Browse our Sepiapterin Reductase Proteins (SPR)

On are 18 Sepiapterin Reductase (SPR) Proteins from 8 different suppliers available. Additionally we are shipping Sepiapterin Reductase Antibodies (99) and Sepiapterin Reductase Kits (9) and many more products for this protein. A total of 135 Sepiapterin Reductase products are currently listed.
AA409688, CG12117, DDBDRAFT_0188686, DDBDRAFT_0191275, DDB_0188686, DDB_0191275, Dmel\\CG12117, ENSMUSG00000071345, Gm10328, NK1R, NKIR, SDR38C1, SPR, sptr, SR, Tac1r, xspr
list all proteins Gene Name GeneID UniProt
SPR 20751  
SPR 29270 P18297
SPR 6697 P35270

Sepiapterin Reductase Proteins (SPR) by Origin

More Proteins for Sepiapterin Reductase Interaction Partners

Mouse (Murine) Sepiapterin Reductase (SPR) interaction partners

  1. SPR-mediated reduction of sepiapterin and redox cycling occur by distinct mechanisms

  2. biopterin contents in the brains of these knock-out mice were moderately decreased from postnatal day 0 (P0) and remained constant up to P21

  3. These data suggest an essential role of SPR in the biosynthesis of BH4, and that the SPR gene could be a candidate gene for PARK3.

Human Sepiapterin Reductase (SPR) interaction partners

  1. Expression substance P/neurokinin A (show TAC1 Proteins)/hemokinin-1 and their preferred neurokinin 1/neurokinin 2 (show TAC1 Proteins) receptors are dysregulated in uterine leiomyomata.

  2. results suggest that ARRB1 (show ARRB1 Proteins) plays an essential role in NK1R (show TACR1 Proteins)-mediated cell proliferation and G2/M transition in glioblastoma cells. Interference with ARRB1 (show ARRB1 Proteins)-mediated signaling via NK1R (show TACR1 Proteins) may have potential significance for therapeutic strategies targeting glioblastoma.

  3. The allele frequencies for the SPR c.596-2A > G (0.7%) polymorphism is not a major cause of Parkinson's disease in the Maltese.

  4. Data suggest that endogenous tachykinin ligands for neurokinin-1 receptor exhibit large variations in binding/activation kinetics; substance P (show TAC1 Proteins) exhibits fast association kinetics; neurokinin A (show TAC1 Proteins) exhibits slow association kinetics.

  5. We showed that pretreating a cardiomyocyte cell line (H9C2) and a TNBC cell line (MDA-MB 231) with aprepitant, a SP receptor antagonist that is routinely used to treat chemotherapy-associated nausea, decreased DOX-induced reduction of viability, apoptotic cell death, and ROS (show ROS1 Proteins) production in cardiomyocytes

  6. These findings reveal important insight into the molecular mechanisms of the NK1R (show TACR1 Proteins) complex as a critical component in a model of pediatric liver cancer and may support the development of novel therapeutic interventions for hepatoblastoma

  7. Neuropeptide signaling through neurokinin-1 (show TAC1 Proteins) and neurokinin-2 (show TAC1 Proteins) receptors augments antigen presentation by human dendritic cells

  8. Inhibition of CaV2.3 (show CACNA1E Proteins) channels by NK1 (show CD160 Proteins) receptors is sensitive to membrane cholesterol but insensitive to caveolin-1 (show CAV1 Proteins).

  9. We earlier presented evidence for a physical interaction between ODC (show ODC1 Proteins) and SPR and we showed that RNAi-mediated knockdown of SPR expression significantly reduced native ODC (show ODC1 Proteins) enzyme activity and impeded Neuroblastoma (show ARHGEF16 Proteins) cell proliferation.

  10. NK-1 (show CD160 Proteins) activation could enhance EGFR (show EGFR Proteins) expression and phosphorylation, and then activate EGFR (show EGFR Proteins) related Erk/MAPK (show MAPK1 Proteins) and Akt (show AKT1 Proteins) pathway.

Cow (Bovine) Sepiapterin Reductase (SPR) interaction partners

  1. this study demonstrates an important role of endothelial SPR in modulating tetrahydrobiopterin and nitric oxide bioavailability

Sepiapterin Reductase (SPR) Protein Profile

Protein Summary

This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P.

Alternative names and synonyms associated with Sepiapterin Reductase (SPR)

  • Sepiapterin reductase (Sptr)
  • sepiapterin reductase (sprE)
  • sepiapterin reductase (CpipJ_CPIJ000511)
  • sepiapterin reductase (sr)
  • sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) (spr)
  • Sepiapterin reductase (spre)
  • sepiapterin reductase (Spr)
  • sepiapterin reductase (spre)
  • sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) (Spr)
  • sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) (SPR)
  • tachykinin receptor 1 (TACR1)
  • tachykinin receptor 1 (Tacr1)
  • AA409688 protein
  • CG12117 protein
  • DDBDRAFT_0188686 protein
  • DDBDRAFT_0191275 protein
  • DDB_0188686 protein
  • DDB_0191275 protein
  • Dmel\\CG12117 protein
  • ENSMUSG00000071345 protein
  • Gm10328 protein
  • NK1R protein
  • NKIR protein
  • SDR38C1 protein
  • SPR protein
  • sptr protein
  • SR protein
  • Tac1r protein
  • xspr protein

Protein level used designations for Sepiapterin Reductase Proteins (SPR)

sepiapterin reductase , CG12117-PA , Sptr-PA , Sepiapterin reductase , short chain dehydrogenase/reductase family 38C, member 1 , 7,8-dihydrobiopterin:NADP+ oxidoreductase , NK-1 receptor , NK-1R , substance-P receptor , tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor) , SPR , neurokinin 1 receptor , substance p receptor

31781 Drosophila melanogaster
1793292 Rhodopirellula baltica SH 1
6031370 Culex quinquefasciatus
8627440 Dictyostelium discoideum AX4
100145068 Xenopus (Silurana) tropicalis
100195245 Salmo salar
100379197 Bombyx mori
100528817 Ictalurus punctatus
20751 Mus musculus
29270 Rattus norvegicus
6697 Homo sapiens
533836 Bos taurus
380273 Xenopus laevis
6869 Homo sapiens
24807 Rattus norvegicus
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