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Suggest that during heart disease nucleolin is reactivated to mobilize conserved aspects of chromatin remodeling and gene expression.
Disruption of the AtNUC-L1 gene induces loss of symmetrical DNA methylation (show HELLS ELISA Kits) without affecting histone epigenetic marks at rRNA genes.
PARL1 protein has roles similar to those of the yeast nucleolin in nuclear signal recognition, ribosomal processing, and ribosomal subunit accumulation.
C23 on the cell surface may be a kind of indispensable component in activation of EGFR signaling, by which C23 can participate in the growth and invasion of cervical tumors
These data suggest that nucleolin could be an effective treatment target and prognostic factor for patients with non-small cell lung cancer
These findings demonstrate that nucleolin expression is down-regulated by miR (show MLXIP ELISA Kits)-194 and miR (show MLXIP ELISA Kits)-206 and upregulated by HuR (show ELAVL1 ELISA Kits).
Nucleolin overexpression is associated with ependymoma.
Nucleolin stabilizes oncostatin-M (show OSM ELISA Kits) mRNA by binding to a GC-rich (show RELB ELISA Kits) element in its 3'UTR (show UTS2R ELISA Kits).
Data show that nucleolin (NCL) antagonist N6L inhibits cell growth with different sensitivity depending to NCL (show CLN5 ELISA Kits) localization.
HAUSP (show USP7 ELISA Kits)-nucleolin interaction is regulated by p53 (show TP53 ELISA Kits)-Mdm2 (show MDM2 ELISA Kits) complex in response to DNA damage.
These results suggested a clear link between nucleolin expression (including cell membrane nucleolin) and the stem cell-like phenotype in breast cancer, namely in the triple negative molecular subtype.
Identification of NCL (show CLN5 ELISA Kits) as a prominent host factor capable of binding with high affinity to the G4 structures present in the LTR promoter of HIV-1.
NCL (show CLN5 ELISA Kits) overexpression is involved in liver carcinogenesis.
Nucleolin Acts as a Scavenger Receptor for Acetylated Low-Density Lipoprotein on Macrophages
Nucleolin is a receptor for maleylated-bovine serum albumin (show ALB ELISA Kits) on macrophages
Lrrc34, a novel nucleolar protein (show MCRS1 ELISA Kits), interacts with npm1 (show GJA1 ELISA Kits) and ncl and has an impact on pluripotent stem cells
results indicate that nucleolin is a receptor that allows macrophages to recognize toxic Advanced glycosylation end-products.
results for the first time demonstrate that nucleolin-SUMO at K294R plays a critical role in its nucleus sequestration and gadd45alpha (show GADD45A ELISA Kits) mRNA binding activity.
Nucleolin-FGF1 interaction is critical for the intranuclear phosphorylation of FGF1 by PKCdelta and thereby the regulation of nuclear export of FGF1.
ANKRD1 (show ANKRD1 ELISA Kits), in association with factors such as nucleolin, represses MMP13 (show MMP13 ELISA Kits) transcription. Ankrd1 (show ANKRD1 ELISA Kits) deletion additionally relieved MMP10 (show MMP10 ELISA Kits) transcriptional repression
Nucleolin is involved in the regulation of ischemia reperfusion-induced cardiac injury and dysfunction via the regulation of Hsp32 (show HMOX1 ELISA Kits).
Data indicate that increased expression of interleukin-9 receptor (Il9R (show IL9R ELISA Kits)) is associated with an increased binding of nucleolin.
Data show that si-RNA induced down-regulation of FUT1 (show FUT1 ELISA Kits) and FUT2 (show FUT2 ELISA Kits) reduced expression of fucosylated nucleolin glycoforms and their exposure at the cell surface.
Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. The intron 11 of the NCL gene encodes a small nucleolar RNA, termed U20.
, eukaryotic translation initiation factor 3 subunit A
, Eukaryotic translation initiation factor 3 subunit 10
, nucleolin-like protein
, protein C23