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Browse our anti-FGFR1 (FGFR1) Antibodies

Full name:
anti-Fibroblast Growth Factor Receptor 1 Antibodies (FGFR1)
On are 586 Fibroblast Growth Factor Receptor 1 (FGFR1) Antibodies from 29 different suppliers available. Additionally we are shipping FGFR1 Proteins (48) and FGFR1 Kits (40) and many more products for this protein. A total of 722 FGFR1 products are currently listed.
ach, AW208770, bFGF-R-1, BFGFR, cb231, CD331, cd333, CEK, cek2, CG7223, CT22273, CT39172, DFGF-R1, DFGF-R2, Dfr-1, Dfr1, DFR1/DFGF-R2, Dmel\\CG7223, DmHD-38, DPR3, dtk1, DTRK(FR1), Eask, EMS2, FGF-R2, FGFBR, fgfr, Fgfr-1, fgfr-3, fgfr1, FGFR2, FGFRI, FLG, FLG-1, Flt-2, FLT2, Fr1, HBGFR, HD-38, HH2, hsfgfr3ex, Hspy, Htl, HTL/FGFR1, i79, i100, i150, j372, jtk4, KAL2, N-SAM, OGD, sb:cb231, Tk1, x1fgfr, XFGFR-1, xfgfr1, XFGFRA2
list all antibodies Gene Name GeneID UniProt
FGFR1 2260 P11362
FGFR1 14182 P16092
FGFR1 79114 Q04589

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Top referenced anti-FGFR1 Antibodies

  1. Human Polyclonal FGFR1 Primary Antibody for EIA, IHC (p) - ABIN358128 : Ng, Boucher, Koh, Sastry, Chase, Lakshmipathy, Choong, Yang, Vemuri, Rao, Tanavde et al.: PDGF, TGF-beta, and FGF signaling is important for differentiation and growth of mesenchymal stem cells (MSCs): transcriptional profiling can identify markers and signaling pathways important in ... in Blood 2008 (PubMed)
    Show all 6 references for ABIN358128

  2. Human Polyclonal FGFR1 Primary Antibody for EIA, WB - ABIN4620445 : Jiao, Greendorfer, Zhang, Zinn, Diglio, Thompson: Alternatively spliced FGFR-1 isoform signaling differentially modulates endothelial cell responses to peroxynitrite. in Archives of biochemistry and biophysics 2003 (PubMed)
    Show all 5 references for ABIN4620445

  3. Human Polyclonal FGFR1 Primary Antibody for EIA, WB - ABIN4620447 : Fu, Abu-Khalil, Morrison, Geschwind, Kornblum: Expression patterns of epidermal growth factor receptor and fibroblast growth factor receptor 1 mRNA in fetal human brain. in The Journal of comparative neurology 2003 (PubMed)
    Show all 5 references for ABIN4620447

  4. Human Polyclonal FGFR1 Primary Antibody for EIA, WB - ABIN4620446 : Lundin, Rönnstrand, Cross, Hellberg, Lindahl, Claesson-Welsh: Differential tyrosine phosphorylation of fibroblast growth factor (FGF) receptor-1 and receptor proximal signal transduction in response to FGF-2 and heparin. in Experimental cell research 2003 (PubMed)
    Show all 5 references for ABIN4620446

  5. Human Polyclonal FGFR1 Primary Antibody for EIA - ABIN358279 : Hu, Fang, Dunham, Prada, Stachowiak, Stachowiak: 90-kDa ribosomal S6 kinase is a direct target for the nuclear fibroblast growth factor receptor 1 (FGFR1): role in FGFR1 signaling. in The Journal of biological chemistry 2004 (PubMed)
    Show all 5 references for ABIN358279

  6. Human Polyclonal FGFR1 Primary Antibody for EIA, WB - ABIN359853 : Kiselyov, Skladchikova, Hinsby, Jensen, Kulahin, Soroka, Pedersen, Tsetlin, Poulsen, Berezin, Bock: Structural basis for a direct interaction between FGFR1 and NCAM and evidence for a regulatory role of ATP. in Structure (London, England : 1993) 2003 (PubMed)
    Show all 5 references for ABIN359853

  7. Human Polyclonal FGFR1 Primary Antibody for EIA, WB - ABIN951300 : Turner, Pearson, Sharpe, Lambros, Geyer, Lopez-Garcia, Natrajan, Marchio, Iorns, Mackay, Gillett, Grigoriadis, Tutt, Reis-Filho, Ashworth: FGFR1 amplification drives endocrine therapy resistance and is a therapeutic target in breast cancer. in Cancer research 2010 (PubMed)
    Show all 4 references for ABIN951300

