Browse our DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39 Proteins (DDX39)

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DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39 Proteins (DDX39)
On are 5 DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39 (DDX39) Proteins from 3 different suppliers available. Additionally we are shipping DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39 Antibodies (20) and many more products for this protein. A total of 30 DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39 products are currently listed.
2610307C23Rik, Bat1, Bat1a, D6S81E, DDX39, Ddx39a, DDXL, dxd39, MGC53693, MGC53944, MGC130793, p47, UAP56, URH49
list all proteins Gene Name GeneID UniProt
Mouse DDX39 DDX39 68278 Q8VDW0
DDX39 7919 Q13838
Rat DDX39 DDX39 114612 Q63413

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DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39 Proteins (DDX39) by Origin

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Top referenced DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39 Proteins

  1. Human DDX39 Protein expressed in Escherichia coli (E. coli) - ABIN667213 : Fleckner, Zhang, Valcárcel, Green: U2AF65 recruits a novel human DEAD box protein required for the U2 snRNP-branchpoint interaction. in Genes & development 1997 (PubMed)
    Show all 2 references for 667213

More Proteins for DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39 Interaction Partners

Xenopus laevis DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39 (DDX39) interaction partners

  1. RNA helicase Ddx39 is expressed in the developing central nervous system, limb, otic vesicle, branchial arches and facial mesenchyme of Xenopus laevis.

Mouse (Murine) DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39 (DDX39) interaction partners

  1. The expression of DDX39 in gemcitabine-sensitive KLM1 and -resistant KLM1-R cells was compared.

  2. Mx proteins exert their antiviral activity against IAV by interfering with the function of the RNA helicases UAP56 (show DDX39B Proteins) and URH49

  3. Regulation of URH49 mRNA expression and comparison with the related UAP56 (show DDX39B Proteins) RNA helicase.

Human DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39 (DDX39) interaction partners

  1. Study showed that a genetic variant in the 5' UTR of DDX39B reduces translation of DDX39B mRNAs and increases multiple sclerosis (MS) risk. Importantly, this DDX39B variant showed strong genetic & functional epistasis with allelic variants in IL7R (show IL7R Proteins) exon 6; study establishes the occurrence of biological epistasis in humans & provides mechanistic insight into the regulation of IL7R (show IL7R Proteins) exon 6 splicing & its impact on MS risk.

  2. DDX39B and its paralog DDX39A regulate androgen receptor (show AR Proteins) splice variant AR-V7 generation

  3. Distinct features of RNA influence and ATPase efficiency between UAP56 (show DDX39B Proteins) and TcSub2 may reflect distinct structures for functional sites of TcSub2. For this reason, ligand-based or structure-based methodologies can be applied to investigate the potential of TcSub2 as a target for new drugs.

  4. However, no significant association was observed between the DDX39B -22 G/C polymorphism in the cases and controls. Furthermore, it is clarified that the protective effect of IL-4 (show IL4 Proteins) -590 is independent from APOE (show APOE Proteins) protective genotypes

  5. The G allele of DDX39B-22C > G was associated with absent or decreased manifestations of vivax malaria and the C allele was a risk factor for disease complications.

  6. We unravel the role of unexplored immunologically important genes, BAT1 and BTNL2 (show BTNL2 Proteins), and the haplotypes of the significantly associated SNPs therein, to understand susceptibility to the disease, leprosy and its differential severity.

  7. these data identify UAP56 (show DDX39B Proteins) as an important binding partner of Bcr (show BCR Proteins) and a novel target for inhibiting vascular smooth muscle cell proliferation.

  8. UAP56 (show DDX39B Proteins) and URH49 exhibit an intrinsic CRM1 (show XPO1 Proteins)-independent nucleocytoplasmic shuttling

  9. Mx proteins exert their antiviral activity against IAV by interfering with the function of the RNA helicases UAP56 (show DDX39B Proteins) and URH49

  10. In summary, these data demonstrate that UAP56 (show DDX39B Proteins) is utilized by influenza A viruses to prevent the formation of dsRNA and, hence, the activation of the innate immune response.

DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39 (DDX39) Protein Profile

Protein Summary

This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and it also plays an important role in mRNA export from the nucleus to the cytoplasm. This gene belongs to a cluster of genes localized in the vicinity of the genes encoding tumor necrosis factor alpha and tumor necrosis factor beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on both chromosomes 6 and 11. Read-through transcription also occurs between this gene and the upstream ATP6V1G2 (ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2) gene.

Alternative names and synonyms associated with DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39 (DDX39)

  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 (ddx39)
  • nuclear RNA helicase (ddx39)
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 (DDX39)
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A (DDX39A)
  • ATP-dependent RNA helicase DDX39 (ddx39)
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 39b (ddx39b)
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 (Ddx39)
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B (ddx39b)
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B (DDX39B)
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B (Ddx39b)
  • 2610307C23Rik protein
  • Bat1 protein
  • Bat1a protein
  • D6S81E protein
  • DDX39 protein
  • Ddx39a protein
  • DDXL protein
  • dxd39 protein
  • MGC53693 protein
  • MGC53944 protein
  • MGC130793 protein
  • p47 protein
  • UAP56 protein
  • URH49 protein

Protein level used designations for DDX39

DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 , nuclear RNA helicase , ATP-dependent RNA helicase DDX39 , ATP-dependent RNA helicase DDX39A , DEAD box protein 39 , DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 39 , UAP56-related helicase, 49 kDa , HLA-B associated transcript 1 , 56 kDa U2AF65-associated protein , ATP-dependent RNA helicase p47 , HLA-B-associated transcript 1 protein , nuclear RNA helicase (DEAD family) , spliceosome RNA helicase BAT1 , spliceosome RNA helicase DDX39B , DEAD box protein UAP56 , DEADD box protein , D17H6S81E-1 , D20H6S81e , HLA-B associated transcript 1A , HLA-B-associated transcript 1A , Nuclear RNA helicase , spliceosome RNA helicase Bat1 , spliceosome RNA helicase Ddx39b

379310 Xenopus laevis
380425 Xenopus laevis
455783 Pan troglodytes
476689 Canis lupus familiaris
548754 Xenopus (Silurana) tropicalis
718822 Macaca mulatta
100196350 Salmo salar
100084960 Ornithorhynchus anatinus
100194522 Salmo salar
68278 Mus musculus
447706 Xenopus laevis
7919 Homo sapiens
474839 Canis lupus familiaris
448813 Sus scrofa
540191 Bos taurus
114612 Rattus norvegicus
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