Browse our HSPA1A Proteins (HSPA1A)

Full name:
Heat Shock 70kDa Protein 1A Proteins (HSPA1A)
On are 13 Heat Shock 70kDa Protein 1A (HSPA1A) Proteins from 6 different suppliers available. Additionally we are shipping HSPA1A Antibodies (158) and HSPA1A Kits (48) and many more products for this protein. A total of 230 HSPA1A products are currently listed.
hsp68, HSP70, HSP70-1, HSP70-1A, HSP70-2, Hsp70-3, hsp70-4, Hsp70.3, hsp70A1, HSP70I, Hsp72, HSPA1, HSPA1A, HSPA1B, HSPA2
list all proteins Gene Name GeneID UniProt
Rat HSPA1A HSPA1A 24472 Q07439
HSPA1A 3303 P08107
HSPA1A 193740 Q61696

Show all synonyms

HSPA1A Proteins (HSPA1A) by Origin

Select your origin of interest

Top referenced HSPA1A Proteins

  1. Human HSPA1A Protein expressed in Baculovirus infected Insect Cells - ABIN2004489 : Heck, Schöler, de Bittencourt: HSP70 expression: does it a novel fatigue signalling factor from immune system to the brain? in Cell biochemistry and function 2011 (PubMed)

More Proteins for HSPA1A Interaction Partners

Xenopus laevis Heat Shock 70kDa Protein 1A (HSPA1A) interaction partners

  1. hsp72 was more potent than hsc73 (show HSPA8 Proteins) in generating protective immune responses against the class Ia-negative 15/0 tumors.

Human Heat Shock 70kDa Protein 1A (HSPA1A) interaction partners

  1. Data suggest that both ATP- and peptide-binding domains of HSPA1A can form complexes with an AU-rich element in VEGFA (show VEGFA Proteins) mRNA in vitro; only peptide-binding domain can recover cellular VEGFA (show VEGFA Proteins) mRNA in ribonucleoprotein immunoprecipitation; RNA-binding and mRNA-stabilizing functions of HSPA1A are independent of its protein chaperone cycle. (HSPA1A = heat shock 70 kDa protein 1A; VEGFA (show VEGFA Proteins) = vascular endothelial growth factor A (show VEGFA Proteins))

  2. It has been demonstrated that HSPB8 (show HSPB8 Proteins)-BAG3 (show BAG3 Proteins)-HSP70 (show HSP70 Proteins) ensures the functionality of stress granules and restores proteostasis by targeting defective ribosomal products for degradation.

  3. The rs2763979 locus of the HSP70 (show HSP70 Proteins) genes may be associated with susceptibility to noise-induced hearing loss (NIHL) in Chinese individuals, and other HSP70 (show HSP70 Proteins) genes may also be susceptibility genes for NIHL, but the results must be further replicated in additional independent sample sets.

  4. These results suggest that NFkappaB (show NFKB1 Proteins) engaged with the kappaB motif on the promoter cooperates in Hsp70A1A activation under heat shock in human cells as part of a DNA-break repair complex including DNA-PK and PARP-1 (show PARP1 Proteins).

  5. Systematic proteomic identification of the heat shock proteins that interact with estrogen receptor alpha (show ESR1 Proteins) and biochemical characterization of the ERalpha (show ESR1 Proteins)-hsp70 (show HSP70 Proteins) interaction has been reported.

  6. epidermal Hsp70-1A contributes to the diversity of skin color by regulating the amount of melanin synthesized in melanocytes and modulating autophagic melanosome degradation in keratinocytes

  7. Extracellular Hsp72 immediately post-exercise decreased back to baseline levels by 1 h post-exercise, but cellular Hsp72 expression continued to rise and remained elevated 24 h post-exercise. These data suggest that in addition to the classic physiological biomarkers of exercise heat stress, using cellular Hsp72 as an indicator of lasting effects of stress into recovery may be most appropriate for determining long-term ef

  8. HSPA1A and HSPA8 (show HSPA8 Proteins) have roles in parturition through stimulating immune inflammatory and estrogen response

  9. Data show that BAG2 (show BAG2 Proteins) Inhibits CHIP-Mediated HSP72 ubiquitination in aged cells.

  10. The cardioprotective effect of 40-60 g/d of alcohol consumption could be due in part, to increased intracellular HSPA1A, a potent anti-inflammatory protein. Excessive intake of alcohol increases antibodies anti-Hsp60 (show HSPD1 Proteins), stimulating proinflammatory cytokines. This fact may explain the mortality from cardiovascular disease in heavy drinkers.

