Browse our Peroxiredoxin 3 Proteins (PRDX3)

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Peroxiredoxin 3 Proteins (PRDX3)
On are 27 Peroxiredoxin 3 (PRDX3) Proteins from 12 different suppliers available. Additionally we are shipping Peroxiredoxin 3 Antibodies (153) and Peroxiredoxin 3 Kits (11) and many more products for this protein. A total of 203 Peroxiredoxin 3 products are currently listed.
AOP-1, Aop1, AW822249, cb718, D0Tohi1, Ef2l, HBC189, Mer5, MGC83969, MTAP, PRDX3, PRO1748, prx-III, Prx3, SP-22, SP22, TDXM, wu:fk49e09, zgc:110282, zgc:112512
list all proteins Gene Name GeneID UniProt
PRDX3 10935 P30048
PRDX3 11757 P20108
PRDX3 64371 Q9Z0V6

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Peroxiredoxin 3 Proteins (PRDX3) by Origin

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Top referenced Peroxiredoxin 3 Proteins

  1. Human PRDX3 Protein expressed in Escherichia coli (E. coli) - ABIN667738 : Cox, Peskin, Paton, Winterbourn, Hampton: Redox potential and peroxide reactivity of human peroxiredoxin 3. in Biochemistry 2009 (PubMed)
    Show all 2 references for 667738

  2. Mouse (Murine) PRDX3 Protein expressed in Escherichia coli (E. coli) - ABIN2123460 : Zhao, Du, Zhou, Liu, Gu, Long: Differences in Proinflammatory Property of Six Subtypes of Peroxiredoxins and Anti-Inflammatory Effect of Ligustilide in Macrophages. in PLoS ONE 2016 (PubMed)

More Proteins for Peroxiredoxin 3 Interaction Partners

Human Peroxiredoxin 3 (PRDX3) interaction partners

  1. Prx3 and Trx2 (show TXN2 Proteins) comprise an adaptive system to sense changes in atmospheric oxygen tension and influence cellular injury responses through both detoxification of mitochondrial oxidants and regulation of mitochondrial redox-dependent signaling

  2. PRX3 plays a crucial role in mitochondrial homeostasis.

  3. High PRX3 expression is associated with invasion of lung adenocarcinoma.

  4. We also found that forkhead box protein 1 (FOXM1 (show FOXM1 Proteins))-induced peroxiredoxin 3 (PRDX3) maintains the mitochondrial function, and the FOXM1 (show FOXM1 Proteins)/PRDX3 mitochondrial pathway maintains survival of colon CSCs

  5. Oxidative stress promotes PRX2 (show PRDX2 Proteins) and PRX3 hyperoxidation and attenuates pro-survival signaling in aging chondrocytes.

  6. the species with one disulfide and one hyperoxidized active site was decameric for Prx2 (show PRDX2 Proteins) and dimeric for Prx3. Reduction and re-oxidation of the hyperoxidized dimer of Prx3 produced hyperoxidized monomers

  7. Data indicate that peroxiredoxin III (PrxIII) is a common direct target of both miroRNAs miR (show MLXIP Proteins)-26a-5p and miR (show MLXIP Proteins)-23b-3p.

  8. Colon cancer stem cells overexpress the mitochondrial gene PRX3, which is required for maintenance of mitochondrial function and tumorigenesis, and is regulated by forkhead box protein 1, which also regulates expression of CD133 in these cells.

  9. High serum PRDX3 levels are associated with hepatocellular carcinoma.

  10. Peroxiredoxin 3 levels regulate a mitochondrial redox setpoint in malignant mesothelioma cells.

Mouse (Murine) Peroxiredoxin 3 (PRDX3) interaction partners

  1. Oxidative stress promotes PRX2 (show PRRX2 Proteins) and PRX3 hyperoxidation and attenuates pro-survival signaling in aging chondrocytes.

  2. This study showed that from E10.5,Prdx3 showed strong ventral lateral expression. This increased ventral immunotaining persisted until E18.5 but became relatively less striking at later stages.

  3. Prx3 plays a crucial role in mitochondrial homeostasis and thereby controls the contractile functions of skeletal muscle.

