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ATPase Type 13A2 Proteins (ATP13A2)
On www.antibodies-online.com are 9 ATPase Type 13A2 (ATP13A2) Proteins from 2 different suppliers available. Additionally we are shipping ATP13A2 Antibodies (66) and ATP13A2 Kits (7) and many more products for this protein. A total of 83 ATP13A2 products are currently listed.
Synonyms:
1110012E06Rik, AA589443, ATP13A2, CLN12, HSA9947, im:7147302, KRPPD, PARK9, RGD1307977, zgc:136762
list all proteins Gene Name GeneID UniProt
Rat ATP13A2 ATP13A2 362645  
ATP13A2 23400 Q9NQ11
ATP13A2 74772 Q9CTG6

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Zebrafish ATPase Type 13A2 (ATP13A2) interaction partners

  1. Thsi stduy Our findings bring new insight into the biology of ATP13A2 and open novel opportunities for its study using zebrafish as a model organism.

Human ATPase Type 13A2 (ATP13A2) interaction partners

  1. we describe, for the first time, the deleterious effect arising from the interaction between the ATP13A2 familial mutant Dup22 with a-Syn (show FYN Proteins). We show that this ATP13A2 mutant can enhance a-Syn (show FYN Proteins) oligomerization and aggregation in cell culture

  2. ATP13A2 inhibition by hsa (show CD24 Proteins)-miR (show MLXIP Proteins)-4306 efficiently restored manganese-induced cytotoxicity in cultured neurons.

  3. This study demonstrated that loss of ATP13A2 function causes a combination of lysosomal and mitochondrial dysfunction that affects multiple neuronal populations.

  4. The ATP13A2 A746T variant is rare in Han Chinese patients and controls and is not associated with PD susceptibility in this ethnic group.

  5. This study showed that LRRK2 (show LRRK2 Proteins), PARK2 (show PARK2 Proteins) and ATP13A2 are under copy number variations influence in patient with Parkinson disease.

  6. tre (show TREH Proteins) results of this study suggests that the expression of ATP13A2 regulated by the PHD2 (show EGLN1 Proteins)-HIF1alpha (show HIF1A Proteins) signaling pathway,and this is instrumental in maintaining cellular iron homeostasis and cell viability in mitochondrially compromised DAergic neurons.

  7. that ATP13A2 contains a unique N-terminal hydrophobic extension that lies on the cytosolic membrane surface of the lysosome, where it interacts with the lysosomal signaling lipids phosphatidic acid and phosphatidylinositol(3,5)bisphosphate.

  8. ATP13A2 overexpression improves the lysosome membrane integrity and protects against iron-induced cell damage.

  9. A review of recent advances in the emerging association of ATP13A2 mutations with Parkinsonism and neuronal ceroid lipofuscinoses.

  10. The mutation rates of Thr12Met and Ala1144Thr of ATP13A2 in the Uygur and Han Parkinson's disease patients in the Xinjiang region are low.

Mouse (Murine) ATPase Type 13A2 (ATP13A2) interaction partners

  1. the loss of Atp13a2 causes sensorimotor impairments, alpha-synuclein accumulation as occurs in PD and related synucleinopathies, and accumulation of lipofuscin deposits characteristic of NCL (show NCL Proteins)

  2. study reveals a number of intriguing neuronal phenotypes due to the loss- or gain-of-function of ATP13A2 that support a role for this protein in regulating intracellular cation homeostasis and neuronal integrity

  3. This study showed that ATP13A2 regulates mitochondrial bioenergetics through macroautophagy.

ATP13A2 Protein Profile

Protein Summary

This gene encodes a member of the P5 subfamily of ATPases which transports inorganic cations as well as other substrates. Mutations in this gene are associated with Kufor-Rakeb syndrome (KRS), also referred to as Parkinson disease 9. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with ATP13A2

  • ATPase type 13A2 (Atp13a2)
  • ATPase type 13A2 (ATP13A2)
  • ATPase type 13A2 (atp13a2)
  • ATPase type 13A2 (PTRG_01071)
  • ATPase type 13A2 (MCYG_01937)
  • ATPase type 13A2 (LOC100222246)
  • ATPase type 13A2 (LOC100344893)
  • ATPase type 13A2 (LOC100358965)
  • ATPase type 13A2 (PGTG_17045)
  • 1110012E06Rik protein
  • AA589443 protein
  • ATP13A2 protein
  • CLN12 protein
  • HSA9947 protein
  • im:7147302 protein
  • KRPPD protein
  • PARK9 protein
  • RGD1307977 protein
  • zgc:136762 protein

Protein level used designations for ATPase Type 13A2 Proteins (ATP13A2)

probable cation-transporting ATPase 13A2 , ATPase type 13A2 , N-ATPase , probable cation-transporting ATPase 13A2-like , putative ATPase

GENE ID SPECIES
362645 Rattus norvegicus
419466 Gallus gallus
456525 Pan troglodytes
510792 Bos taurus
568666 Danio rerio
699678 Macaca mulatta
100053155 Equus caballus
6338252 Pyrenophora tritici-repentis Pt-1C-BFP
9229055 Arthroderma otae CBS 113480
100026165 Monodelphis domestica
100222246 Taeniopygia guttata
100344893 Oryctolagus cuniculus
100358965 Oryctolagus cuniculus
100439053 Pongo abelii
100523971 Sus scrofa
10530751 Puccinia graminis f. sp. tritici CRL 75-36-700-3
23400 Homo sapiens
74772 Mus musculus
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