Cow (Bovine) Heat Shock 70kDa Protein 1A (HSPA1A) interaction partners

  1. A new SNP in the 3'-UTR of the hsp 70-1 (show HSP70 Proteins) gene in Bos taurus and Bos indicus

  2. The purified 44-kD ATPase domain from HSP70 exhibited intrinsic ATP-ADP exchange activity and acid-stable autophosphorylation at Thr204.

  3. The effect of culture conditions on expression of heat shock protein 70 (show HSP70 Proteins) and Bax (show BAX Proteins) protein in bovine blastocysts is reported.

  4. that HSC70 (show HSPA8 Proteins) preconditioning (1) attenuates the TNF-alpha (show TNF Proteins) response to endotoxin in macrophages in vitro, (2) induces cardiac functional tolerance to endotoxin and (3) reduces NF-kappaB (show NFKB1 Proteins) activity, and TNF-alpha (show TNF Proteins) and ICAM-1 (show ICAM1 Proteins) levels in heart tissue.

  5. the presence of SNPs (C/- and G/T) in the 5'-UTR region of inducible Hsp70.1 ameliorates HS response and tolerance to heat of bovine peripheral blood mononuclear cells

  6. This study showed that Hsp70 (show HSP70 Proteins) concentration is a reliable indicator of chronic stress but is not a reliable indicator of a single stressor when animals are exposed to multiple chronic stressors.

  7. Heat shock increased both HSP70 and IFNT expression in blastocysts.

  8. the promoter region of bovine hsp70.1 gene is polymorphic and may be useful in selection of dairy cows for relatively better thermotolerance and higher milk production.

  9. More DNMT1 (show DNMT1 Proteins) mRNA was detected in the transgenic somatic cell nuclear transfer (SCNT) group than the other three groups. Hsp 70.1 mRNA was detected in the in vitro fertilzation embryos. Mash2 (show ASCL2 Proteins) mRNA was present at highest levels in transgenic SCNT embryos.

  10. In Sahiwal cattle the mRNA expression of HSP70 (show HSP70 Proteins) and its protein concentration were higher (P<0.05) during peak summer (44 degrees C) and winter (10 degrees C) as compared to Frieswal cattle. This investigation supports the earlier information on the higher adaptability of indigenous cattle breeds to hot and humid conditions compared to the crossbreds of temperate cattle breeds.

Zebrafish Heat Shock 70kDa Protein 1A (HSPA1A) interaction partners

  1. Perturbation of the HSP70-HSP90 (show HSP90 Proteins) heat-shock protein axis stimulates degradation of endothelial VEGFR2 (show KDR Proteins).

  2. HSP70, the earliest induced gene in the zebrafish retina after optic nerve injury, is a crucial factor for retinal ganglion cell survival and optic nerve regeneration.

  3. HSP70 mRNA and protein were increased 2.2 fold at 0.5-24 hours after optic nerve injury then returned to control level.

  4. hsp70 is required for embryonic lens development.

  5. data suggest that HSF1 (show HSF1 Proteins) is involved in regulating constitutive lens specific expression of hsp70 in the embryonic zebrafish.

  6. in rheumatoid arthritis Significantly higher Hsp70 (heat shock protein 70 (show HSP70 Proteins)) expression was found on synovial cells than on skin fibroblasts; high co-expression of CD91 (show LRP1 Proteins) and Hsp70 on RA synovial cells

  7. These results demonstrate that induction of Hsp70 in response to heat stress is dependent on ERK (show MAPK1 Proteins) activation in Pac2 (show PSMG2 Proteins) cells.

  8. Hsp70 levels above the median were associated with a higher rate of progression to the accelerated/blast phase and a tendency toward shorter survival

Mouse (Murine) Heat Shock 70kDa Protein 1A (HSPA1A) interaction partners

  1. HSPA1A and HSPA8 (show HSPA8 Proteins) have roles in parturition through stimulating immune inflammatory and estrogen response

  2. HSPA1A/B induction is a novel approach to delay thrombus formation with minimal bleeding risk in knockout mice.

  3. HspA1A-phosphoinositide binding is complex yet specific, is mediated by both electrostatic and hydrophobic interactions, is not related to the lipid-head charge, and depends on the physicochemical properties of the lipid.

