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The expression of ApoA-I (show APOA1 Proteins) and ApoA-II mRNA in the reproductive tract and their antibacterial properties against Escherichia coli suggest that seminal apolipoproteins play an important role in innate immunity in the rainbow trout reproductive tract.
ApoAII-ATQ (show ALDH7A1 Proteins)/AT not only distinguished the early stages of pancreatic cancer from healthy controls but also identified patients at high risk for pancreatic malignancy.
ApoA1 (show APOA1 Proteins) and ApoA2 were independently associated with cognitive impairment.
Plasma apoB (show APOB Proteins) pool size of VLDL containing apoA-II is much smaller than that of VLDL without apoA-II, and this was caused by a very low rate of secretion of this VLDL type into plasma.
Clematichinenoside prevented dyslipidemia-induced atherosclerosis via hepatic PPARalpha (show PPARA Proteins)/APOA1 (show APOA1 Proteins)/APOA2/APOC3 (show APOC3 Proteins) metabolism.
APOA-II polymorphism and oxidative stress is associated with poor prognosis in patients with type 2 diabetes.
Apolipoprotein AII was detected as a protein associated with the urinary protein/urinary creatinine levels in pediatric idiopathic steroid-sensitive nephrotic syndrome
Apolipoprotein A-II/B significantly improves risk prediction of overall survival, also in carotid surgery patients with lower LDL levels
Apolipoprotein A-II and the regulation of high density lipoproteins in cardiovascular disease. [Review]
influence of apolipoprotein A-I (show APOA1 Proteins) and apolipoprotein A-II availability on nascent HDL (show HSD11B1 Proteins) heterogeneity
We have cloned the cDNA encoding human ApoA-II and achieved its high-level secreting expression with a yield of 65 mg/L of yeast culture
In vivo, neither C57 nor FVB apoA-II protein levels are affected by the absence of apoE (show APOE Proteins), while an apoE (show APOE Proteins)/apoA-I (show APOA1 Proteins) double deficiency results in a 50% decrease of plasma FVB apoA-II but results in undetectable levels of C57 apoA-II in the plasma.
ApoA-I (show APOA1 Proteins) deficiency in mice is associated with redistribution of apoA-II and aggravated AApoAII amyloidosis.
Exacerbated hepatitis is observed in ApoA-II-deficient mice, indicating that ApoA-II plays a suppressive role in concanavalin A-induced hepatitis under physiological conditions.
Apoa2 injected into mice induced amyloidosis.
the presence of apoA-II on HDL (show HSD11B1 Proteins) particles inhibits the ability of endothelial lipase (show LIPG Proteins) to influence the metabolism of HDL (show HSD11B1 Proteins) in vivo
These studies indicate that increased levels of APOA2 protein lead to earlier and greater amyloid deposition and enhanced sensitivity to the transmission of amyloid fibrils in transgenic mice.
ApoAII is efficiently reabsorbed in kidney proximal tubules in relation to its plasma concentration
apoAII regulates the metabolism of triglyceride-rich lipoproteins, with HDL (show HSD11B1 Proteins) serving as a plasma reservoir of apoAII that is transferred to the triglyceride-rich lipoproteins in the same way as VLDL and chylomicrons acquire most of their apoCs from HDL (show HSD11B1 Proteins)
To understand the mechanism of amyloid fibril formation by apoA-II, we examined the polymerization of synthetic partial peptides of apoA-II in vitro.
The bovine APOA2 gene may be a strong candidate gene for body traits in the cattle breeding program.
The APOA2:c.131T>A polymorphism was associated with the fatty acid composition of backfat.
This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia.
, apolipoprotein A2
, antimicrobial peptide BAMP-1