Browse our MORF4L2 Proteins (MORF4L2)

Full name:
Mortality Factor 4 Like 2 Proteins (MORF4L2)
On are 19 Mortality Factor 4 Like 2 (MORF4L2) Proteins from 7 different suppliers available. Additionally we are shipping MORF4L2 Antibodies (44) and many more products for this protein. A total of 68 MORF4L2 products are currently listed.
2410017O14Rik, DKFZp468A0820, LRRG00119, mKIAA0026, MORF4L2, MORFL2, Mrgx, Sid393p
list all proteins Gene Name GeneID UniProt
MORF4L2 9643 Q15014
MORF4L2 56397 Q9R0Q4
MORF4L2 317413 Q6QI89

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MORF4L2 Proteins (MORF4L2) by Origin

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Top referenced MORF4L2 Proteins

  1. Human MORF4L2 Protein expressed in Escherichia coli (E. coli) - ABIN667402 : Tominaga, Leung, Rookard, Echigo, Smith, Pereira-Smith: MRGX is a novel transcriptional regulator that exhibits activation or repression of the B-myb promoter in a cell type-dependent manner. in The Journal of biological chemistry 2003 (PubMed)
    Show all 2 references for 667402

More Proteins for MORF4L2 Interaction Partners

Human Mortality Factor 4 Like 2 (MORF4L2) interaction partners

  1. Suberoylanilide hydroxamic acid enhanced the expression of malignant genes such as MORF4L2 in lung cancer cells remaining after treatment, creating a more drug-resistant state.

  2. can repress or activate the B-myb (show MYBL2 Proteins) promoter depending on the cell type studied, suggesting that there may be tissue-specific functions of this protein

  3. The transcriptional status of four key genes, thymidylate synthase (TYMS (show TYMS Proteins)), MORF-related gene X (MRGX), Bcl2 (show BCL2 Proteins)-antagonist/killer (BAK (show BAK1 Proteins)), and ATPase, Cu(2+) transporting beta polypeptide (show MS4A2 Proteins) (ATP7B (show ATP7B Proteins)), can accurately predict response to 5-FU.

Mouse (Murine) Mortality Factor 4 Like 2 (MORF4L2) interaction partners

  1. Data show that MRGX is ubiquitously expressed in all tissues of adult mice and also during embryogenesis, and overlaps with its homolog Mrg15 (show MORF4L1 Proteins).

MORF4L2 Protein Profile

Protein Summary

Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones (By similarity).

Alternative names and synonyms associated with MORF4L2

  • mortality factor 4 like 2 (morf4l2)
  • mortality factor 4 like 2 (MORF4L2)
  • similar to Mortality factor 4-like protein 2 (MORF-related gene X protein) (Transcription factor-like protein MRGX) (MSL3-2 protein) (MORF4L2)
  • mortality factor 4 like 2 (Morf4l2)
  • 2410017O14Rik protein
  • DKFZp468A0820 protein
  • LRRG00119 protein
  • mKIAA0026 protein
  • MORF4L2 protein
  • MORFL2 protein
  • Mrgx protein
  • Sid393p protein

Protein level used designations for MORF4L2

mortality factor 4 like 2 , Mortality factor 4-like protein 2 , MORF-related gene X protein , MSL3-2 protein , mortality factor 4-like protein 2 , protein MSL3-2 , transcription factor-like protein MRGX , sid 393 , transcription factor-like protein Mrgx , liver regeneration-related protein LRRG00119 , MORF-related gene X

496573 Xenopus (Silurana) tropicalis
100174394 Pongo abelii
697637 Macaca mulatta
481001 Canis lupus familiaris
9643 Homo sapiens
538442 Bos taurus
56397 Mus musculus
317413 Rattus norvegicus
465783 Pan troglodytes
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