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Polymorphisms of CRHR1 (show CRHR1 ELISA Kits) and AVPR1b may modify susceptibility to mood disorders.
The results suggest that the AVPR1B gene rs28373064 is linked to emotional empathy and prosociality.
AA genotype of rs28418396 single-nucleotide polymorphism near the arginine vasopressin receptor 1b gene is associated with serious adverse events in patients with septic shock treated with vasopressin (show AVP ELISA Kits) and norepinephrine.
Genetic variance of arginine vasopressin receptor 1B(AVPR1B) contributes to overweight and data indicate a link between AVPR1B variance and diabetes mellitus development
The association of AVPR1B G*A-haplotype (rs28632197 and rs33911258, respectively) and decreased Self-transcendence (TCI (show LXN ELISA Kits)-125) was demonstrated in the total sample and in Udmurts.
Participants carrying both GG/GA variant of AVPR1b rs28373064 and AA variant of clock rs6832769 showed highest scores on the Emotional prosocial tendency measure. the clock gene and OXT (show OXT ELISA Kits)/AVP (show AVP ELISA Kits) systems are intertwined and contribute to human prosociality.
The associations of the AVP (show AVP ELISA Kits) 1B receptor may be specific to reactive, emotional rather than proactive or callous types of aggression.
association between polymorphisms of AVPR1b gene and psychotic dimension.possible involvement of the AVPR1b gene in the etiology of psychotic features in the course of affective disorders
AVPR1B genetic variation has a role in suicide attempt etiology characterized by elevated depression levels.
The results of thi study showed that no association was found for alleles, genotypes, or haplotype analysis for AVPR1b genes and melancholic depression.
Data identify specific brain areas that may be a part of a neural circuit that includes Avpr1b-expressing cells in the CA2 (show CA2 ELISA Kits) region of the hippocampus. It is thought that this circuit, when working properly, plays a role in how an animal evaluates its social context.
Data show that cryptochrome Cry1 (show CRY1 ELISA Kits) and Cry2 (show CRY2 ELISA Kits) expression must be circadian and appropriately phased to support rhythms, and arginine vasopressin (AVP (show AVP ELISA Kits)) receptor signaling is required to impose circuit-level circadian function.
The data of this study indicate that the hippocampal CA2 (show CA2 ELISA Kits) is important for attacking in response to a male intruder and that the Avpr1b, likely through its role in regulating CA2 (show CA2 ELISA Kits) synaptic plasticity, is a necessary mediator
this study found that circadian rhythms of behavior (locomotor activity), clock gene expression, and body temperature immediately reentrained to phase-shifted light-dark cycles in mice lacking vasopressin receptors V1a and V1b (V1a(-/-)V1b(-/-)).
vasopressin V1b receptor is involved in the mediation of anxious behavior of animals but is not involved in the mechanism underlying the influence of negative psychoemotional state on Lewis lung carcinoma metastasis
distribution and functional studies of the Avpr1b have established its major role in the pituitary where it plays a pivotal part in the regulation of the HPA (show HPSE ELISA Kits) response to stress, and in particular to acute stress[review]
These findings suggest that while Avpr1b -/- mice may be able to form dominance hierarchies they appear to employ alternate strategies.
Overexpression of the V3 vasopressin (show AVP ELISA Kits) receptor in transgenic mice corticotropes leads to increased basal corticosterone.
mice without the V1bR exhibit markedly reduced aggression and modestly impaired social recognition.
the V1b receptor plays a crucial role in regulating hypothalamic-pituitary-adrenal axis activity
The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known.
pituitary vasotocin receptor
, vasopressin V1b receptor
, arginine vasopressin receptor 1B
, vasopressin V1b receptor-like
, AVPR V1b
, AVPR V3
, antidiuretic hormone receptor 1B
, arginine vasopressin receptor 3
, pituitary vasopressin receptor 3
, vasopressin V3 receptor
, V3/V1b pituitary vasopressin receptor
, antidiuretic hormone receptor 1b
, arginine vasopressin type 1b receptor
, AVP receptor V3