Browse our EPH Receptor A4 Proteins (EPHA4)

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EPH Receptor A4 Proteins (EPHA4)
On are 28 EPH Receptor A4 (EPHA4) Proteins from 8 different suppliers available. Additionally we are shipping EPH Receptor A4 Antibodies (190) and EPH Receptor A4 Kits (12) and many more products for this protein. A total of 245 EPH Receptor A4 products are currently listed.
2900005C20Rik, AI385584, Cek8, Ci-Eph1, EPHA4, ephe, HEK8, rb, RGD1560587, rtk1, SEK, Sek1, tyr01, TYRO1
list all proteins Gene Name GeneID UniProt
EPHA4 13838 Q03137
EPHA4 2043 P54764
EPHA4 316539  

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EPH Receptor A4 Proteins (EPHA4) by Origin

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Top referenced EPH Receptor A4 Proteins

  1. Human EPH Receptor A4 Protein expressed in Human Cells - ABIN2004217 : Flanagan, Vanderhaeghen: The ephrins and Eph receptors in neural development. in Annual review of neuroscience 1998 (PubMed)
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  2. Mouse (Murine) EPH Receptor A4 Protein expressed in Human Cells - ABIN2007986 : Murai, Pasquale: 'Eph'ective signaling: forward, reverse and crosstalk. in Journal of cell science 2003 (PubMed)
    Show all 3 references for 2007986

  3. Rat (Rattus) EPH Receptor A4 Protein expressed in Human Cells - ABIN2009192 : Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ... in Genome research 2004 (PubMed)
    Show all 2 references for 2009192

More Proteins for EPH Receptor A4 Interaction Partners

Mouse (Murine) EPH Receptor A4 (EPHA4) interaction partners

  1. Findings demonstrated that mutant alpha2-chimaerin and EphA4 have different genetic interactions in distinct motor neuron pools: abducens neurons use bidirectional ephrin signaling via mutant alpha2-chimaerin to direct growth, while cervical spinal neurons use only ephrin forward signaling

  2. The present study demonstrates that EphA4 and EphA7 (show EPHA7 Proteins) receptors, despite their similar structure, have distinct in vivo effects on corticothalamic system projections into the ventrobasal complex /medial division of the posterior nuclear group.

  3. These results suggest that EphA4, a novel and promising target for treatment, exacerbates EBI (show TBL1X Proteins) through an Ephexin-1 (show NGEF Proteins)/ROCK2 (show ROCK2 Proteins) pathway after subarachnoid hemorrhage.

  4. Our studies show that forward signaling through the EphA4 tyrosine kinase receptor (show KDR Proteins), mediated by ephrins expressed by subpopulations of neuroblasts and astrocytes, is required for compact, directional organization of neuroblasts and astrocytes within the pathway and efficient transit of neuroblasts through the anterior forebrain to the olfactory bulb.

  5. Findings suggest a putative novel mechanism for desipramine to modulate long-term potentiation through the regulation of the ephrinA3/EphA4 signaling pathway

  6. Delineation of the specific mutation in EphA4 in this strain is important for further functional studies, such as protein-protein interactions, immunostaining and gene compensatory studies, investigating the mechanism underlying the effects of altered function of Eph (show EPHA1 Proteins) family of receptor tyrosine kinases on phenotype.

  7. the results of the present study demonstrated that angiogenesis occurs, and that the molecules EphA4 and ephrin-A5 (show EFNA5 Proteins) are expressed in the hippocampal CA1 (show CA1 Proteins) and CA3 (show CA3 Proteins) areas throughout epileptogenesis. PECAM-1 (show PECAM1 Proteins) may detect epileptic microvessel patterns in the hippocampi of mice and EphA4 may contribute to the microvessel plasticity via the ephrin-A5 (show EFNA5 Proteins) signaling pathway.

  8. results suggest that EphA4 is involved in circadian sleep regulation

  9. The findings of this study revealed the behavioral and circuit-level impact of conditional EphA4 mutation in a transcriptionally defined spinal interneuron subpopulation.

