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anti-Human EPH Receptor A4 Antibodies:
anti-Rat (Rattus) EPH Receptor A4 Antibodies:
anti-Mouse (Murine) EPH Receptor A4 Antibodies:
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Chicken Monoclonal EPH Receptor A4 Primary Antibody for IF, IP - ABIN967994
Becker, Gilardi-Hebenstreit, Seitanidou, Wilkinson, Charnay: Characterisation of the Sek-1 receptor tyrosine kinase. in FEBS letters 1995
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Human Monoclonal EPH Receptor A4 Primary Antibody for ELISA, WB - ABIN1724712
Walkenhorst, Dütting, Handwerker, Huai, Tanaka, Drescher: The EphA4 receptor tyrosine kinase is necessary for the guidance of nasal retinal ganglion cell axons in vitro. in Molecular and cellular neurosciences 2001
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Human Polyclonal EPH Receptor A4 Primary Antibody for IHC (p) - ABIN2473463
Theil, Frain, Gilardi-Hebenstreit, Flenniken, Charnay, Wilkinson: Segmental expression of the EphA4 (Sek-1) receptor tyrosine kinase in the hindbrain is under direct transcriptional control of Krox-20. in Development (Cambridge, England) 1998
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Mouse (Murine) Polyclonal EPH Receptor A4 Primary Antibody for IHC, ELISA - ABIN238941
Ting, Day, Spanevello, Boyd: Activation of ephrin A proteins influences Hematopoietic Stem Cell Adhesion and Trafficking patterns. in Experimental hematology 2010
findings suggest a role for EphA4 in shaping cortical oscillations during sleep that is independent from sleep need
The expression of both EphA4-FL and EphA4-N was significantly higher in the nervous tissue of SOD1 (show SOD1 Antibodies)(G93A) compared to wild-type mice suggesting that both forms are modulated during the disease process.
Findings demonstrated that mutant alpha2-chimaerin and EphA4 have different genetic interactions in distinct motor neuron pools: abducens neurons use bidirectional ephrin signaling via mutant alpha2-chimaerin to direct growth, while cervical spinal neurons use only ephrin forward signaling
The present study demonstrates that EphA4 and EphA7 (show EPHA7 Antibodies) receptors, despite their similar structure, have distinct in vivo effects on corticothalamic system projections into the ventrobasal complex /medial division of the posterior nuclear group.
These results suggest that EphA4, a novel and promising target for treatment, exacerbates EBI (show TBL1X Antibodies) through an Ephexin-1 (show NGEF Antibodies)/ROCK2 (show ROCK2 Antibodies) pathway after subarachnoid hemorrhage.
Our studies show that forward signaling through the EphA4 tyrosine kinase receptor (show KDR Antibodies), mediated by ephrins expressed by subpopulations of neuroblasts and astrocytes, is required for compact, directional organization of neuroblasts and astrocytes within the pathway and efficient transit of neuroblasts through the anterior forebrain to the olfactory bulb.
Findings suggest a putative novel mechanism for desipramine to modulate long-term potentiation through the regulation of the ephrinA3/EphA4 signaling pathway
Delineation of the specific mutation in EphA4 in this strain is important for further functional studies, such as protein-protein interactions, immunostaining and gene compensatory studies, investigating the mechanism underlying the effects of altered function of Eph (show EPHA1 Antibodies) family of receptor tyrosine kinases on phenotype.
the results of the present study demonstrated that angiogenesis occurs, and that the molecules EphA4 and ephrin-A5 (show EFNA5 Antibodies) are expressed in the hippocampal CA1 (show CA1 Antibodies) and CA3 (show CA3 Antibodies) areas throughout epileptogenesis. PECAM-1 (show PECAM1 Antibodies) may detect epileptic microvessel patterns in the hippocampi of mice and EphA4 may contribute to the microvessel plasticity via the ephrin-A5 (show EFNA5 Antibodies) signaling pathway.
results suggest that EphA4 is involved in circadian sleep regulation
the PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies), Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling pathways as well as ERK1/2 (show MAPK1/3 Antibodies) downstream of EPHA4 receptor activation, play an important role in the regulation of events related with the EMT (show ITK Antibodies) development, which may be associated with the therapeutic failure in rectal cancer after radiotherapy.
Molecular interactions of EphA4, growth hormone receptor (show GHR Antibodies), Jak2 (show JAK2 Antibodies), and STAT5B (show STAT5B Antibodies) have been described.
Reduced EphA4 expression is associated with EBV-associated B lymphoma.
No difference was found in the expression of EPHA4 in morphologically normal glands, HGPIN, or prostatic cancer.
we supposed that EphA4 interacted with CDK5 (show CDK5 Antibodies) and promoted its expression which in turn enhanced p-AKT (show AKT1 Antibodies) expression and promoted cell adhesion-mediated drug resistance in multiple myeloma.
EphA4 was reduced in breast carcinoma, which is associated with high grade, advanced TNM (show ODZ1 Antibodies) stage, lymph node metastasis, and poor outcome of patients
Host EphA4 expression regulates cancer development mainly via EphA4-mediated IGF1 (show IGF1 Antibodies) synthesis signal.
EPHA4 is overexpressed but not functionally active in Sezary syndrome.
expression of Eph (show EPHA1 Antibodies) A1, A2, A4, and A7 was strongly detected in endometrial epithelial cells during early pregnancy.
The EphA4 gene is significantly associated with litter size in pigs.
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
, EPH-like kinase 8
, TYRO1 protein tyrosine kinase
, ephrin type-A receptor 4
, receptor protein-tyrosine kinase HEK8
, tyrosine-protein kinase TYRO1
, tyrosine-protein kinase receptor SEK
, ephrin receptor epsilon
, EPH receptor A4
, ephrin receptor EphA4
, ephrin receptor EphA4-like
, ephrin type-A receptor 4-like
, tyrosine-protein kinase receptor MPK-3
, tyrosine-protein kinase receptor SEK-1
, ephrin type-A receptor 4-B
, receptor tyrosine kinase
, tyrosine-protein kinase receptor PAG
, eph receptor A3
, eph-like kinase 2
, eph-like receptor tyrosine kinase 1
, ephrin type-A receptor 4a
, tyrosine-protein kinase receptor ZEK2