  4. The SirT1 (show SIRT1 Proteins) regulates the expression of several antioxidant genes in bovine aortic endothelial cells, including Mn superoxide dismutase (show SOD2 Proteins), catalase (show CAT Proteins), peroxiredoxins 3 and 5, thioredoxin 2 (show TXN2 Proteins), thioredoxin reductase 2 (show TXNRD2 Proteins), and uncoupling protein 2 (show UCP2 Proteins).

  5. Prx3 is up-regulated in response to oxidative stress; the maintenance of Prx3 levels in hair cells is a critical factor in their susceptibility to acquired hearing loss.

  6. The concerted action of PrxIII and Srx (show SRX1 Proteins) is important for protection against pyrazole-induced oxidative stress arising from the convergent induction of CYP2E1 (show CYP2E1 Proteins)-derived and ER stress-derived ROS (show ROS1 Proteins) in mitochondria.

  7. PrxIII in mouse adrenal cortex is inactivated by H(2)O(2) produced by cytochrome P450 enzymes during corticosterone production stimulated by adrenocorticotropic hormone.

  8. endogenous Prx3 may play an essential role in maintaining normal characteristics of adipocytes and that defect in Prx3 alters mitochondrial redox state and function.

  9. Immunohistochemical analysis revealed segment-specific alterations induced by the ischemic insult. Grx2 (show GRX2 Proteins), Prx3, and Prx6 (show PRDX6 Proteins) were highly expressed in proximal tubule cells

  10. Both thioredoxin 2 (show TXN2 Proteins) and glutaredoxin 2 (show GRX2 Proteins) contribute to the reduction of the mitochondrial 2-Cys (show DNAJC5 Proteins) peroxiredoxin Prx3.

Cow (Bovine) Peroxiredoxin 3 (PRDX3) interaction partners

  1. Data suggest that during ectogenesis of blastocysts infected with bovine Herpesvirus type 5, expression of AOP-1 is induced; this effect may be involved in inhibition of apoptosis in infected blastocysts/embryos.

  2. PRDX3, also known as SP-22, is a mitochondrial 2-CYS (show DNAJC5 Proteins) peroxiredoxin organized as a decameric toroid

Peroxiredoxin 3 (PRDX3) Protein Profile

Protein Summary

This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with Peroxiredoxin 3 (PRDX3)

  • peroxiredoxin 3 (prdx3)
  • peroxiredoxin 3 (PRDX3)
  • peroxiredoxin 3 (TGME49_030410)
  • peroxiredoxin 3 (Prdx3)
  • AOP-1 protein
  • Aop1 protein
  • AW822249 protein
  • cb718 protein
  • D0Tohi1 protein
  • Ef2l protein
  • HBC189 protein
  • Mer5 protein
  • MGC83969 protein
  • MTAP protein
  • PRDX3 protein
  • PRO1748 protein
  • prx-III protein
  • Prx3 protein
  • SP-22 protein
  • SP22 protein
  • TDXM protein
  • wu:fk49e09 protein
  • zgc:110282 protein
  • zgc:112512 protein

Protein level used designations for Peroxiredoxin 3 Proteins (PRDX3)

thioredoxin-dependent peroxide reductase, mitochondrial , peroxiredoxin 3 , mitochondrial thioredoxin-dependent peroxide reductase , antioxidant protein 1 , peroxiredoxin III , peroxiredoxin-3 , protein MER5 homolog , AOP-1 , Prx III , anti-oxidant protein 1 , antioxidant protein , mitochondrial Trx dependent peroxide reductase , mitochondrial thioredoxin dependent peroxide reductase , perioredoxin-3 , PRX-3 , PRx III , 5'-methylthioadenosine phosphorylase , MTA phosphorylase , MTAPase , anti-oxidant like protein-1

373079 Danio rerio
428986 Gallus gallus
444559 Xenopus laevis
702882 Macaca mulatta
741184 Pan troglodytes
7899830 Toxoplasma gondii ME49
100528928 Ictalurus punctatus
10935 Homo sapiens
11757 Mus musculus
64371 Rattus norvegicus
281998 Bos taurus
477839 Canis lupus familiaris
100174238 Pongo abelii
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