  8. Human Polyclonal FGFR1 Primary Antibody for DB - ABIN389709 : Ibrahimi, Zhang, Hrstka, Mohammadi, Linhardt: Kinetic model for FGF, FGFR, and proteoglycan signal transduction complex assembly. in Biochemistry 2004 (PubMed)
    Show all 2 references for ABIN389709

  9. Human Polyclonal FGFR1 Primary Antibody for IHC, ELISA - ABIN185351 : Torry, Mukherjea, Arroyo, Torry: Expression and function of placenta growth factor: implications for abnormal placentation. in Journal of the Society for Gynecologic Investigation 2003 (PubMed)

  10. Human Polyclonal FGFR1 Primary Antibody for IHC, ELISA - ABIN1532336 : Popovici, Zhang, Grégoire, Jonveaux, Lafage-Pochitaloff, Birnbaum, Pébusque: The t(6;8)(q27;p11) translocation in a stem cell myeloproliferative disorder fuses a novel gene, FOP, to fibroblast growth factor receptor 1. in Blood 1999 (PubMed)

More Antibodies against FGFR1 Interaction Partners

Xenopus laevis Fibroblast Growth Factor Receptor 1 (FGFR1) interaction partners

  1. These results suggest that bFGF (show FGF2 Antibodies) activation of neuronal FGFR1 generates filopodial processes in neurons that promote nerve-muscle interaction and facilitate NMJ establishment.

  2. in FGFR1 signalling JNK1 (show MAPK8 Antibodies) phosphorylation depends on ERK2 (show MAPK1 Antibodies)

Fruit Fly (Drosophila melanogaster) Fibroblast Growth Factor Receptor 1 (FGFR1) interaction partners

  1. identify two transcriptional regulators that function downstream of Heartless signaling in lymph gland progenitors, the ETS protein, Pointed, and the Friend-of-GATA protein, U-shaped, which are required for this Heartless-induced differentiation response

  2. We show that salivary gland posterior migration requires the activities of genes that position the visceral mesoderm precursors, such as heartless, thickveins, and tinman (show MSH2 Antibodies), but does not require a differentiated visceral mesoderm.

  3. the signal provided by the CAMs acts via the Heartless fibroblast growth factor receptor (FGFR) as outgrowth is reduced to basal levels in the presence of an FGFR (show FGFR2 Antibodies) inhibitor or if Heartless function is missing from the neurons.

Human Fibroblast Growth Factor Receptor 1 (FGFR1) interaction partners

  1. we identified heterozygous loss-of-function mutations of FGFR1 in four patients with HH-SHFM. Of note, this study indicates that loss of the promoter region around exon 1U underlies FGFR1-related disorders.

  2. A novel dominant negative FGFR1 mutation identified in the Kallman syndrome patient.

  3. High FGFR1 expression was significantly associated with the depth of invasion, lymph-node metastasis, pathological stage, and distant metastasis or recurrent disease in gastric cancer.

  4. The expression intensity of FGFR1 and VEGFR2 (show KDR Antibodies) was associated with MVD (show MVD Antibodies), and the expression of FGFR1 is one of the independent prognostic indicators for NSCLC.

  5. FGFR1 amplification is associated with advanced squamous non-small cell lung cancer.

  6. Moreover, mechanistic study reveals that PD166866 induces autophagy through repressing Akt (show AKT1 Antibodies)/mTOR (show FRAP1 Antibodies) signaling pathway. Together, the present study provides new insights into the molecular mechanisms underlying the anti-tumor activities of FGFR (show FGFR2 Antibodies) antagonists, and may further assist the FGFRs-based drug discovery.

  7. activation of AurA (show AURKA Antibodies) kinase through FGF1 (show FGF1 Antibodies)/FGFR (show FGFR2 Antibodies) signaling axis sustains the stem cell characteristics of glioblastoma cells.

  8. FGFR1 amplification and MYC (show MYC Antibodies) expression have prognostic implications in resected esophageal squamous cell carcinomas with respect to adjuvant therapy.

  9. In this report we described the first successful development of a model of human ZMYM2 (show ZMYM2 Antibodies)-FGFR1 driven AML (show RUNX1 Antibodies) in immunocompromised mice, which shows an etiology consistent with the development of the primary human disease.

  10. FGFR1 translocation was present in two out of four cases of phosphaturic mesenchymal tumor

Mouse (Murine) Fibroblast Growth Factor Receptor 1 (FGFR1) interaction partners

  1. The study supports a pro-adipogenic role for betaKlotho (show KLB Antibodies) in skeletal muscle fibro/adipogenesis and calls for further research on involvement of the FGF-FGFR (show FGFR2 Antibodies)-betaKlotho (show KLB Antibodies) axis in the fibro/adipogenic infiltration associated with functional deterioration of skeletal muscle in aging and muscular dystrophy.

