Browse our FCGRT (FCGRT) ELISA Kits

Full name:
Fc Fragment of IgG, Receptor, Transporter, alpha ELISA Kits (FCGRT)
On www.antibodies-online.com are 15 Fc Fragment of IgG, Receptor, Transporter, alpha (FCGRT) ELISA Kits from 9 different suppliers available. Additionally we are shipping FCGRT Antibodies (86) and FCGRT Proteins (24) and many more products for this protein. A total of 129 FCGRT products are currently listed.
Synonyms:
alpha-chain, FcRn
list all ELISA KIts Gene Name GeneID UniProt
FCGRT 2217 P55899
FCGRT 29558 P13599
FCGRT 14132 Q61559

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More ELISA Kits for FCGRT Interaction Partners

Human Fc Fragment of IgG, Receptor, Transporter, alpha (FCGRT) interaction partners

  1. these findings establish a novel mechanism of humoral protection in the eye involving FcRn and may facilitate vaccine and therapeutic development for other ocular surface diseases

  2. Data suggest that, unlike albumin (show ALB ELISA Kits) with low FcRn-binding affinity, albumin (show ALB ELISA Kits) with high FcRn-binding affinity (due to genetic variation/genetic engineering) is directed less to lysosomes and more to endosomes, suggestive of FcRn-directed albumin (show ALB ELISA Kits) salvage from lysosomal degradation. (FcRn = neonatal Fc receptor)

  3. the localization of FcRn alpha-chain in fixed nasal tissue, was studied.

  4. FcRn is involved in transport of aflibercept through REC (show ZDHHC2 ELISA Kits) in vitro.

  5. this study shows that FcRn may be associated with the transport and metabolism of IgG in thyrocytes and that transport is independent of IgG type, and that FcRn may be involved in Hashimoto's thyroiditis pathogenesis

  6. This review summarizes the main findings on Fc Receptor neonatal biology, function and distribution throughout different tissues.

  7. The results suggest that regardless of hyperglycemia degree, it decreases FcRn expression in placenta and blood cells and compromises the production and transfer of antibodies from maternal blood to newborns.

  8. Data indicate improved pharmacokinetics through enhanced neonatal Fc receptor (FcRn) interactions were apparent for a complementarity-determining region (CDR (show RUNX1T1 ELISA Kits)) charge-patch normalized monoclonal antibody (mAb) which was affected by non-specific clearance.

  9. analysis of binding motifs in the hFCGRT promoter that interact with their corresponding (Sp1 (show PSG1 ELISA Kits), Sp2, Sp3 (show SP3 ELISA Kits), c-Fos, c-Jun (show JUN ELISA Kits), YY1 (show YY1 ELISA Kits), and C/EBPbeta (show CEBPB ELISA Kits) or C/EBPdelta (show CEBPD ELISA Kits)) transcription factors (TFs) suggests their involvement in regulation of human FCGRT gene expression

  10. These data indicate that human FcRn facilitates the transepithelial transport of IgE in the form of IgG anti-IgE/IgE ICs.

Cow (Bovine) Fc Fragment of IgG, Receptor, Transporter, alpha (FCGRT) interaction partners

  1. The transport of IgGs in the mammary gland, by FcRn, was investigated.

  2. The present data support the notion that FcRn might be involved in the transfer of maternal immunoglobulins and in the local defense mechanism of the mammary gland.

  3. FcRn alpha chain gene has acquired several repetitive sequences in its 5'-flanking region, including multiple SINE and LINE elements. Potential binding sites for transcription factors within the 5'-flanking sequence were identified

  4. haplotype could also weaken the IgG-FcRn affinity, which may increase the IgG concentration in the milk.

Mouse (Murine) Fc Fragment of IgG, Receptor, Transporter, alpha (FCGRT) interaction partners

  1. Preproinsulin (show INS ELISA Kits) fused to Fc administered to pregnant mice efficiently accumulated in fetuses through the placental neonatal Fc receptor and protected them from subsequent diabetes development.

  2. The neonatal Fc receptor (FcRn) binds independently to both sites of the IgG homodimer with identical affinity.

  3. Characterization and screening of IgG binding to the neonatal Fc receptor.

  4. Fc receptor promotes formation of subepithelial immune complexes and subsequent glomerular pathology leading to proteinuria

  5. Abundant intracellular IgG in enterocytes and endoderm lacking FcRn.

  6. Extending serum half-life of albumin (show ALB ELISA Kits) by engineering neonatal Fc receptor (FcRn) binding.

  7. FcRn thus has a primary role within mucosal tissues in activating local immune responses that are critical for priming efficient anti-tumor immunosurveillance

  8. Neonatal Fc receptor for IgG uptake mediates intestinal absorption of IgG(1) anti-IgE/IgE immune complexes.

  9. Nck (show NCK1 ELISA Kits) and Cdc42 (show CDC42 ELISA Kits) co-operate to recruit N-WASP (show WASL ELISA Kits) to promote FcgammaR-mediated phagocytosis.

  10. AMG (show AMELX ELISA Kits) 386 clearance in FcRn-knockout mice was 18-fold faster at the 3-mg/kg dose.

FCGRT Antigen Profile

Antigen Summary

This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with FCGRT

  • Fc fragment of IgG, receptor, transporter, alpha (FCGRT) Elisa Kit
  • Fc fragment of IgG, receptor, transporter, alpha (Fcgrt) Elisa Kit
  • Fc receptor, IgG, alpha chain transporter (Fcgrt) Elisa Kit
  • alpha-chain Elisa Kit
  • FcRn Elisa Kit

Protein level used designations for FCGRT

FcRn alpha chain , IgG Fc fragment receptor transporter alpha chain , IgG receptor FcRn large subunit p51 , immunoglobulin receptor, intestinal, heavy chain , major histocompatibility complex class I-like Fc receptor , neonatal Fc receptor , neonatal Fc-receptor for Ig , IgG transcytosis and recycling receptor , MHC class I-related Fc gamma receptor , igG receptor FcRn large subunit p51 , neonatal Fc receptor FcRn , Fc receptor , Fc fragment immunoglobulin G receptor , Fc receptor, IgG, alpha chain transporter , igG Fc fragment receptor transporter alpha chain

GENE ID SPECIES
2217 Homo sapiens
476414 Canis lupus familiaris
397399 Sus scrofa
338062 Bos taurus
29558 Rattus norvegicus
14132 Mus musculus
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