  4. The protective mechanism of HAS2 (show HAS2 Proteins) involves an increased expression of the heat-shock protein Hsp72, a chaperone with antiapoptotic activity

  5. HspA1A embeds in membranes when bound to liposomes composed of cardiolipin and sulfatide.The two domains of HspA1A differentially bind to lipids, such as cardiolipin and sulfatide.

  6. Knockdown lines were created for specific DSBs in regions of the chromosome that are coding for HSPA1A. Clonogenic cell survival was significantly lower in irradiated Hsp70 KD cells with low mHsp70 expression, than in ctrl cells.

  7. genetic manipulation of Hsp72 does not lead to alterations in metabolic processes in cardiac tissue under resting conditions, but identifies mouse strain-specific differences in cardiac lipid accumulation and insulin (show INS Proteins)-stimulated glucose clearance.

  8. Data indicate that heat shock protein 70 (Hsp70 (show HSP70 Proteins)) is higher in nuclear protein 1 (Nupr1 (show NUPR1 Proteins)+/-) haplodeficient mice, concomitant with improved insulin (show INS Proteins) sensitivity.

  9. HuR (show ELAVL1 Proteins) does not play a role in APA (show ENPEP Proteins) of the Hsp70.3 mRNA, and these two regulatory events appear to be mutually exclusive regulators of Hsp70.3 expression

  10. Activating HSP72 in rodent skeletal muscle increases mitochondrial number and oxidative capacity and decreases insulin (show INS Proteins) resistance.

Pig (Porcine) Heat Shock 70kDa Protein 1A (HSPA1A) interaction partners

  1. overexpression of the HSP70.2 (show HSPA2 Proteins) gene in multiple organs of transgenic mice improves survival during heatstroke by reducing hyperthermia, circulatory shock, and cerebral ischemia and damage

HSPA1A Protein Profile

Protein Summary

This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.

Alternative names and synonyms associated with HSPA1A

  • heat shock 70kDa protein 1A (HSPA1A)
  • heat shock 70kDa protein 1A (hspa1a)
  • heat shock 70kD protein 1A (Hspa1a)
  • heat shock cognate 70-kd protein (hsp70)
  • heat shock protein 1A (Hspa1a)
  • heat shock protein 70.2 (HSP70.2)
  • hsp68 protein
  • HSP70 protein
  • HSP70-1 protein
  • HSP70-1A protein
  • HSP70-2 protein
  • Hsp70-3 protein
  • hsp70-4 protein
  • Hsp70.3 protein
  • hsp70A1 protein
  • HSP70I protein
  • Hsp72 protein
  • HSPA1 protein
  • HSPA1A protein
  • HSPA1B protein
  • HSPA2 protein

Protein level used designations for HSPA1A

heat shock 70kDa protein 1A , HSP70-1/HSP70-2 , HSP70.1/2 , HSP70.1/HSP70.2 , heat shock 70 kDa protein 1/2 , heat shock 70 kDa protein 1A/1B , heat shock protein 70-1 , dnaK-type molecular chaperone HSP70-1 , heat shock 70kD protein 1A , heat shock-induced protein , 70 kda heat shock protein-2 , HSP70.2 , chaperone , heat shock 70 kD protein 2 , heat shock 70 kDa protein 1B , heat shock 70 kDa protein 2 , heat shock 70kDa protein 1B , heat-shock 70-kilodalton protein 1B , HSP70.1 , heat shock 70 kD protein 1 , heat shock 70 kDa protein 1 , heat shock 70 kDa protein 1A , heat-shock 70-kilodalton protein 1A , etID309743.10 , stress protein HSP70 , 68 kDa heat shock protein , heat shock 70 kDa protein 3 , heat shock protein, 70 kDa 3 , inducible heat shock protein 70

100023597 Monodelphis domestica
100554002 Anolis carolinensis
100608888 Pan troglodytes
24472 Rattus norvegicus
100381020 Xenopus laevis
3303 Homo sapiens
100354037 Oryctolagus cuniculus
282254 Bos taurus
100913152 Ovis aries
281825 Bos taurus
30671 Danio rerio
193740 Mus musculus
396648 Sus scrofa
Selected quality suppliers for HSPA1A Proteins (HSPA1A)
Did you look for something else?