  2. These new findings reveal that the FGF21-betaKlotho-FGFR1 signaling axis plays roles in maintaining phospholipid homeostasis and the dynamic functions of the lipid droplet, whereas protecting against ER stress, and suggest a potential link of phospholipid biosynthesis, lipid droplet dynamics, ER stress, and energy homeostasis in adipose tissue coordinated by this signaling axis.

  3. Data suggest that Fgf1 (show FGF1 Antibodies)-mediated signaling represents an important signaling cascade related to adipogenesis and visceral adiposity; expression of Fgf1 (fibroblast growth factor 1 (show FGF1 Antibodies)) and Fgfr1 (fibroblast growth factor receptor 1) is up-regulated in adipose tissue of obese mice (both obese mice due to high-fat diet and obese mice due to genetic deletion of leptin (show LEP Antibodies)).

  4. FGFR1OP2 (show FGFR1OP2 Antibodies)-FGFR1 fusion in hematopoietic stem cells induced myeloid leukemia (show BCL11A Antibodies) and T-cell lymphoma in a mouse model.

  5. MiR (show MLXIP Antibodies)-214 was up-regulated in mesenchymal stem cells of osteoporotic mice and down-regulated during osteoblast differentiation of mesenchymal stem cells. FGFR1 is a direct target of miR (show MLXIP Antibodies)-214.

  6. demonstrated that Id1 (show ID1 Antibodies) and E2-2 (show TCF4 Antibodies) are critical regulators of EPCs function in vitro. Id1 (show ID1 Antibodies) interacts with E2-2 (show TCF4 Antibodies) and relieves the E2-2 (show TCF4 Antibodies)-mediated repression of FGFR1 and VEGFR2 (show KDR Antibodies) expression to modulate EPCs functions

  7. FGF receptor 1-mediated anosmin-1 (show KAL1 Antibodies) activity plays a crucial role in the continuous remodelling of the adult olfactory bulb.

  8. Fgfr1 and Fgfr2 (show FGFR2 Antibodies) in the palatal and mandibular mesenchyme have roles in regulating shelf medial wall protrusion and growth of the mandible to coordinate the craniofacial tissue movements that are required for palatal shelf elevation

  9. Data suggest that signal transduction via Fgf23 (show FGF23 Antibodies)/Fgfr1 and calcitriol/calcitriol receptor have opposite roles in innate immunity; Fgf23 (show FGF23 Antibodies) suppresses arginase-1 (show ARG1 Antibodies) expression in macrophages; calcitriol stimulates arginase-1 (show ARG1 Antibodies) expression in macrophages.

  10. FGFR1 has dual functions to directly regulate proximal and distal tubule phosphate and calcium reabsorption, indicating a physiological role of FGFR1 signaling in both phosphate and calcium homeostasis.

Cow (Bovine) Fibroblast Growth Factor Receptor 1 (FGFR1) interaction partners

  1. Alterations in the expression of VEGF-A (show VEGFA Antibodies) and bFGF (show FGF2 Antibodies) systems suggest that angiogenic factors are involved in abnormal placental development in cloned gestations, contributing to impaired fetal development and poor survival rates.

Pig (Porcine) Fibroblast Growth Factor Receptor 1 (FGFR1) interaction partners

  1. mRNA and protein expression of FGFR-1, FGFR-2 (show FGFR2 Antibodies) in the porcine umbilical cord during pregnancy.

Zebrafish Fibroblast Growth Factor Receptor 1 (FGFR1) interaction partners

  1. we show that minimal amounts of Fgfr1a or Fgfr2 are required to initiate a regulatory cascade in pharyngeal endoderm reducing expression of fsta, thereby allowing correct BMP signaling to the maturing chondrocytes of the head cartilage.

  2. Data indicate that fgf20a, fgf24, FGF receptor (show FGFR2 Antibodies) fgfr1 are expressed in normal and regenerating barbel tissue.

  3. Shroom3 (show SHROOM3 Antibodies) is required downstream of FGF signalling to mediate proneuromast assembly in zebrafish.

  4. fgfr (show FGFR2 Antibodies) expression is directly or indirectly regulated by FGF signaling during epiboly and at the end of somitogenesis.

  5. we describe cloning and expression analysis of the zebrafish fibroblast growth factor receptor 1 ( fgfr1).

