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Browse our FAK (PTK2) ELISA Kits

Full name:
PTK2 Protein tyrosine Kinase 2 ELISA Kits (PTK2)
On www.antibodies-online.com are 29 PTK2 Protein tyrosine Kinase 2 (PTK2) ELISA Kits from 8 different suppliers available. Additionally we are shipping FAK Antibodies (689) and FAK Proteins (15) and many more products for this protein. A total of 757 FAK products are currently listed.
Synonyms:
Fadk, FAK, FAK1, FRNK, mKIAA4203, p125FAK, pp125FAK, PPP1R71

FAK (PTK2) ELISA Kits by Reactivity

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More ELISA Kits for FAK Interaction Partners

Human PTK2 Protein tyrosine Kinase 2 (PTK2) interaction partners

  1. both UFH and LMWH, through a FAK/actin cytoskeleton axis, promoted the adhesion and migration of B6FS fibrosarcoma cells

  2. AURKA (show AURKA ELISA Kits) may induce EMT (show ITK ELISA Kits) to promote metastasis via activation of the FAK/PI3K (show PIK3CA ELISA Kits) pathway in LSCC.

  3. Lunasin suppresses the metastasis of breast cancer cells through integrin-mediated FAK/Akt (show AKT1 ELISA Kits)/ERK (show EPHB2 ELISA Kits) and NF-kappaB (show NFKB1 ELISA Kits) signaling pathways followed by downregulation of the activity and expression of MMP-2 (show MMP2 ELISA Kits)/-9.

  4. FAK and FAK[pY397] were overexpressed in human UM tumors compared to normal ocular tissue and high levels of FAK[pY397] were seen in the most aggressive UM cell lines.

  5. Upregulated expression of FAK is associated with hepatocellular carcinoma.

  6. ITGB4 (show ITGB4 ELISA Kits) is overexpressed in hepatocellular carcinoma tissues and promotes metastases of HCC (show FAM126A ELISA Kits) by conferring anchorage independence through EGFR (show EGFR ELISA Kits)-dependent FAK-AKT (show AKT1 ELISA Kits) activation.

  7. Data show that rab5 (show RAB5A ELISA Kits) GTP-Binding Protein (Rab5a (show RAB5A ELISA Kits)) is overexpressed in human hepatocellular carcinoma (HCC (show FAM126A ELISA Kits)) and contributes to cancer cell proliferation and invasion through regulation of FAK and AKT (show AKT1 ELISA Kits) signaling.

  8. LEFTY2 (show LEFTY2 ELISA Kits) down-regulates MKi67 (show MKI67 ELISA Kits) expression and FAK activity, up-regulates miR (show MLXIP ELISA Kits)-200a and E-cadherin (show CDH1 ELISA Kits), and is thus a powerful negative regulator of endometrial cell proliferation and migration.

  9. Calcium lactate (2.5 mM), alone and in combination with 5-FU, exerted antitumor activity against both anchored and unanchored colorectal cells via calcium-mediated FAK proteolysis and inhibition of EMT (show ITK ELISA Kits) markers, such as vimentin (show VIM ELISA Kits) and SNAIL (show SNAI1 ELISA Kits).

  10. From our data we conclude that targeting of CXCR4 (show CXCR4 ELISA Kits) and FAK may overcome ABCB1 (show ABCB1 ELISA Kits) and ABCC1 (show ABCC1 ELISA Kits)-dependent doxorubicin resistance in non-small cell lung carcinoma cells

Xenopus laevis PTK2 Protein tyrosine Kinase 2 (PTK2) interaction partners

  1. FAK is required for external force-induced spindle reorientation, suggesting that FAK's involvement in this process stems from a role in the transduction of external forces to the cell cortex.

  2. FAK is required for tension-dependent organization of collective cell movements in Xenopus mesendoderm.

  3. work identifies new roles for the FERM domain in the regulation of the dynamics of FAK on its signaling complexes in vivo and in vitro and identifies epiboly as the earliest developmental process in which FAK plays a crucial role during development

  4. These data suggest an important role for the FERM domain in the activation of FAK.

  5. FAK phosphorylation at Y861 is essential for lamellipodial protrusion induced by BDNF (show BDNF ELISA Kits), while phosphorylation at Y925 controls the rate of point contact turnover.

  6. Data imply that FAK plays an essential role in chamber outgrowth and looping morphogenesis.

  7. FAK is required for proper topographic positioning of retinal axons along the anterior-posterior axis of the optic tectum in Xenopus and zebrafish, a guidance decision mediated in part by A-type ephrins.

