Browse our anti-FGFR4 (FGFR4) Antibodies

Full name:
anti-Fibroblast Growth Factor Receptor 4 Antibodies (FGFR4)
On are 211 Fibroblast Growth Factor Receptor 4 (FGFR4) Antibodies from 31 different suppliers available. Additionally we are shipping FGFR4 Proteins (49) and FGFR4 Kits (30) and many more products for this protein. A total of 309 FGFR4 products are currently listed.
CD334, etID309818.21, Fgfr-4, fgfr-4c, fgfr4, JTK2, TKF, wu:fc13h10, XFGFR-4, XFGFR-4a, xfgfr4, zgc:111935
list all antibodies Gene Name GeneID UniProt
FGFR4 2264 P22455
FGFR4 14186 Q03142
FGFR4 25114 Q498D6

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anti-Human FGFR4 Antibodies:

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anti-Rat (Rattus) FGFR4 Antibodies:

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Top referenced anti-FGFR4 Antibodies

  1. Human Polyclonal FGFR4 Primary Antibody for EIA, WB - ABIN359860 : Jézéquel, Campion, Joalland, Millour, Dravet, Classe, Delecroix, Deporte, Fumoleau, Ricolleau: G388R mutation of the FGFR4 gene is not relevant to breast cancer prognosis. in British journal of cancer 2004 (PubMed)
    Show all 5 references for 359860

  2. Human Polyclonal FGFR4 Primary Antibody for WB - ABIN871709 : Takaishi, Sawada, Morita, Seno, Fukuzawa, Chiba: Identification of a novel alternative splicing of human FGF receptor 4: soluble-form splice variant expressed in human gastrointestinal epithelial cells. in Biochemical and biophysical research communications 2000 (PubMed)
    Show all 2 references for 871709

  3. Human Monoclonal FGFR4 Primary Antibody for ICC, ELISA - ABIN969140 : Streit, Mestel, Schmidt, Ullrich, Berking: FGFR4 Arg388 allele correlates with tumour thickness and FGFR4 protein expression with survival of melanoma patients. in British journal of cancer 2006 (PubMed)
    Show all 2 references for 969140

  4. Human Monoclonal FGFR4 Primary Antibody for IHC, ELISA - ABIN969139 : Ezzat, Zheng, Winer, Asa: Targeting N-cadherin through fibroblast growth factor receptor-4: distinct pathogenetic and therapeutic implications. in Molecular endocrinology (Baltimore, Md.) 2006 (PubMed)
    Show all 2 references for 969139

  5. Mouse (Murine) Polyclonal FGFR4 Primary Antibody for ELISA - ABIN2000537 : Xie, Holcomb, Deuel, Dowd, Huang, Vagts, Foster, Liang, Brush, Gu, Hillan, Goddard, Gurney: FGF-19, a novel fibroblast growth factor with unique specificity for FGFR4. in Cytokine 1999 (PubMed)

More Antibodies against FGFR4 Interaction Partners

Cow (Bovine) Fibroblast Growth Factor Receptor 4 (FGFR4) interaction partners

  1. Alterations in the expression of VEGF-A (show VEGFA Antibodies) and bFGF (show FGF2 Antibodies) systems suggest that angiogenic factors are involved in abnormal placental development in cloned gestations, contributing to impaired fetal development and poor survival rates.

Human Fibroblast Growth Factor Receptor 4 (FGFR4) interaction partners

  1. Enhanced myocardial expression of FGFR4 is associated with left ventricular hypertrophy in chronic kidney disease.

  2. These observations suggest a crucial role for cancer-associated fibroblasts and fibroblast growth factor-1 (show FGF1 Antibodies)/fibroblast growth factor receptor 4 signaling in the progression of ovarian cancer. the expression level of Snail1 (show SNAI1 Antibodies) and MMP3 (show MMP3 Antibodies) was reduced, while the expression level of E-cadherin (show CDH1 Antibodies) increased

  3. High FGFR4 expression was significantly associated with the depth of invasion, lymph-node metastasis, pathological stage, and distant metastasis or recurrent disease in gastric cancer.

  4. This study showed that Gly388Arg FGFR4 Polymorphism Is Not Predictive of Everolimus Efficacy in Well-Differentiated Digestive Neuroendocrine Tumors.

  5. Data suggest that knockdown of fibroblast growth factor receptor 4 (FGFR4) expression might prevent the growth of astric cancer (GC) in vivo.

  6. FGFR4 is overexpressed in oral squamous cell carcinoma (OSCC) and oropharyngeal squamous cell carcinoma (OPSCC) in the absence of gene amplification, and may serve as a potential predictive marker for FGFR4-directed targeted therapy in OSCC and OPSCC.

  7. analysis of FGFR3 (show FGFR3 Antibodies) and FGFR4 gene polymorphisms in breast cancer in Chinese women of Heilongjiang province reveals that SNPs rs1966265 and rs351855 in FGFR4 , but not rs2234909 and rs3135848 in FGFR3 (show FGFR3 Antibodies) are associated with breast cancer

  8. Study shows that FGF19 (show FGF19 Antibodies) can be secreted and promotes ovarian cancer progression such as proliferation and invasion by activating FGFR4.

  9. The FGFR4 single-nucleotide polymorphism rs376618 had borderline significant differences in Patients With Primary Bile Acid Diarrhea.

  10. Our study provides the first evidence of a role for FGFR4 in neuroblastoma (show ARHGEF16 Antibodies)

Mouse (Murine) Fibroblast Growth Factor Receptor 4 (FGFR4) interaction partners

  1. