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Human Angiopoietin 2 ELISA Kit for Sandwich ELISA - ABIN1672763
Maisonpierre, Suri, Jones, Bartunkova, Wiegand, Radziejewski, Compton, McClain, Aldrich, Papadopoulos, Daly, Davis, Sato, Yancopoulos: Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. in Science (New York, N.Y.) 1997
Show all 3 references for ABIN1672763
Mouse (Murine) Angiopoietin 2 ELISA Kit for Sandwich ELISA - ABIN1672851
Cheung, Stewart, Marsden: Endothelial Tie2/Tek ligands angiopoietin-1 (ANGPT1) and angiopoietin-2 (ANGPT2): regional localization of the human genes to 8q22.3-q23 and 8p23. in Genomics 1998
Show all 2 references for ABIN1672851
Shear stress activated Ang-2 via canonical Wnt (show WNT2 ELISA Kits) signaling in vascular endothelial cells, and Wnt (show WNT2 ELISA Kits)-Ang-2 signaling is recapitulated in zebrafish embryos with a translational implication in vascular development and repair.
miR (show MLXIP ELISA Kits)-150 is a novel suppressor of Ang2 generation with a key role in resolving vascular injury and reducing mortality resulting from sepsis.
Ang-2 blockage was beneficial as it decreased fatty streak formation and plasma triglyceride levels, but had no adverse effect on pre-existing atherosclerosis in hypercholesterolemic mice.
The results establish Ang2-mediated beta1-integrin activation as a promoter of endothelial destablization, explaining the controversial vascular functions of Ang1 (show ANGPT1 ELISA Kits) and Ang2.
Alprostadil treatment can protect renal function by reducing proteinuria. These effects are mediated, at least in part, through down-regulation of Ang-2 and IL-18 (show IL18 ELISA Kits) expression
ANG2 as the first essential regulator of the functionally important interendothelial cell-cell junctions that form during lymphatic development
This study identifies angiopoietin-2 as a link between kidney fibrosis and arterial stiffness.
vitamin D-VDR (show CYP27B1 ELISA Kits) signaling prevents lung injury by blocking the Ang-2-Tie-2 (show TEK ELISA Kits)-MLC kinase cascade and the renin (show REN ELISA Kits)-angiotensin system.
Angiopoietin-2 was expressed on lymphatic vessels and macrophages in inflamed cornea. While corneal LG response was abolished in Ang-2 knockout mice.
The Ang-1 (show ANGPT1 ELISA Kits), Ang-2, Tie-2 (show TEK ELISA Kits) system takes part in the pathologic processes in the brains that suffered acute carbon monoxide poisoning by participating in neovascularization.
Anti-angiogenic miR (show MLXIP ELISA Kits)-542-3p directly targets the key angiogenesis-promoting protein Angpt2 to prevent tumor angiogensis.
MicroRNA-30 mediates anti-inflammatory effects of shear stress and KLF2 (show KLF2 ELISA Kits) via repression of Ang2.
We conclude that ScBsAbAgn-2/TSPO targeting of glioblastoma cell lines can be achieved in vitro and in vivo.
Our results suggest that ANGPT2 is a marker of RCC (show XRCC1 ELISA Kits). Additionally, ANGPT2 and TuM2PK significantly correlated with several adverse pathological features. Further studies are needed to determine clinical applicability.
For the diagnosis of HELLP syndrome, increased levels of ET-1 (show EDN1 ELISA Kits),M30 and Angs-1 [Angiopoietin-1 (show ANGPT1 ELISA Kits)] and -2 [Angiopoietin-2]appear as promising biomarkers after determination of their standardized threshold levels
Serum and urine TNF-alpha (show TNF ELISA Kits), IL-18 (show IL18 ELISA Kits) and 8-OHdG levels increased significantly with the degree of albuminuria, and were positively correlated with increased Ang-2
Ang-2 is an independent predictor of MACE or all-cause mortality in CKD patients. Additional study is necessary in order to explore the mechanism of the association of Ang-2 with adverse outcomes in patients with CKD.
An association between the Ang-2 and T2 Diabetes mellitus with vascular complications was found.
The rs2442598 polymorphism of ANGPT2 was significantly associated with Psoriasis Vulgaris.
Angiopoietin-2 might be useful as a prognostic factor for small cell lung cancer (SCLC) and for predicting SCLC response to chemotherapy.
expression of angiopoietin 2 in the porcine metanephric kidney was observed in the podocytes of early developing glomeruli, but not in the cells near the glomerular hilus
ANGPT2 remained upregulated during maturation of glomeruli, which may be explained by the continuous growth of the glomeruli, as observed by stereological examination.
forward mandibular positioning enhance the expression of Ang1 (show ANGPT1 ELISA Kits) and Ang2 in condylar cartilage.
These results suggest that circulating Ang-2 participates in the pathogenesis of systemic inflammatory response syndrome after injury connected with early haemodynamic instability.
Hypoxic regulation of Ang-2 is HIF-dependent and demonstrate that HIF-1alpha (show HIF1A ELISA Kits) binds in human microvascular endothelial cells (HMVEC) to an evolutionary conserved Hypoxia-Responsive Element (HRE) located in the first intron of the Ang-2 gene.
Activation of the PI3-K (show PIK3CA ELISA Kits)/Akt (show AKT1 ELISA Kits) pathway downregulates Angiopoietin-2 reveals an additional mechanism through which the PTEN/PI3-K (show PIK3CA ELISA Kits)/Akt (show AKT1 ELISA Kits) pathway could affect the angiogenic process.
Ang2 produced by oscillatory shear stress in endothelial cells plays a critical role in migration/tubule formation. May have role in diseases with disturbed flow/angiogenesis.
In mature and late regressing corpus luteum, high scores of Ang-2-immunopositive endothelial and smooth muscle cells were found.
The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.
, Angiopoietin-2B (Ang-2B)