Browse our CD1d Proteins (CD1D)

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CD1d Molecule Proteins (CD1D)
On are 21 CD1d Molecule (CD1D) Proteins from 8 different suppliers available. Additionally we are shipping CD1d Antibodies (203) and CD1d Kits (2) and many more products for this protein. A total of 234 CD1d products are currently listed.
AI747460, Cd1, CD1.1, CD1.2, Cd1a, Cd1d, CD1D1, Ly-38, R3
list all proteins Gene Name GeneID UniProt
CD1D 912 P15813
CD1D 12479 P11609
CD1D 25109 Q63493

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CD1d Proteins (CD1D) by Origin

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More Proteins for CD1d Interaction Partners

Cow (Bovine) CD1d Molecule (CD1D) interaction partners

  1. Data indicate that bovine CD1d is able to bind glycosphingolipids (GSLs) with fatty acid chain lengths of C18 (show BBS9 Proteins), while GSLs with fatty acids of C24 do not bind.

Rhesus Monkey CD1d Molecule (CD1D) interaction partners

  1. The expression profile of CD1d mRNA in Rhesus macaque is in accordance with the tissue distribution and the functions of NKT (show SLC22A6 Proteins) cells in other species.

Human CD1d Molecule (CD1D) interaction partners

  1. FasL (show FASL Proteins) expression in splenic CD5 (show CD5 Proteins)(+)CD1d(hi) B cells was decreased compared to the control group after TLR4 (show TLR4 Proteins) ligation.

  2. The expression of CD1d showed a significantly negative correlation with CD86 (show CD86 Proteins) level in B cells from imiquimod (IMQ)-treated mice, B6.MRLlpr mice, and lupus erythematosus (SLE) patients.

  3. CD1d-restricted peripheral T cell lymphoma in mice and humans

  4. BCR-ABL-dependent ROCK, but not TK, is involved in CD1d downregulation. We propose that ROCK, which is most likely activated by the DH/PH domain of BCR-ABL, mediates iNKT-cell immune subversion in chronic myeloid leukaemia (CML) patients by downregulating CD1d expression on CML mDCs.

  5. Importantly, among the analyzed molecules, only CD1d expression showed an association with the activation of double-negative T cells, as well as with worse ventricular function in patients with Chagas disease.

  6. Data suggest that CD1d antigen (show KY Proteins)-restricted B lymphocytes (Bc) presentation of NGcGM3 drives effective invariant natural killer T cells (iNKT) activation.

  7. the spatiotemporal distribution of CD1d molecules on the surface of antigen-presenting cells (APCs (show APCS Proteins)) modulates activation of Invariant natural killer T cells.

  8. both membrane-bound (V4) and soluble (V5) isoforms of CD1d were over-expressed in gastric tumor tissues, suggesting that they are involved in anti-tumor immune responses.

  9. This suggests that CD1D is more polymorphic than previously assumed

  10. by controlling a fundamental step in CD1d-mediated lipid antigen presentation, STAT3 (show STAT3 Proteins) signalling promotes innate immune responses driven by CD1d

Mouse (Murine) CD1d Molecule (CD1D) interaction partners

  1. The expression of CD1d showed a significantly negative correlation with CD86 (show CD86 Proteins) level in B cells from imiquimod (IMQ)-treated mice, B6.MRLlpr mice, and lupus erythematosus (SLE) patients.

  2. our data expose a previously unappreciated role for ILCs in CD1d-mediated immunity, which can modulate tissue homeostasis and inflammatory responses.

  3. CD1d-restricted peripheral T cell lymphoma in mice and humans

  4. Adipocyte CD1d plays a key role in the stimulation of adipose invariant natural killer T cells, leading to anti-inflammatory responses in high-fat diet (HFD)-fed mice.

  5. reduced development of atherosclerosis in hyperlipidaemic mice by the NKT (show CTSL1 Proteins) antagonist, without affecting NKT (show CTSL1 Proteins) cell or other lymphocyte numbers, suggests that targeting lesion inflammation via CD1d-dependent activation of NKT (show CTSL1 Proteins) cells

  6. the crystal structure of the first peptide identified to bind CD1d, p99 (show PPP1R10 Proteins), and show that it binds in the antigen-binding groove of CD1d in a manner compatible with its presentation to T cell receptors.

  7. regulatory and protective role of CD1d-dependent natural killer T cells in contact hypersensitivity, at least in part via regulation of IL-10 (show IL10 Proteins) producing B(regs)

  8. The findings support a model in which low endosomal pH controls stability and lipid raft localization of CD1d-glycolipid complexes to regulate the outcome of iNKT cell mediated responses.

  9. affects iNKT cell activation by mast cells and release of both IFN-gamma (show IFNG Proteins) and IL-13 (show IL13 Proteins)

  10. CD1d acts as a cell surface receptor that recognizes and binds oxysterols and initializes a pathway connecting oxysterol binding to PPARgamma (show PPARG Proteins) activation

CD1d (CD1D) Protein Profile

Protein Summary

This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail.

Alternative names and synonyms associated with CD1d (CD1D)

  • CD1d molecule (CD1D)
  • CD1c molecule (CD1C)
  • CD1D antigen, d polypeptide (CD1D)
  • CD1d1 antigen (Cd1d1)
  • CD1d1 molecule (Cd1d1)
  • AI747460 protein
  • Cd1 protein
  • CD1.1 protein
  • CD1.2 protein
  • Cd1a protein
  • Cd1d protein
  • CD1D1 protein
  • Ly-38 protein
  • R3 protein

Protein level used designations for CD1d Molecule Proteins (CD1D)

antigen-presenting glycoprotein CD1d , CD1-1 antigen , CD1D antigen, d polypeptide , CD1d molecule , d polypeptide , HMC class I antigen-like glycoprotein CD1D , R3G1 , T-cell surface glycoprotein CD1d , differentiation antigen CD1-alpha-3 , thymocyte antigen CD1D , T-cell surface glycoprotein CD1d1 , antigen-presenting glycoprotein CD1d1 , CD1D antigen , CD1d1 antigen

100301530 Oryctolagus cuniculus
425801 Gallus gallus
516046 Bos taurus
613268 Macaca mulatta
912 Homo sapiens
100144424 Ovis aries
469524 Pan troglodytes
12479 Mus musculus
25109 Rattus norvegicus
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