Browse our ATP2B3 Proteins (ATP2B3)

On www.antibodies-online.com are 4 ATPase, Ca++ Transporting, Plasma Membrane 3 (ATP2B3) Proteins from 1 different suppliers available. Additionally we are shipping ATP2B3 Antibodies (16) and many more products for this protein. A total of 24 ATP2B3 products are currently listed.
Synonyms:
6430519O13Rik, atp2b2, atp2b3, mxra1, Pmca3, pmca3a, pmca4, pmca4b, pmca4x, SCAX1, zgc:92885
list all proteins Gene Name GeneID UniProt
ATP2B3 492 Q16720
Rat ATP2B3 ATP2B3 29599 Q64568
Mouse ATP2B3 ATP2B3 320707  

ATP2B3 Proteins (ATP2B3) by Origin

More Proteins for ATP2B3 Interaction Partners

Human ATPase, Ca++ Transporting, Plasma Membrane 3 (ATP2B3) interaction partners

  1. In summary, the APA (show ENPEP Proteins)-associated ATP2B3(Leu425_Val426del) mutant promotes aldosterone production by at least 2 different mechanisms: 1) a reduced Ca(2 (show CA2 Proteins)+) export due to the loss of the physiological pump function; and 2) an increased Ca(2 (show CA2 Proteins)+) influx due to opening of depolarization-activated Ca(2 (show CA2 Proteins)+) channels as well as a possible Ca(2 (show CA2 Proteins)+) leak through the mutated pump.

  2. Mutations in ATP2B3 gene is associated with aldosterone-producing adenomas.

  3. Different mutations (KCNJ5 (show KCNJ5 Proteins), ATP1A1 (show ATP1A1 Proteins), ATP2B3, and CACNA1D (show CACNA1D Proteins)) are found in different aldosterone-producing nodules from the same adrenal, suggesting that somatic mutations are independent events triggered by mechanisms that remain to be identified.

  4. Novel PMCA3 missense mutation co-occurring with a heterozygous mutation in LAMA1 (show LAMA1 Proteins) impaired cellular Ca2 (show CA2 Proteins)+ homeostasis in patients with Cerebellar Ataxia (show USP14 Proteins).

  5. Somatic mutations found in KCNJ5 (show KCNJ5 Proteins), ATP1A1 (show ATP1A1 Proteins), and ATP2B3 appear to be the driving forces for a higher aldosterone production and proliferations of glomerulosa cells.

  6. ATP2B3 mutations are present in aldosterone-producineg adenomas that result in an increase in CYP11B2 (show CYP11B2 Proteins) gene expression and may account for the dysregulated aldosterone production in a subset of patients with sporadic primary aldosteronism.

  7. Somatic mutations in ATP2B3 gene leads to aldosterone-producing adenomas and secondary hypertension.

  8. Mutation of plasma membrane Ca2+ ATPase isoform 3 in a family with X-linked congenital cerebellar ataxia (show USP14 Proteins) impairs Ca2 (show CA2 Proteins)+ homeostasis.

  9. role in the intracellular Ca(2 (show CA2 Proteins)+) extrusion of syncytiotrophoblast-like structure originating from the differentiation of cultured trophoblast cells isolated from human term placenta

  10. Expression of the placental calcium transporter PMCA3 mRNA predicts neonatal whole body bone mineral content

ATP2B3 Protein Profile

Protein Summary

The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 3. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with ATP2B3

  • ATPase, Ca++ transporting, plasma membrane 3 (ATP2B3)
  • ATPase, Ca++ transporting, plasma membrane 3 (atp2b3)
  • ATPase, Ca++ transporting, plasma membrane 3 (Atp2b3)
  • ATPase, Ca++ transporting, plasma membrane 3a (atp2b3a)
  • ATPase, Ca++ transporting, plasma membrane 4 (atp2b4)
  • 6430519O13Rik protein
  • atp2b2 protein
  • atp2b3 protein
  • mxra1 protein
  • Pmca3 protein
  • pmca3a protein
  • pmca4 protein
  • pmca4b protein
  • pmca4x protein
  • SCAX1 protein
  • zgc:92885 protein

Protein level used designations for ATP2B3

ATPase, Ca++ transporting, plasma membrane 3 , plasma membrane calcium ATPase-like , plasma membrane calcium ATPase , plasma membrane calcium pump , plasma membrane calcium-transporting ATPase 3 , plasma membrane calcium ATPase 3 , plasma membrane calcium ATPase 3a

GENE ID SPECIES
100078819 Ornithorhynchus anatinus
100125191 Xenopus (Silurana) tropicalis
100374040 Saccoglossus kowalevskii
695803 Macaca mulatta
100551522 Anolis carolinensis
100584463 Nomascus leucogenys
100639471 Amphimedon queenslandica
492 Homo sapiens
29599 Rattus norvegicus
492238 Canis lupus familiaris
320707 Mus musculus
504353 Bos taurus
100356760 Oryctolagus cuniculus
436745 Danio rerio
446855 Xenopus laevis
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