  10. Data show the effects of genetic loss of ephrin-A5, Eph receptors EphA4, and EphA7 on the development of medulloblastoma tumors in the smoothened (Smo) transgenic mouse model.

Human EPH Receptor A4 (EPHA4) interaction partners

  1. Molecular interactions of EphA4, growth hormone receptor (show GHR Proteins), Jak2 (show JAK2 Proteins), and STAT5B (show STAT5B Proteins) have been described.

  2. Findings demonstrated that mutant alpha2-chimaerin and EphA4 have different genetic interactions in distinct motor neuron pools: abducens neurons use bidirectional ephrin signaling via mutant alpha2-chimaerin to direct growth, while cervical spinal neurons use only ephrin forward signaling

  3. Reduced EphA4 expression is associated with EBV-associated B lymphoma.

  4. No difference was found in the expression of EPHA4 in morphologically normal glands, HGPIN, or prostatic cancer.

  5. we supposed that EphA4 interacted with CDK5 (show CDK5 Proteins) and promoted its expression which in turn enhanced p-AKT (show AKT1 Proteins) expression and promoted cell adhesion-mediated drug resistance in multiple myeloma.

  6. EphA4 was reduced in breast carcinoma, which is associated with high grade, advanced TNM (show ODZ1 Proteins) stage, lymph node metastasis, and poor outcome of patients

  7. Host EphA4 expression regulates cancer development mainly via EphA4-mediated IGF1 (show IGF1 Proteins) synthesis signal.

  8. EPHA4 is overexpressed but not functionally active in Sezary syndrome.

  9. The signaling complex appears to integrate the input from FGFR (show FGFR2 Proteins) and EphA4, and release the output signal through FRS2alpha (show FRS2 Proteins).

  10. EphA4 induced accumulation of amyloid precursor protein (show APP Proteins) through a Lyn (show LYN Proteins)-mediated pathway.

Pig (Porcine) EPH Receptor A4 (EPHA4) interaction partners

  1. expression of Eph (show EPHA1 Proteins) A1, A2, A4, and A7 was strongly detected in endometrial epithelial cells during early pregnancy.

  2. The EphA4 gene is significantly associated with litter size in pigs.

EPH Receptor A4 (EPHA4) Protein Profile

Protein Summary

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.

Alternative names and synonyms associated with EPH Receptor A4 (EPHA4)

  • EPH receptor A4 (EPHA4)
  • ephrin receptor epsilon (ephe)
  • EPH receptor A4 (epha4)
  • Eph receptor A4 (Epha4)
  • 2900005C20Rik protein
  • AI385584 protein
  • Cek8 protein
  • Ci-Eph1 protein
  • EPHA4 protein
  • ephe protein
  • HEK8 protein
  • rb protein
  • RGD1560587 protein
  • rtk1 protein
  • SEK protein
  • Sek1 protein
  • tyr01 protein
  • TYRO1 protein

Protein level used designations for EPH Receptor A4 Proteins (EPHA4)

ephrin receptor epsilon , EPH receptor A4 , ephrin receptor EphA4 , ephrin type-A receptor 4 , ephrin receptor EphA4-like , ephrin type-A receptor 4-like , tyrosine-protein kinase receptor MPK-3 , tyrosine-protein kinase receptor SEK-1 , EK8 , EPH-like kinase 8 , TYRO1 protein tyrosine kinase , receptor protein-tyrosine kinase HEK8 , tyrosine-protein kinase TYRO1 , tyrosine-protein kinase receptor SEK , Cek8

100060325 Equus caballus
445710 Ciona intestinalis
470660 Pan troglodytes
520192 Bos taurus
704857 Macaca mulatta
100216124 Xenopus (Silurana) tropicalis
100357064 Oryctolagus cuniculus
100405736 Callithrix jacchus
100458982 Pongo abelii
100469117 Ailuropoda melanoleuca
13838 Mus musculus
2043 Homo sapiens
395559 Gallus gallus
478925 Canis lupus familiaris
100188979 Sus scrofa
316539 Rattus norvegicus
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