  6. knock-down of Fgfr1, but not muscle segment homeobox B, affected the blastemal expression of msxc, suggesting this technique can be used to determine epistasis in genetic pathways affecting regeneration

  7. Bmp and Fgf signaling are essential for liver specification in zebrafish.

  8. The analysis of receptor-ligand interactions between D. rerio fgf8 (show FGF8 Antibodies) and its receptors, fgfr1 and fgfr4 (show FGFR4 Antibodies), using combined spectroscopy methods are reported.

FGFR1 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described\; however, not all variants have been fully characterized.

Alternative names and synonyms associated with FGFR1

  • fibroblast growth factor receptor (FGFR) antibody
  • fibroblast growth factor receptor (fgfr) antibody
  • fibroblast growth factor receptor 1 (fgfr1-a) antibody
  • basic fibroblast growth factor receptor 1 (CpipJ_CPIJ005849) antibody
  • heartless (htl) antibody
  • fibroblast growth factor receptor 1 (fgfr1) antibody
  • fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) (fgfr3) antibody
  • fibroblast growth factor receptor 1 (FGFR1) antibody
  • fibroblast growth factor receptor 1 (Fgfr1) antibody
  • Fibroblast growth factor receptor 1 (Fgfr1) antibody
  • fibroblast growth factor receptor 1 (fgfr1-b) antibody
  • fibroblast growth factor receptor 1a (fgfr1a) antibody
  • ach antibody
  • AW208770 antibody
  • bFGF-R-1 antibody
  • BFGFR antibody
  • cb231 antibody
  • CD331 antibody
  • cd333 antibody
  • CEK antibody
  • cek2 antibody
  • CG7223 antibody
  • CT22273 antibody
  • CT39172 antibody
  • DFGF-R1 antibody
  • DFGF-R2 antibody
  • Dfr-1 antibody
  • Dfr1 antibody
  • DFR1/DFGF-R2 antibody
  • Dmel\\CG7223 antibody
  • DmHD-38 antibody
  • DPR3 antibody
  • dtk1 antibody
  • DTRK(FR1) antibody
  • Eask antibody
  • EMS2 antibody
  • FGF-R2 antibody
  • FGFBR antibody
  • fgfr antibody
  • Fgfr-1 antibody
  • fgfr-3 antibody
  • fgfr1 antibody
  • FGFR2 antibody
  • FGFRI antibody
  • FLG antibody
  • FLG-1 antibody
  • Flt-2 antibody
  • FLT2 antibody
  • Fr1 antibody
  • HBGFR antibody
  • HD-38 antibody
  • HH2 antibody
  • hsfgfr3ex antibody
  • Hspy antibody
  • Htl antibody
  • HTL/FGFR1 antibody
  • i79 antibody
  • i100 antibody
  • i150 antibody
  • j372 antibody
  • jtk4 antibody
  • KAL2 antibody
  • N-SAM antibody
  • OGD antibody
  • sb:cb231 antibody
  • Tk1 antibody
  • x1fgfr antibody
  • XFGFR-1 antibody
  • xfgfr1 antibody
  • XFGFRA2 antibody

Protein level used designations for FGFR1

fibroblast growth factor receptor , FGFR-1 , fibroblast growth factor receptor-1 , basic fibroblast growth factor receptor 1 , CG7223-PA , CG7223-PB , CG7223-PC , FGF receptor , fibroblast growth factor receptor 1 , htl-PA , htl-PB , htl-PC , fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) , ibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) , basic fibroblast growth factor receptor 1-like , FGFR1/PLAG1 fusion , FMS-like tyrosine kinase 2 , fms-related tyrosine kinase 2 , heparin-binding growth factor receptor , hydroxyaryl-protein kinase , proto-oncogene c-Fgr , MFR , bFGF-R-1 , c-fgr , FGF receptor-1 , bFGF-R , cek1 protein , tyrosine kinase receptor CEK1 , FGFR-1-A , bFGF-R-1-A , basic fibroblast growth factor receptor 1-A , fibroblast growth factor receptor 1-A

373310 Strongylocentrotus purpuratus
445706 Ciona intestinalis
394418 Xenopus laevis
6037802 Culex quinquefasciatus
42160 Drosophila melanogaster
548648 Xenopus (Silurana) tropicalis
779370 Xenopus laevis
100390192 Callithrix jacchus
2260 Homo sapiens
14182 Mus musculus
79114 Rattus norvegicus
475582 Canis lupus familiaris
281768 Bos taurus
464122 Pan troglodytes
100057614 Equus caballus
100153248 Sus scrofa
396516 Gallus gallus
100731156 Cavia porcellus
399444 Xenopus laevis
100351861 Oryctolagus cuniculus
30705 Danio rerio
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