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Browse our MYF5 Proteins (MYF5)

Full name:
Myogenic Factor 5 Proteins (MYF5)
On are 6 Myogenic Factor 5 (MYF5) Proteins from 3 different suppliers available. Additionally we are shipping MYF5 Antibodies (112) and MYF5 Kits (9) and many more products for this protein. A total of 136 MYF5 products are currently listed.
B130010J22Rik, bHLHc2, cb641, Myf-5, MYF5, xmyf-5, Xmyf5, zgc:110509
list all proteins Gene Name GeneID UniProt
MYF5 4617 P13349
MYF5 17877 P24699
Rat MYF5 MYF5 299766  

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MYF5 Proteins (MYF5) by Origin

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More Proteins for MYF5 Interaction Partners

Zebrafish Myogenic Factor 5 (MYF5) interaction partners

  1. Loss of Myf5 function results in a cascade effect that begins with abnormal formation of the dorsal organizer during gastrulation, causing defects in myf5-knockdown embryos

  2. the secreted ligand Dkk3a binds to the membrane receptor Itgalpha6b, which increases the protein level of phosphorylated p38a (show MAPK14 Proteins) and activates myf5 promoter activity of zebrafish embryos during myogenesis.

  3. a novel intronic microRNA, miR (show MYLIP Proteins)-In300, which is derived from I300 of the first intron of zebrafish myf5, enables significant repression of myf5 promoter activity through silencing the long isoform of the Dickkopfs-3 gene.

  4. A novel regulatory base sequence functions as a key element to drive the somite-specificity of myf-5.

  5. Functional analysis of intron 1 showed a strong, negative, cis (show CISH Proteins)-regulatory element located at +502/+835, and this is the first study to identify a novel, cis (show CISH Proteins)-acting silencer that is crucial to negatively regulating myf-5 expression.

  6. Foxd3 (show FOXD3 Proteins), a well-known regulator in neural crest development, is also involved in myf5 regulation

  7. Myf5 and Myod (show MYOD1 Proteins) function independently during cranial myogenesis.

  8. cell lineage-specific expression of myf5 is delicately orchestrated by multiple modules within the distal upstream region. This study provides an insight to understand the molecular control of myf5 and myogenesis in the zebrafish.

Human Myogenic Factor 5 (MYF5) interaction partners

  1. Pitx2c (show PITX2 Proteins) expression is reactivated, while expression of Myf5 is downregulated in human systolic heart failure as determined by qRT-PCR and Western blot analyses.

  2. results are the first demonstration of a myogenic conversion of human mesenchymal and endothelial cells by Myf5

  3. DUX4c induces the MYF5 protein and myoblast proliferation, and has a role in facioscapulohumeral muscular dystrophy

  4. The myogenic basic helix-loop-helix family of transcription factors, MyoD (show MYOD1 Proteins), Myf5, myogenin (show MYOG Proteins), and MRF4 (show MYF6 Proteins), can each activate the muscle differentiation program.

  5. Mrf4 (show MYF6 Proteins) expression precedes or is contemporaneous with that of Myf5, suggesting that this transcription factor plays a hitherto unsuspected role in myogenesis

  6. Myogenin (show MYOG Proteins) and myogenic differentiation factor D (MyoD (show MYOD1 Proteins)) mRNAs increased (P < 0.05) in young and old, whereas myogenic factor (show MYOG Proteins) (myf)-5 mRNA increased in young only (P < 0.05). Myf-6 (show MYF6 Proteins) protein increased (P < 0.05) in both young and old.

  7. A novel homozygous polymorphism that prevented the binding of MYF-5 to FOXE1 (show FOXE1 Proteins) promoter and affected the FOXE1 (show FOXE1 Proteins) expression was found in 45% nonsyndromic cleft palate.

Cow (Bovine) Myogenic Factor 5 (MYF5) interaction partners

  1. The effects of myostatin (show MSTN Proteins) and myogenic factor 5 polymorphisms on growth and muscle traits of Marchigiana breed were assessed.

