Browse our BRK1 Proteins (BRK1)

Full name:
BRICK1, SCAR/WAVE Actin-Nucleating Complex Subunit Proteins (BRK1)
On are 6 BRICK1, SCAR/WAVE Actin-Nucleating Complex Subunit (BRK1) Proteins from 3 different suppliers available. Additionally we are shipping BRK1 Antibodies (27) and and many more products for this protein. A total of 38 BRK1 products are currently listed.
6720456B07Rik, ATBRK1, AW011779, BRICK1, brk1, C3orf10, C22H3orf10, hHBrk1, HSPC300, MDS027, T9I22.8, T9I22_8
list all proteins Gene Name GeneID UniProt
Rat BRK1 BRK1 679934  
BRK1 55845 Q8WUW1
BRK1 101314 Q91VR8

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BRK1 Proteins (BRK1) by Origin

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More Proteins for BRK1 Interaction Partners

Human BRICK1, SCAR/WAVE Actin-Nucleating Complex Subunit (BRK1) interaction partners

  1. Sp1 (show PSG1 Proteins) transcriptionally regulates BRK1 expression in non-small cell lung cancer cells.

  2. We verified that NRF-1 (show NFE2L1 Proteins) positively regulates FAM134C and ENOX1 (show ENOX1 Proteins), and negatively regulates C3orf10 in human neuroblastoma (show ARHGEF16 Proteins) IMR-32 cells and primary rat cortical neurons.

  3. Data show that Brk1 downregulation results in defective directional migration and invasive growth in renal cell carcinoma cells as well as in other tumor cell types.

  4. Von Hippel-Lindau (VHL) locus deletion of the HSPC300 actin regulator gene greatly lowers risk of clear cell renal cell carcinoma (show MOK Proteins) development in Spanish VHL (show VHL Proteins) syndrome patients studied.

  5. Growing body of evidence suggesting that patients with VHL syndrome caused by large VHL deletions that include C3orf10 may be designated as having a specific subtype (Type 1B) of the disorder.

Mouse (Murine) BRICK1, SCAR/WAVE Actin-Nucleating Complex Subunit (BRK1) interaction partners

  1. Data show that genetic ablation of Brk1 results in dramatic defects in embryo compaction and development, suggesting an essential role for this protein in actin dynamics.

Arabidopsis thaliana BRICK1, SCAR/WAVE Actin-Nucleating Complex Subunit (BRK1) interaction partners

  1. BRK1 is required for accumulation of SCAR1 (show WASF1 Proteins) protein in vivo, potentially explaining the apparently essential role of BRK1 in ARP2 (show ACTR2 Proteins)/3 complex function

  2. member of the "distorted group" of trichome morphology mutants and a critical WAVE-complex subunit that selectively stabilizes the Arp2 (show ACTR2 Proteins)/3 activator SCAR2

BRK1 Protein Profile

Protein Summary

Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex (By similarity).

Alternative names and synonyms associated with BRK1

  • zgc:86903 (zgc:86903)
  • BRICK1, SCAR/WAVE actin-nucleating complex subunit (BRK1)
  • BRICK1, SCAR/WAVE actin-nucleating complex subunit (Brk1)
  • probable protein brick1 (brk1)
  • brick1 (brk1)
  • BRICK1, SCAR/WAVE actin-nucleating complex subunit (brk1-b)
  • protein BRICK 1 (BRK1)
  • 6720456B07Rik protein
  • ATBRK1 protein
  • AW011779 protein
  • BRICK1 protein
  • brk1 protein
  • C3orf10 protein
  • C22H3orf10 protein
  • hHBrk1 protein
  • HSPC300 protein
  • MDS027 protein
  • T9I22.8 protein
  • T9I22_8 protein

Protein level used designations for BRK1

probable protein BRICK1 , probable protein brick1 , GRMZM5G842058 , protein BRICK1 , probable protein BRICK1-B , BRICK1, SCAR/WAVE actin-nucleating complex subunit, homolog , haematopoietic stem/progenitor cell protein 300

415187 Danio rerio
540092 Bos taurus
679934 Rattus norvegicus
100528356 Ictalurus punctatus
542086 Zea mays
100037105 Xenopus laevis
55845 Homo sapiens
101314 Mus musculus
816795 Arabidopsis thaliana
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