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anti-Human FGF21 Antibodies:
anti-Mouse (Murine) FGF21 Antibodies:
anti-Rat (Rattus) FGF21 Antibodies:
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Human Monoclonal FGF21 Primary Antibody for IHC (p), ELISA - ABIN395569
Kaess, Barnes, Stark, Charchar, Waterworth, Song, Wang, Vollenweider, Waeber, Mooser, Zukowska-Szczechowska, Samani, Hengstenberg, Tomaszewski: FGF21 signalling pathway and metabolic traits - genetic association analysis. in European journal of human genetics : EJHG 2010
Show all 5 references for ABIN395569
Cow (Bovine) Polyclonal FGF21 Primary Antibody for IHC, WB - ABIN2786170
Chen, Li, Yang, Li, Qi, Zhu, Tang, Liu, Boden: Circulating FGF-21 levels in normal subjects and in newly diagnose patients with Type 2 diabetes mellitus. in Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2008
Human Polyclonal FGF21 Primary Antibody for ELISA, WB - ABIN238569
Inagaki, Dutchak, Zhao, Ding, Gautron, Parameswara, Li, Goetz, Mohammadi, Esser, Elmquist, Gerard, Burgess, Hammer, Mangelsdorf, Kliewer: Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21. in Cell metabolism 2007
FGF21-PXR (show NR1I2 Antibodies) signaling pathway may be involved in decreased hepatic CYP3A4 (show CYP3A4 Antibodies) metabolic activity in Nonalcoholic fatty liver disease.
data show that AHR (show AHR Antibodies) contributes to hepatic energy homeostasis, partly through the regulation of FGF21 expression and signaling.
Chronic stimulation of PPARalpha (show PPARA Antibodies) may suppress the autophagy capacity in the liver as a result of reduced content of a number of autophagy-associated proteins independent of FGF21.
Study compared the diagnostic utility of GDF-15 (show GDF15 Antibodies) with FGF-21 in an adult mitochondrial disease cohort. GDF-15 (show GDF15 Antibodies) outperforms FGF-21 as an indicator of mitochondrial diseases. GDF-15 (show GDF15 Antibodies) is generally indicative of inherited mitochondrial disease regardless of clinical phenotype, whereas FGF-21 seems to be more indicative of mitochondrial disease when muscle manifestations are present
The results suggest that increased circulating CK-18 (show KRT18 Antibodies) and FGF-21 are associated with Nonalcoholic Fatty Liver Disease and may be used for initial assessment, but not enough
Plasma FGF21 concentrations are increased in prediabetic first-degree relatives of patients with type 2 diabetes mellitus and that there is a significant association between FGF21 and obesity and insulin (show INS Antibodies) sensitivity.
This review will give a comprehensive understanding of the underlying role of FGF21 and its possible interaction with other molecules in Diabetic nephropathy
FGF21 is a novel surrogate diagnostic biomarker in initial stages of T2 Diabetic retinopathy (particularly with FGF21 values above 135.5pg/mL).
Accumulation of adipose tissue in the RS is related with the visceral adipose amount, KIM-1 (show HAVCR1 Antibodies) and FGF-21 concentration increase in the blood serum.
The results showed that the FGF21 promoter contains three response elements for ATF4 (show ATF4 Antibodies), suggesting that FGF21 is a sensitive target of ATF4 (show ATF4 Antibodies).
RESULTS: The results showed that serum FGF-21 levels were significantly higher in both groups treated with a controlled-energy diet, while FGF-21 levels in both groups treated with moderate-energy diet were low.
liver-derived FGF21 regulates the use of lipid reserves during lactation via focal actions on liver and white adipose tissue.
this study shows that FGF21 exerts an anti-inflammatory effect mainly via enhancing Nrf2 (show NFE2L2 Antibodies)-mediated anti-oxidant capacity and suppressing NF-kappaB (show NFKB1 Antibodies) signaling pathway
FGF21 corrects multiple metabolic parameters on NAFLD (show TSC2 Antibodies) in vitro and in vivo by inducing autophagy.
these data reveal a previously unidentified role for FGF21 on bile acid metabolism and may be relevant to understand the effects of FGF21 analogs in clinical studies.
These results suggest for the first time that FF prevents the development of diabetic nephropathy via up-regulating FGF21 and stimulating PI3K/Akt (show AKT1 Antibodies)/GSK-3b/Fyn (show FYN Antibodies)-mediated activation of the Nrf2 (show NFE2L2 Antibodies) pathway.
The requirement of fibroblast growth factor 21 for the metabolic actions of hepatic cJun (show JUN Antibodies) NH2-terminal kinase provides a mechanism for metabolic regulation by the JNK (show MAPK8 Antibodies)-signaling pathway in the liver.
These findings establish Rev-erbalpha (show NR1D1 Antibodies) as a specific modulator of FGF21 signaling in adipose tissue.
the liver regulates carbohydrate intake through production of the hepatokine fibroblast growth factor 21 (FGF21), which markedly suppresses consumption of simple sugars, but not complex carbohydrates, proteins, or lipids.
FGF21 administration markedly reduces sweet and alcohol preference in mice and sweet preference in cynomolgus monkeys.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this growth factor has not yet been determined.
fibroblast growth factor 21