Browse our anti-CADM1 (CADM1) Antibodies

Full name:
anti-Cell Adhesion Molecule 1 Antibodies (CADM1)
On www.antibodies-online.com are 115 Cell Adhesion Molecule 1 (CADM1) Antibodies from 26 different suppliers available. Additionally we are shipping CADM1 Proteins (15) and CADM1 Kits (8) and many more products for this protein. A total of 149 CADM1 products are currently listed.
Synonyms:
2900073G06Rik, 3100001I08Rik, AI987920, Bl2, Igsf4, Igsf4a, Necl-2, Necl2, RA175, RA175A, RA175B, RA175C, RA175N, SgIGSF, ST17, sTSLC-1, SynCam, synCAM1, Tslc1, xnecl2
list all antibodies Gene Name GeneID UniProt
CADM1 445438  
CADM1 23705 Q9BY67
CADM1 54725 Q8R5M8

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anti-Mouse (Murine) CADM1 Antibodies:

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Top referenced anti-CADM1 Antibodies

  1. Human Polyclonal CADM1 Primary Antibody for EIA, IHC (p) - ABIN951001 : McGovern, Jones, Taylor, Marciante, Yan, Dubinsky, Ippoliti, Vasiliauskas, Berel, Derkowski, Dutridge, Fleshner, Shih, Melmed, Mengesha, King, Pressman, Haritunians, Guo, Targan, Rotter: Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease. in Human molecular genetics 2010 (PubMed)
    Show all 5 references for 951001

  2. Human Polyclonal CADM1 Primary Antibody for IF (p), IHC (p) - ABIN738351 : Liu, Cui, Ao, Zhou, Zhou, Yuan, Xiang, Liu, Cao et al.: Aberrant methylation accounts for cell adhesion-related gene silencing during 3-methylcholanthrene and diethylnitrosamine induced multistep rat lung carcinogenesis associated with overexpression of ... in Toxicology and applied pharmacology 2011 (PubMed)
    Show all 2 references for 738351

  3. Human Polyclonal CADM1 Primary Antibody for ICC, IF - ABIN152528 : Biederer, Sara, Mozhayeva, Atasoy, Liu, Kavalali, Südhof: SynCAM, a synaptic adhesion molecule that drives synapse assembly. in Science (New York, N.Y.) 2002 (PubMed)
    Show all 2 references for 152528

  4. Human Polyclonal CADM1 Primary Antibody for IHC, ELISA - ABIN1585332 : Ballester, Gonin, Rodenas, Bernaudin, Rouzier, Coutant, Daraï: Eutopic endometrium and peritoneal, ovarian and colorectal endometriotic tissues express a different profile of nectin-1, -3, -4 and nectin-like molecule 2. in Human reproduction (Oxford, England) 2012 (PubMed)

  5. Human Polyclonal CADM1 Primary Antibody for IHC (p), WB - ABIN654660 : Shimada, Miyagawa, Kawashima, Tanaka, Honda, Honda, Tokunaga: An approach based on a genome-wide association study reveals candidate loci for narcolepsy. in Human genetics 2010 (PubMed)

More Antibodies against CADM1 Interaction Partners

Human Cell Adhesion Molecule 1 (CADM1) interaction partners

  1. CADM1 mRNA expression was highly upregulated in normal tissues compared to esophageal squamous cell carcinoma tissues, indicating that the loss of CADM1 expression influenced the pathogenesis, invasion, and metastasis of ESCC.

  2. Eight and five of the nine samples were negative for cell adhesion molecule 1 and Osterix (show SP7 Antibodies) respectively. The other markers showed no statistical significance(CD151 (show CD151 Antibodies),ALP (show ALP Antibodies)). osteoblastic differentiation can occur in carcinoma cells and that cell adhesion molecule 1 could be a useful marker for identifying this phenomenon in carcinoma tissues

  3. Our results suggest that, as in the CNS, CADM1 interactions drive exocytic site assembly and promote actin network formation. These results support the broader hypothesis that the effects of cell-cell contact on beta-cell maturation and function are mediated by the same extracellular protein interactions that drive the formation of the presynaptic exocytic machinery. These interactions may be therapeutic targets for re...

  4. High expression of CADM1 on most HTLV-1-infected cells in the face of enhanced cytotoxic T lymphocyte counterselection implies that CADM1 confers a strong benefit on the virus.

  5. Decreased expression of TSLC1 is associated with the differentiation in ovarian epithelial cancer. TSLC1 might be used as a molecular marker of severity in early stage ovarian cancer, and to help differentiating benign and malignant ovarian tumors.

