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Browse our XCL1 Proteins (XCL1)

Full name:
Chemokine (C Motif) Ligand 1 Proteins (XCL1)
On are 46 Chemokine (C Motif) Ligand 1 (XCL1) Proteins from 15 different suppliers available. Additionally we are shipping XCL1 Antibodies (107) and XCL1 Kits (39) and many more products for this protein. A total of 200 XCL1 products are currently listed.
AI661682, ATAC, LOC100227529, LPTN, Ltn, SCM-1, SCM-1a, SCM1, SCM1A, SCYC1, XCL1
list all proteins Gene Name GeneID UniProt
XCL1 16963 P47993
XCL1 171371 P51672
XCL1 6375 P47992

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XCL1 Proteins (XCL1) by Origin

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Top referenced XCL1 Proteins

  1. Human XCL1 Protein expressed in Escherichia coli (E. coli) - ABIN667105 : Yoshida, Imai, Takagi, Nishimura, Ishikawa, Yaoi, Yoshie: Structure and expression of two highly related genes encoding SCM-1/human lymphotactin. in FEBS letters 1996 (PubMed)
    Show all 2 references for ABIN667105

  2. Mouse (Murine) XCL1 Protein expressed in Baculovirus infected Insect Cells - ABIN2008149 : Beck: Visualizing neural networks. in Methods (San Diego, Calif.) 2003 (PubMed)
    Show all 2 references for ABIN2008149

  3. Human XCL1 Protein expressed in Baculovirus infected Insect Cells - ABIN2003198 : Zavala-Flores, Villatoro-Hernandez, Gamez-Escobedo, Franco-Molina, Rangel-Colmenero, Villanueva-Olivo, Gutierrez-Puente, de Oca-Luna, Valdés-Flores, Saucedo-Cardenas: Production of biologically active human lymphotactin (XCL1) by Lactococcus lactis. in Biotechnology letters 2008 (PubMed)
    Show all 2 references for ABIN2003198

More Proteins for XCL1 Interaction Partners

Mouse (Murine) Chemokine (C Motif) Ligand 1 (XCL1) interaction partners

  1. Data show that mice lacking either XCL1 or XCR1 (show XCR1 Proteins) exhibit similar specific defects in intestinal T cell populations as XCR1 (show XCR1 Proteins)-dendritic cells (DC)-deficient mice. Therefore it is possible that the XCR1 (show XCR1 Proteins)-XCL1 axis itself is directly involved in intestinal T cell homeostasis, via a mechanism that might either involve interaction with XCR1 (show XCR1 Proteins)+ DCs or be independent of this pathway.

  2. T inflammatory memory CD8 (show CD8A Proteins) T cells participate to antiviral response and generate secondary memory cells with an advantage in XCL1 production

  3. XCL1-mediated accumulation of dendritic cells in the thymic medulla contributes to naturally occurring regulatory T cell development and is regulated by Aire (show AIRE Proteins).

  4. Data report the identification of a new stable molecular assembly formed between the ATAC and Mediator complexes in mouse embryonic stem cells.

  5. The expression patterns of XCR1 (show XCR1 Proteins) and XCL1 were conserved in human and mice blood cells, including certain dendritic cell subsets.

  6. MIP-1alpha (show CCL3 Proteins), MIP-1beta (show CCL4 Proteins), RANTES (show CCL5 Proteins), and ATAC/lymphotactin function together with IFN-gamma (show IFNG Proteins) as type 1 cytokines.

  7. Adenovirus-mediated intratumoral Lptn gene transfer potentiates the antibody-targeted superantigen therapy of experimental melanoma.

  8. In a brain-targeted HIV-1 Tat transgenic model, Tat exp (show TAT Proteins)ression up-regulates XCL1 production not only in Tat-expressing murine astrocytes, but also in monocytes and macrophages/microglia.

  9. Lymphotactin gene-modified dendritoma induces T-cell proliferation and strong cytotoxic T lymphocytes reaction against allogenic hepatocellular carcinoma cells.

  10. Results describe the role of XCL1 during the course of the immune response to pulmonary M. tuberculosis infection.

Human Chemokine (C Motif) Ligand 1 (XCL1) interaction partners

  1. This study defines a Glycosaminoglycan binding surface on XCL1 dimer that includes residues that are important for HIV-1 inhibition.

  2. Electrostatics and Hydrophobic Effects in the Metamorphic Protein Human Lymphotactin

  3. XCL1 acts via direct interaction with the external viral envelope glycoprotein (show ERVW-1 Proteins), gp120 (show ITIH4 Proteins), to block HIV-1 infection

  4. analysis of XCL1 and XCL2 (show XCL2 Proteins), members of the C-chemokine (show CCL1 Proteins) subfamily, in the immune system

  5. identified 13 ADCC-activated genes. Six gene expression assays including 8 of the 13 genes (CCL3 (show CCL3 Proteins), CCL4/CCL4L1 (show CCL4 Proteins)/CCL4L2, CD160 (show CD160 Proteins), IFNG (show IFNG Proteins), NR4A3 (show NR4A3 Proteins) and XCL1/XCL2 (show XCL2 Proteins)) were analyzed in 127 kidney biopsies

  6. XCL1 displays antimicrobial activity against E. coli and S. aureus.

  7. XCL1-mediated inhibition is associated with direct interaction of the chemokine (show CCL1 Proteins) with the HIV-1 envelope.

  8. In native annulus fibrosus tissue homeostasis and repair, CXCR3 (show CXCR3 Proteins) is evident, whereas XCL1 could not be detected.

  9. The expression patterns of XCR1 (show XCR1 Proteins) and XCL1 were conserved in human and mice blood cells, including certain dendritic cell subsets.

  10. Data indicated increased expression of XCL1 in CD4 (show CD4 Proteins)+ and CD8 (show CD8A Proteins)+ T cells in Wegener's granulomatosis (WG), and suggest that XCL1 might be a key modulator of T cell recruitment in WG.

XCL1 Protein Profile

Protein Summary

This gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1.

Alternative names and synonyms associated with XCL1

  • chemokine (C motif) ligand 2 (XCL2)
  • lymphotactin (LOC100227529)
  • chemokine (C motif) ligand 1 (Xcl1)
  • chemokine (C motif) ligand 1 (XCL1)
  • Interferon-gamma level (IFNG)
  • lymphotactin-like (LOC100349255)
  • AI661682 protein
  • ATAC protein
  • LOC100227529 protein
  • LPTN protein
  • Ltn protein
  • SCM-1 protein
  • SCM-1a protein
  • SCM1 protein
  • SCM1A protein
  • SCYC1 protein
  • XCL1 protein

Protein level used designations for XCL1

chemokine (C motif) ligand 1 , lymphotactin , c motif chemokine 1 , cytokine SCM-1 , lymphotaxin , small inducible cytokine subfamily C, member 1 (lymphotactin) , small-inducible cytokine C1 , SCM-1-alpha , XC chemokine ligand 1 , single cysteine motif 1a

735318 Pan troglodytes
100227529 Taeniopygia guttata
16963 Mus musculus
171371 Rattus norvegicus
6375 Homo sapiens
100714756 Cavia porcellus
100153155 Sus scrofa
319096 Bos taurus
443448 Ovis aries
395914 Gallus gallus
100349255 Oryctolagus cuniculus
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