Mouse (Murine) PTK2 Protein tyrosine Kinase 2 (PTK2) interaction partners

  1. FAK promotes nascent integrin adhesions (NA) assembly and timely turnover to couple lamellipodial protrusion to adhesions for efficient advance of the leading edge. Phosphorylation on Y397 of FAK promotes dense NA formation but is dispensable for transient NA stabilization and leading edge advance.

  2. this manuscript shows that endothelial cell FAK activity induces VCAM-1 (show VCAM1 ELISA Kits) expression and contributes to atherosclerosis

  3. FAK activation is necessary for the promotion of osteogenesis induced by extracorporeal shockwave.

  4. Data show that the essential oil (EO) decreased focal adhesion and invadopodia formation which was accompanied by a drastic downregulation of focal adhesion kinase (FAK) and proto-oncogene protein Src.

  5. results suggest that LPS (show TLR4 ELISA Kits)-stimulated macrophage mediators attenuate both FAK and Src (show SRC ELISA Kits) activations in osteoblast, suggesting a novel role for TNFalpha (show TNF ELISA Kits) on osteoblast performance

  6. Report phosphorylation sites in focal adhesion kinase and putative new binding partners.

  7. data indicate that PTPalpha (show PTPRA ELISA Kits) and FAK, which are enriched in FAs (show FAS ELISA Kits), interact with IP3R1 (show ITPR1 ELISA Kits) at adjacent ER sites to spatially sequester IL-1 (show IL1A ELISA Kits)-induced Ca(2 (show CA2 ELISA Kits)+) signalling

  8. FAK-regulated signalling module PDK1 (show PDPK1 ELISA Kits)-Akt (show AKT1 ELISA Kits)-p70S6K (show RPS6KB1 ELISA Kits) that controls Src's intracellular trafficking operates at Src (show SRC ELISA Kits)-containing autophagosomes.

  9. Data show that active active focal adhesion kinase (FAK) localizes to integrin-containing endosomes.

  10. FAK deletion correlates with increased phosphorylation of Tks-5 (tyrosine kinase substrate (show IRS2 ELISA Kits) with five SH3 domain (show ITSN1 ELISA Kits)) and reactive oxygen species production.

Cow (Bovine) PTK2 Protein tyrosine Kinase 2 (PTK2) interaction partners

  1. RhoA (show RHOA ELISA Kits) and membrane fluidity mediates the spatially polarized Src (show SRC ELISA Kits)/FAK activation in response to shear stress.

  2. XIAP (show XIAP ELISA Kits) plays an essential role in shear stress-stimulated FAK phosphorylation.

  3. mitochondrial oxidants generated in response to endothelial strain trigger FAK phosphorylation through a signaling pathway that involves protein kinase C (show PKC ELISA Kits)

  4. These results suggest that TGF-beta1 (show TGFB1 ELISA Kits)-induced monolayer permeability involves focal adhesion and cytoskeletal rearrangement through both FAK/Src (show SRC ELISA Kits)-dependent and -independent pathways.

  5. Results suggest focal adhesion kinase is involved in thrombospondin-1 (show THBS1 ELISA Kits)-induced vascular smooth muscle cell migration.

FAK (PTK2) Antigen Profile

Antigen Summary

This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined.

Alternative names and synonyms associated with FAK (PTK2)

  • PTK2 protein tyrosine kinase 2 (PTK2) Elisa Kit
  • protein tyrosine kinase 2 (PTK2) Elisa Kit
  • protein tyrosine kinase 2 (Ptk2) Elisa Kit
  • protein tyrosine kinase 2 (ptk2) Elisa Kit
  • PTK2 protein tyrosine kinase 2 (Ptk2) Elisa Kit
  • Fadk Elisa Kit
  • FAK Elisa Kit
  • FAK1 Elisa Kit
  • FRNK Elisa Kit
  • mKIAA4203 Elisa Kit
  • p125FAK Elisa Kit
  • pp125FAK Elisa Kit
  • PPP1R71 Elisa Kit

Protein level used designations for PTK2

FADK 1 , FAK-related non-kinase polypeptide , PTK2 protein tyrosine kinase 2 , focal adhesion kinase 1 , focal adhesion kinase-related nonkinase , protein phosphatase 1 regulatory subunit 71 , protein phosphatase 1, regulatory subunit 71 , pp125FAK , protein-tyrosine kinase 2 , focal adhesion kinase pp125FAK , focal ashension kinase 1 , p41/p43FRNK , focal adhesion kinase

GENE ID SPECIES
100058245 Equus caballus
5747 Homo sapiens
25614 Rattus norvegicus
399286 Xenopus laevis
14083 Mus musculus
396416 Gallus gallus
475108 Canis lupus familiaris
506270 Bos taurus
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