Browse our MUC4 Proteins (MUC4)

On are 6 Mucin 4, Cell Surface Associated (MUC4) Proteins from 4 different suppliers available. Additionally we are shipping MUC4 Antibodies (99) and MUC4 Kits (36) and many more products for this protein. A total of 144 MUC4 products are currently listed.
4933405I11Rik, ASGP, ASGP-1, HSA276359, MUC-4, Psmc
list all proteins Gene Name GeneID UniProt
MUC4 140474  
MUC4 4585 Q99102
Rat MUC4 MUC4 303887  

MUC4 Proteins (MUC4) by Origin

More Proteins for MUC4 Interaction Partners

Mouse (Murine) Mucin 4, Cell Surface Associated (MUC4) interaction partners

  1. the role of Muc4 in driving intestinal inflammation and inflammation-associated tumorigenesis

  2. Results show that while MUC4 is highly expressed in the mouse uterus, it is not a major mucin (show SLC13A2 Proteins) in normal human endometrium. Rather, MUC4 is a potential marker of endometrial adenocarcinoma in a subset of patients.

  3. Using the Pdx1-Cre; LStopL-K-rasG12D mouse model of pancreatic carcinogenesis, in vivo early Muc4 neo-expression of in pancreatic intraepithelial neoplastic lesio (show JUN Proteins)ns ind (show MAPK1 Proteins)uced (show MAPK8 Proteins)by mutated hK- (show NFKB1 Proteins)ras is correlated with the ERK, JNK and NF-kappaB sign (show Ralb Proteins)aling p (show RACGAP1 Proteins)athways.

  4. Data show that Muc4 is upregulated and interacts with erbB2 (show ERBB2 Proteins) in gallbladders from BK5.erbB2 (show ERBB2 Proteins) mice suggesting its important role during gallbladder carcinogenesis and/or cancer growth by potentiating erbB2 (show ERBB2 Proteins) signaling.

  5. This study delineates the association and the downstream mechanisms of MUC4-regulated elevation of lipocalin-2 (show LCN2 Proteins) and its clinical significance for prognosis of pancreatic cancer.

  6. MUC4-NIDO domain significantly contributes to the MUC4-mediated metastasis of PC cells

  7. ErbB2 (show ERBB2 Proteins) and MUC4, which interact physically, activate different intracellular signalling pathways to regulate biological properties of CAPAN-2 pancreatic cancer cells

  8. As a luminal surface component, the MUC4 is situated to contribute to the non-adhesive luminal surface and to act as an intrinsic protection and survival factor for blood vessels

  9. MUC4 is regulated at the transcriptional level by CDX-1 (show CDX1 Proteins) and -2, HNF-1 alpha (show HNF1A Proteins) and -1 beta, FOXA1 (show FOXA1 Proteins)/A2, HNF-4 alpha (show HNF4A Proteins) and -4 gamma, and GATA-4 (show GATA4 Proteins), -5, and -6 factors in a cell-specific manner

  10. the expression of mucins 1 to 4 and trefoil factor 3 (show TFF3 Proteins) was down-regulated in the ileum and colon of conventional and reconventionalized mice compared with germ-free animals

Human Mucin 4, Cell Surface Associated (MUC4) interaction partners

  1. Low expression of MUC4 was associated with favorable survival, whereas high MUC4 expression did not correlate with survival in resectable pancreatic cancer patients receiving adjuvant gemcitabine treatment.

  2. the present study provides evidence that hypoxia negatively regulates MUC4 expression in PC by affecting its stability.

  3. Studies indicate that a positive or high expression level of mucin 4 (MUC4) was significantly related to poor survival in patients with resected cholangiocarcinoma (CC).

  4. MUC4beta participates in the corticosteroid resistance process, inhibiting normal GRalpha nuclear function. The high expression of MUC4 in patients with CRSwNP might participate in corticosteroid resistance.

  5. Data indicate that microRNA miR (show MLXIP Proteins)-211 can directly target the 3'UTR of mucin-4 (MUC4) and inhibit its expression at both mRNA and protein levels.

  6. The main significance of this work is the discovery of EPO (show EPO Proteins) as a novel ligand for the HER2 (show ERBB2 Proteins) receptor. Following HER2 (show ERBB2 Proteins) activation, EPO (show EPO Proteins) induces activation of FAK (show PTK2 Proteins) and subsequent activation of beta1-integrin, via inside-out signaling. This complex results in downstream activation of ERK1/2 and a sustained up regulation of both MUC4 and the HER2 (show ERBB2 Proteins) receptor

  7. MUC4 promotes the migration and proliferation of BxPC-3 cells.

  8. The prognostic accuracy of TNM (show ODZ1 Proteins) stage, UCLA Integrated Scoring System (UISS), and Mayo clinic stage, size, grade, and necrosis score (SSIGN) prognostic models was improved when MUC4 expression was added.

  9. High MUC4 expression is associated with colorectal cancer cell migration and invasion.

  10. authors show for the first time that beta-catenin (show CTNNB1 Proteins) directly governs MUC4 in pancreatic cancer.

Pig (Porcine) Mucin 4, Cell Surface Associated (MUC4) interaction partners

  1. Polymorphism of FUT1 (show FUT1 Proteins) and MUC4 associated with resistance to colibacteriosis was determined.

  2. Haplotype phylogeny analyses indicated that MUC4 had evolved divergently in Chinese and Western pigs.

  3. A SNP in exon 7 of the mucin 4 (MUC4) gene (DQ848681:g.8227C>G), shown to be in close linkage disequilibrium with the F4bcR locus, has been used as marker to identify ETEC susceptible pigs.

  4. data suggest that MUC4 could play an important role in the establishment of an optimal uterine environment that would increase embryonic survival during pig gestation

MUC4 Protein Profile

Protein Summary

The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. At least two dozen transcript variants of this gene have been found, although for many of them the full-length transcript has not been determined or they are found only in tumor tissues. This gene contains a region in the coding sequence which has a variable number (>100) of 48 nt tandem repeats.

Alternative names and synonyms associated with MUC4

  • mucin 4 (Muc4)
  • mucin 4 (LOC100350577)
  • mucin 4, cell surface associated (MUC4)
  • mucin 4, cell surface associated (Muc4)
  • 4933405I11Rik protein
  • ASGP protein
  • ASGP-1 protein
  • HSA276359 protein
  • MUC-4 protein
  • Psmc protein

Protein level used designations for MUC4

ascites sialoglycoprotein , mucin 4, ASGP , mucin-4 , pancreatic adenocarcinoma mucin , testis mucin , mucin 4, tracheobronchial , tracheobronchial mucin , ASGP , MUC-4 , pre-sialomucin complex , sialomucin ascites sialoglycoprotein-1 , sialomucin complex

140474 Mus musculus
100350577 Oryctolagus cuniculus
4585 Homo sapiens
303887 Rattus norvegicus
100157344 Sus scrofa
786701 Bos taurus
100724323 Cavia porcellus
488024 Canis lupus familiaris
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