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Browse our anti-Uridine Monophosphate Synthetase (UMPS) Antibodies

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anti-Uridine Monophosphate Synthetase Antibodies (UMPS)
On www.antibodies-online.com are 32 Uridine Monophosphate Synthetase (UMPS) Antibodies from 11 different suppliers available. Additionally we are shipping Uridine Monophosphate Synthetase Proteins (8) and Uridine Monophosphate Synthetase Kits (1) and many more products for this protein. A total of 45 Uridine Monophosphate Synthetase products are currently listed.
Synonyms:
1700095D23Rik, AA408257, AL033308, BB164745, OPRT, UMPS, zgc:55702, zgc:55723
list all antibodies Gene Name GeneID UniProt
UMPS 7372 P11172
UMPS 22247 P13439
UMPS 288051  

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Most Popular Reactivities for anti-Uridine Monophosphate Synthetase (UMPS) Antibodies

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Top referenced anti-Uridine Monophosphate Synthetase Antibodies

  1. Cow (Bovine) Polyclonal UMPS Primary Antibody for WB - ABIN2783243 : Ishikawa, Kondo, Yamaguchi, Sakamoto, Fujisawa: Effect of varicocelectomy on patients with unobstructive azoospermia and severe oligospermia. in BJU international 2008 (PubMed)
    Show all 2 references for ABIN2783243

  2. Human Monoclonal UMPS Primary Antibody for IF, ELISA - ABIN521259 : Koopman, Venderbosch, van Tinteren, Ligtenberg, Nagtegaal, Van Krieken, Punt: Predictive and prognostic markers for the outcome of chemotherapy in advanced colorectal cancer, a retrospective analysis of the phase III randomised CAIRO study. in European journal of cancer (Oxford, England : 1990) 2009 (PubMed)

More Antibodies against Uridine Monophosphate Synthetase Interaction Partners

Human Uridine Monophosphate Synthetase (UMPS) interaction partners

  1. OPRT transition state analogues identify crucial components of potent inhibitors targeting OPRT enzymes.

  2. The observed mutations, aberrant splicing and downregulation of UMPS represent novel mechanisms for acquired 5-FU resistance in colorectal cancer

  3. [review] It is confirmed that the type I defect in hereditary orotic aciduria is caused by loss of uridine monophosphate (UMP)synthase activity

  4. OPRT expression in colorectal carcinoma tissues is not correlated with the toxicity of 5-FU, but OPRT expression in the normal tissues can help predict the toxicity associated with 5-FU.

  5. High expression levels of orotate phosphoribosyl transferase and thymidylate synthase (show TYMS Antibodies) in colorectal cancer appear to be significantly involved in metastasis after curative surgery

  6. Although no association was detected between UMPS variants and gastrointestinal cancer risk in Caucasians, polymerase chain reaction-RFLP with BsrI digestion and DHPLC set up at 59 degrees C are reliable and cost-effective methods to genotype UMPS.

  7. orotate phosphoribosyl transferase/DPD (show DPYD Antibodies) ratio has a relation to cancer staging and survival rate.

  8. Increased orotate phosphoribosyltransferase expression is associated with bladder cancers.

  9. expression of OPRT gene and the OPRT/dihydropyrimidine dehydrogenase (show DPYD Antibodies) ratio might be useful as predictive parameters for the efficacy of fluoropyrimidine-based chemotherapy for metastatic colorectal cancer

  10. thymidylate synthase (show TYMS Antibodies) and orotate phosphoribosyl transferase, but not dihydropyrimidine dehydrogenase (show DPYD Antibodies), are more highly expressed in prostate cancer than in benign prostatic hyperplasia

Uridine Monophosphate Synthetase (UMPS) Antigen Profile

Antigen Summary

This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with Uridine Monophosphate Synthetase (UMPS)

  • Uridine MonoPhosphate Synthetase (umps-1) antibody
  • uridine monophosphate synthetase (umps) antibody
  • uridine monophosphate synthetase (UMPS) antibody
  • uridine monophosphate synthetase (Umps) antibody
  • 1700095D23Rik antibody
  • AA408257 antibody
  • AL033308 antibody
  • BB164745 antibody
  • OPRT antibody
  • UMPS antibody
  • zgc:55702 antibody
  • zgc:55723 antibody

Protein level used designations for UMPS

Uridine MonoPhosphate Synthetase family member (umps-1) , uridine 5'-monophosphate synthase , uridine monophosphate synthetase , uridine monophosphate synthase , uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase) , OMPdecase , OPRTase , UMP synthase , orotate phosphoribosyltransferase , orotidine 5'-phosphate decarboxylase , orotate phosphoribosyl transferase and orotidine-5'-decarboxylase

GENE ID SPECIES
176453 Caenorhabditis elegans
393143 Danio rerio
494728 Xenopus laevis
100070386 Equus caballus
100353794 Oryctolagus cuniculus
100556619 Anolis carolinensis
424256 Gallus gallus
460644 Pan troglodytes
496817 Xenopus (Silurana) tropicalis
715664 Macaca mulatta
780512 Ovis aries
7372 Homo sapiens
478593 Canis lupus familiaris
281568 Bos taurus
22247 Mus musculus
288051 Rattus norvegicus
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