Browse our DDX3X Proteins (DDX3X)

Full name:
DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked Proteins (DDX3X)
On are 5 DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X) Proteins from 3 different suppliers available. Additionally we are shipping DDX3X Antibodies (220) and DDX3X Kits (3) and many more products for this protein. A total of 239 DDX3X products are currently listed.
An3, D1Pas1-rs2, DBX, Ddx3, DDX3X, Ddx3y, DDX14, Fin14, HLP2, pl10
list all proteins Gene Name GeneID UniProt
DDX3X 1654 O00571
Rat DDX3X DDX3X 317335  
DDX3X 13205 Q62167

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DDX3X Proteins (DDX3X) by Origin

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Top referenced DDX3X Proteins

  1. Human DDX3X Protein expressed in HEK-293 Cells - ABIN2719282 : Lin, Sivakumaran, Jones, Li, Harper, Wei, Jin, Rustanti, Meunier, Spann, Harrich: A HIV-1 Tat mutant protein disrupts HIV-1 Rev function by targeting the DEAD-box RNA helicase DDX1. in Retrovirology 2015 (PubMed)

More Proteins for DDX3X Interaction Partners

Human DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X) interaction partners

  1. Data suggest that DEAD-box helicase 3 (DDX3X) physically interacts and co-localizes with poly(A)-binding cytoplasmic protein (show BLZF1 Proteins) 1 (PABPC1 (show PABPC1 Proteins)) and caprin-1 in lamellipodia at the leading edge of spreading cells; these interactions are dependent on mRNA; depletion of DDX3X (via gene silencing with the CRISPR-Cas (show CSE1L Proteins) system) leads to decreased cell motility. These studies were conducted using MRC5 lung fibroblast cell line.

  2. The article describes RNA remodeling activity of human DDX3X and Caenorhabditis elegans LAF (show HPD Proteins)-1 tuned by protein concentration, RNA length, and ATP.

  3. the role of DDX3 in sarcomas

  4. DDX3 directly regulates TRAF3 (show TRAF3 Proteins) ubiquitination and acts as a scaffold to co-ordinate assembly of signaling complexes downstream from MAVS (show MAVS Proteins).

  5. Here we identify the DEAD-box helicase 3 (DDX3) as a novel interaction partner of Y. enterocolitica YopM and present the three-dimensional structure of a YopM:DDX3 complex

  6. Here, the authors show that herpes simplex virus 1 gene expression, replication, and propagation depend on optimal DDX3X protein levels.

  7. de novo heterozygous DDX3X variants should be considered not only in females with unexplained ID, but also in individuals with a clinical diagnosis of T-CS.

  8. high metastatic DDX3 expression correlates with worse survival, implying that DDX3 is a potential therapeutic target in metastatic breast cancer, in particular in the clinically important group of TN patients.

  9. Herein, we showed for the first time, to our knowledge, that the inhibition of DDX3 by a small molecule could be successfully exploited for the development of a broad spectrum antiviral agent.

  10. Data show that knockdown of RNA helicase DDX3 in breast cancer MCF-7 and MDA-MB-231 cells resulted in decreased proliferation rates.

Mouse (Murine) DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X) interaction partners

  1. This study demonstrated that DDX3 regulates the translation of both Prkaca and Rac1 mRNAs in neurons and therefore maintains the PKA-Rac1 signaling axis at neurite terminals for both neurite outgrowth and dendritic spine formation.

  2. Targeted Ddx3x ablation in the epiblast leads to widespread apoptosis and abnormal growth, which causes embryonic lethality in the Sox2-cre/+;Ddx3x(flox)/Y mutant around E11.5.These results have uncovered that mouse Ddx3x is essential for both embryo and extraembryonic development

DDX3X Protein Profile

Protein Summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which interacts specifically with hepatitis C virus core protein resulting a change in intracellular location. This gene has a homolog located in the nonrecombining region of the Y chromosome. The protein sequence is 91% identical between this gene and the Y-linked homolog. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with DDX3X

  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked (DBX)
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked (DDX3X)
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked (ddx3x)
  • DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked (DDX3X)
  • DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked (Ddx3x)
  • DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked (ddx3x)
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 3 (Ddx3)
  • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked (Ddx3x)
  • An3 protein
  • D1Pas1-rs2 protein
  • DBX protein
  • Ddx3 protein
  • DDX3X protein
  • Ddx3y protein
  • DDX14 protein
  • Fin14 protein
  • HLP2 protein
  • pl10 protein

Protein level used designations for DDX3X

DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked , DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 , ATP-dependent RNA helicase DDX3X-like , ATP-dependent RNA helicase DDX3X , CAP-Rf , DEAD box protein 3, X-chromosomal , DEAD box, X isoform , DEAD/H box-3 , helicase like protein 2 , helicase-like protein 2 , DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked , ATP-dependent RNA helicase DDX3Y , DEAD (Asp-Glu-Ala-Asp) box polypeptide 3 Y-linked , D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 3 , D1Pas1-related sequence 2 , DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 3 , DEAD box RNA helicase DEAD3 , DEAD-box protein 3 (DEAD-box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1PAS1 related sequence 2) , embryonic RNA helicase , fibroblast growth factor inducible 14 , mDEAD3

448820 Sus scrofa
702315 Macaca mulatta
706891 Macaca mulatta
100028065 Monodelphis domestica
100082235 Ornithorhynchus anatinus
100348597 Oryctolagus cuniculus
100399667 Callithrix jacchus
100446823 Pongo abelii
100464548 Ailuropoda melanoleuca
100544480 Meleagris gallopavo
100555462 Anolis carolinensis
1654 Homo sapiens
317335 Rattus norvegicus
379975 Xenopus laevis
100312982 Rattus norvegicus
480886 Canis lupus familiaris
418567 Gallus gallus
510093 Bos taurus
13205 Mus musculus
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