSHR Proteins)), but acquire increased LH dependence (enhanced expression of LHCGR) as they grow during the low FSH (show BRD2 Proteins) milieu of follicular waves.

  10. Three single nucleotide polymorphisms in LHCGR were significantly associated with variations in cattle fertility and production traits.

Pig (Porcine) Luteinizing Hormone/choriogonadotropin Receptor (LHCGR) interaction partners

  1. In porcine ovaries, MAb found 6 distinct LHR bands migrating at approximately 92, 80, 68, 59, 52 & 48 kDa. There is a possible role for LHR in the development of abnormal pregnancy, pelvic floor disorders & Alzheimer's disease.

Luteinizing Hormone/choriogonadotropin Receptor (LHCGR) Protein Profile

Protein Summary

This gene encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia.

Alternative names and synonyms associated with Luteinizing Hormone/choriogonadotropin Receptor (LHCGR)

  • luteinizing hormone/choriogonadotropin receptor (lhcgr-A)
  • luteinizing hormone/choriogonadotropin receptor (lhcgr)
  • luteinizing hormone/choriogonadotropin receptor (LHCGR)
  • luteinizing hormone/choriogonadotropin receptor (LOC100222883)
  • luteinizing hormone receptor (LHR)
  • luteinizing hormone receptor (lhr)
  • luteinizing hormone receptor (LOC100305044)
  • CD44 molecule (Indian blood group) (CD44)
  • luteinizing hormone/choriogonadotropin receptor (Lhcgr)
  • CDW44 protein
  • CSPG8 protein
  • ECMR-III protein
  • Gpcr19-rs1 protein
  • GTHR-II protein
  • HCELL protein
  • HHG protein
  • HUTCH-I protein
  • IN protein
  • LCGR protein
  • LGR2 protein
  • LH-R protein
  • LH/CG-R protein
  • LH/CGR protein
  • LHCGR protein
  • Lhr protein
  • LHRHR protein
  • LOC100222883 protein
  • LOC100305044 protein
  • LSH-R protein
  • LSHR protein
  • MC56 protein
  • MDU2 protein
  • MDU3 protein
  • MIC4 protein
  • Pgp1 protein
  • ULG5 protein
  • zfGTHR-II protein

Protein level used designations for LHCGR

luteinizing hormone receptor , lutropin-choriogonadotropic hormone receptor , luteinizing hormone/choriogonadotropin receptor , lutropin-choriogonadotropic hormone receptor-like , Lutropin-choriogonadotropic hormone receptor , CD44 antigen , GP90 lymphocyte homing/adhesion receptor , Hermes antigen , cell surface glycoprotein CD44 , chondroitin sulfate proteoglycan 8 , epican , extracellular matrix receptor III , hematopoietic cell E- and L-selectin ligand , heparan sulfate proteoglycan , homing function and Indian blood group system , hyaluronate receptor , phagocytic glycoprotein 1 , hypergonadotropic hypogonadism , lutropin/choriogonadotropin receptor , LH/CG-R , LSH-R , LH receptor , luteinizing hormone receptor 2 protein , luteinizing hormone receptor precursor variant 1 , luteinizing hormone receptor precursor variant 2 , lutropin-choriogonadotropin receptor

378624 Xenopus laevis
402920 Danio rerio
481365 Canis lupus familiaris
715999 Macaca mulatta
100034043 Equus caballus
100222883 Taeniopygia guttata
100303684 Meleagris gallopavo
100380984 Xenopus laevis
100457164 Pongo abelii
443339 Ovis aries
100135989 Oncorhynchus mykiss
100136406 Salmo salar
100305044 Ictalurus punctatus
100529183 Oryzias latipes
100583593 Nomascus leucogenys
100615277 Pan troglodytes
960 Homo sapiens
3973 Homo sapiens
16867 Mus musculus
25477 Rattus norvegicus
281900 Bos taurus
395776 Gallus gallus
407247 Sus scrofa
101113228 Ovis aries
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