  2. Bos taurus MYF5 activates MYF5 and MYOD1 (show MYOD1 Proteins) expression in cultured fibroblasts.

  3. A polymorphism showed an influence on Myf5 gene expression in the longissimus dorsi muscle

  4. results suggest that MyoD and Myf5 influence the MyHC isoform expression, although the effects are not decisive in specifying the phenotypes of adult muscles

Mouse (Murine) Myogenic Factor 5 (MYF5) interaction partners

  1. Novel RNA-binding activity of MYF5 enhances Ccnd1 (show CCND1 Proteins) mRNA translation during myogenesis.

  2. Transcription of the skeletal muscle program is achieved by the expression of MyoD (show MYOD1 Proteins), which binds to the same sites as Myf5, indicating that each factor regulates distinct steps in gene initiation and transcription at a shared set of binding sites

  3. The Myf5- and Myogenin (show MYOG Proteins)-deficient mice showed a partial or complete, respectively, loss of TMC (show STT3A Proteins) in an otherwise regularly structured thymus.

  4. Elimination of Myf5(Cre)-DTA cells on a Myod (show MYOD1 Proteins) null background did not result in the total absence of skeletal muscles

  5. A muscle-specific (show EIF3K Proteins) regulatory element of p57(kip2 (show CDKN1C Proteins)) directly activated by muscle regulatory factors in myoblasts but repressed by the Notch (show NOTCH1 Proteins) targets Hes1/Hey1 (show HEY1 Proteins) in progenitor cells, is identified.

  6. lineage tracing based on multiple reporter lines has demonstrated that regardless of common ancestral expression of Myf5, there is a clear distinction between periocular myogenic and non-myogenic cell lineages

  7. The results demonstrate the heterogeneity and functional differences of the Myf5- and non-Myf5-lineage cells in the white adipose tissue.

  8. Adult satellite cells derive from progenitors that first express the myogenic determination gene Myf5 during fetal stages of myogenesis.

  9. Direct molecular regulation of the myogenic determination gene Myf5 by Pax3 (show PAX3 Proteins), with modulation by Six1 (show SIX1 Proteins)/4 factors, is exemplified by the -111 kb-Myf5 enhancer

  10. The observations provide a mechanism linking Myf5 levels to muscle stem cell heterogeneity and fate by exposing two distinct and opposing phenotypes associated with Myf5 haploinsufficiency.

Xenopus laevis Myogenic Factor 5 (MYF5) interaction partners

  1. myf5 upregulation can be a good criterion for the activation of adult myogenesis during X. laevis metamorphosis

  2. During early Xenopus development Myf5 protein regulates a distinct myogenic program.

  3. FGF8 (show FGF8 Proteins), Wnt8 (show WNT8A Proteins) and Myf5 are target genes of Tbx6 (show TBX6 Proteins) during anteroposterior specification in Xenopus embryo

MYF5 Protein Profile

Protein Summary

Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein.

Alternative names and synonyms associated with MYF5

  • myogenic factor 5 (myf5)
  • myogenic factor 5 (MYF5)
  • myogenic factor 5 (Myf5)
  • B130010J22Rik protein
  • bHLHc2 protein
  • cb641 protein
  • Myf-5 protein
  • MYF5 protein
  • xmyf-5 protein
  • Xmyf5 protein
  • zgc:110509 protein

Protein level used designations for Myogenic Factor 5 Proteins (MYF5)

myogenic regulatory factor 5 , myogenic factor 5 , MyoD family , myogenic factor-5 , basic helix-loop-helix nuclear protein , class C basic helix-loop-helix protein 2 , myf-5 , Myf5 homolog , myogenic regulatory factor MYF-5 , myogenic factor Xmyf-5

58097 Danio rerio
394529 Xenopus (Silurana) tropicalis
443159 Ovis aries
467081 Pan troglodytes
482582 Canis lupus familiaris
697426 Macaca mulatta
100013522 Monodelphis domestica
4617 Homo sapiens
395633 Gallus gallus
407603 Sus scrofa
281335 Bos taurus
17877 Mus musculus
299766 Rattus norvegicus
397960 Xenopus laevis
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