  6. Suppression of tumorigenesis by CADM1 may be mediated by the Rb-E2F1 (show E2F1 Antibodies) pathway.

  7. CADM1 prevents squamous cell carcinoma progression by reducing STAT3 (show STAT3 Antibodies) activity

  8. Decreased expression of TSLC1 is correlated with the malignancy of non-muscle invasive bladder cancer tissues and low TSLC1 expression may serve as a predictor for bladder cancer recurrence and progression.

  9. CADM1 deletion is associated with neuroblastoma (show ARHGEF16 Antibodies) and ganglioneuroma.

  10. Hypermethylation of CADM1 gene may be highly associated with the development of cervical cancer.

Mouse (Murine) Cell Adhesion Molecule 1 (CADM1) interaction partners

  1. The results of this study demonstrate that the synapse-organizing adhesion molecule (show NCAM1 Antibodies) SynCAM 1 has pronounced effects on neuronal connectivity in the hippocampal CA3 (show CA3 Antibodies) area.

  2. Cadm1 is a direct target of NFATc1 (show NFATC1 Antibodies), which is induced by RANKL (show TNFSF11 Antibodies) through epigenetic modification, and regulates osteoclastic bone resorption in a negative feedback manner.

  3. Data show that cell adhesion molecule 1 (SynCAM 1) generally prolongs the lifetime of spines.

  4. This experiments show that the survival rate of adult-generated neurons is increased by overexpressing SynCAM 1

  5. Our study reveals a novel mechanism of chronic NF-kappaB (show NFKB1 Antibodies) activation by CADM1 in HTLV-1 infected cells

  6. Study demonstrates that polysialic acid-SynCAM 1 defines a subpopulation of NG2 (show Vcan Antibodies) cells and identifies the presence of polysialic acid-NRP2 (show NRP2 Antibodies) in microglia

  7. CADM1 appeared to sustain gap junctional intercellular communication among alpha-cells via homophilic binding and, based on this action, CADM1 appears to prevent excessive secretion of glucagon (show GCG Antibodies) from alpha-cells.

  8. This study demonistrated that SynCAM 1 in the synaptic organization of the rod visual pathway and provide evidence for novel roles of synaptic adhesion in the structural and functional integrity of ribbon synapses.

  9. Necl-2 co-localizes with ErbB4 (show ERBB4 Antibodies) in hippocampus and and regulates ErbB4 (show ERBB4 Antibodies) signaling in cultured neurons.

  10. TGF-beta1 is a potent cytokine that provides an effective mechanism in controlling Necl-2 expression in the testis via Smad-dependent gene repression and clathrin-mediated endocytosis.

CADM1 Antigen Profile

Antigen Summary

Mediates homophilic cell-cell adhesion in a Ca(2+)- independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca(2+)-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. May act as a synaptic cell adhesion molecule that drives synapse assembly. May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.

Alternative names and synonyms associated with CADM1

  • cell adhesion molecule 1 (CADM1) antibody
  • cell adhesion molecule 1 (LOC100354915) antibody
  • immunoglobulin superfamily, member 4 (IGSF4) antibody
  • cell adhesion molecule 1 (cadm1) antibody
  • cell adhesion molecule 1 (Cadm1) antibody
  • 2900073G06Rik antibody
  • 3100001I08Rik antibody
  • AI987920 antibody
  • Bl2 antibody
  • Igsf4 antibody
  • Igsf4a antibody
  • Necl-2 antibody
  • Necl2 antibody
  • RA175 antibody
  • RA175A antibody
  • RA175B antibody
  • RA175C antibody
  • RA175N antibody
  • SgIGSF antibody
  • ST17 antibody
  • sTSLC-1 antibody
  • SynCam antibody
  • synCAM1 antibody
  • Tslc1 antibody
  • xnecl2 antibody

Protein level used designations for CADM1

immunoglobulin superfamily, member 4 , cell adhesion molecule 1 , TSLC-1 , TSLC1/Nectin-like 2/IGSF4 , immunoglobulin superfamily member 4 , immunoglobulin superfamily, member 4D variant 1 , immunoglobulin superfamily, member 4D variant 2 , nectin-like 2 , nectin-like protein 2 , spermatogenic immunoglobulin superfamily , synaptic cell adhesion molecule , truncated CADM1 protein , tumor suppressor in lung cancer 1 , NECL-2 , cell adhesion molecule 1 transcript variant 8abc , immunoglobulin superfamily member 4A , immunosuperfamily protein Bl2 , immunoglobulin superfamily, member 4A , secretory isoform of TSLC1

GENE ID SPECIES
529873 Bos taurus
100354915 Oryctolagus cuniculus
445438 Rattus norvegicus
735231 Xenopus laevis
23705 Homo sapiens
54725 Mus musculus
363058 Rattus norvegicus
479432 Canis lupus familiaris
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