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Human Amphiregulin ELISA Kit for Sandwich ELISA - ABIN1889290
Shoyab, Plowman, McDonald, Bradley, Todaro: Structure and function of human amphiregulin: a member of the epidermal growth factor family. in Science (New York, N.Y.) 1989
Show all 3 references for ABIN1889290
AREG overexpression in osteoblasts induces a transient high bone mass phenotype in the trabecular compartment of the appendicular skeleton by a growth-related, non-cell autonomous mechanism
AREG-silenced keratinocytes plays an important role in regulation cell proliferation.
Hepatic CD206 (show MRC1 ELISA Kits)-positive macrophages express amphiregulin to promote the immunosuppressive activity of regulatory T cells in HBV infection.
Areg may have a role in classically activated macrophages
After activation with IL-33 (show IL33 ELISA Kits), expression of AREG is a dominant functional signature of gut (show GUSB ELISA Kits)-associated IL-33 (show IL33 ELISA Kits)-dependent group 2 innate lymphoid cells. The frequency and number of AREG-expressing ILC2s increases following intestinal injury.
AR induces hHSC fibrogenic activity via multiple mitogenic signaling pathways, and is upregulated in murine and human NASH (show SAMSN1 ELISA Kits), suggesting that AR antagonists may be clinically useful anti-fibrotics in NAFLD (show TSC2 ELISA Kits).
hormones and/or factors in addition to E that upregulate AREG can promote mammary gland development and have the potential to affect breast cancer risk associated with pubertal mammary gland development
Our data show that AREG is essential for ultraviolet therapy-induced contact hypersensitivity suppression.
Pre-maturation with cAMP modulators in conjunction with EGF (show EGF ELISA Kits)-like peptides during in vitro maturation enhances mouse oocyte developmental competence.
During high-pressure ventilation, Nrf2 (show NFE2L2 ELISA Kits) becomes activated and induces AREG, leading to a positive feedback loop between Nrf2 (show NFE2L2 ELISA Kits) and AREG, which involves the p38 MAPK (show MAPK14 ELISA Kits) and results in the expression of cytoprotective genes.
LH and AREG decrease BNP and CNP (show NPPC ELISA Kits) production in granulosa cells and down-regulate NPR2 (show NPRL2 ELISA Kits) expression in cumulus cells, which together decreased oocyte cGMP to levels that permit meiotic resumption.
cloning the complete coding region; comparison of endometrial amphiregulin mRNA expression in Meishan and White composite pigs
High expression of amphiregulin is associated with hepatocellular carcinoma.
Findings show the involvement of amphiregulin and semaphorin-3A (show SEMA3A ELISA Kits) in the improvement of skin innervations and penetration of nerve fibers into the epidermis.
Altered AREG expression induced by diverse luteinizing hormone receptor (show LHCGR ELISA Kits) reactivity in granulosa cells may provide a useful marker for oocyte developmental competency
Amphiregulin enhances alpha6beta1 integrin expression and cell motility in human chondrosarcoma cells through Ras/Raf (show RAF1 ELISA Kits)/MEK (show MAP2K1 ELISA Kits)/ERK (show EPHB2 ELISA Kits)/AP-1 (show FOSB ELISA Kits) pathway.
Our findings implicate amphiregulin as a critical mediator of the estrogen response in ERalpha (show ESR1 ELISA Kits)-positive breast cancer
Bradykinin (BK) stimulation of human airway smooth muscle cell increases amphiregulin secretion in a mechanism dependent on BK-induced COX-2 (show COX2 ELISA Kits) expression.
The applied drugs showed remarkable suppression of mTOR (show FRAP1 ELISA Kits) expression, which might delay tumor progression. Interestingly, sorafenib and sunitinib increased AREG in HNSCC 11A and 14C
Expression profiling demonstrated that AREG-activated EGFR (show EGFR ELISA Kits) regulates gene expression differently than EGF (show EGF ELISA Kits)-activated EGFR (show EGFR ELISA Kits)
This study shows that TGF-alpha (show TGFA ELISA Kits) uses common and divergent molecular mediators to regulate E-cadherin (show CDH1 ELISA Kits) expression and cell invasion.
Amphiregulin co-operates with bone morphogenetic protein 15 (show BMP15 ELISA Kits) to increase bovine oocyte developmental competence.
Data suggest that epidermal growth factor receptor (show EGFR ELISA Kits) B [ErbB (show EGFR ELISA Kits)] isoforms and their ligands (epidermal growth factor (show EGF ELISA Kits) [EGF (show EGF ELISA Kits)], amphiregulin [AREG], and neuregulin-1 (show NRG1 ELISA Kits) [NRG1 (show NRG1 ELISA Kits)]) are expressed in uteroplacental tissues in mid- and late-phases of pregnancy.
Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts.
schwannoma-derived growth factor
, amphiregulin (schwannoma-derived growth factor)
, amphiregulin long form
, colorectum cell-derived growth factor
, Schwannoma-derived growth factor
, amphiregulin B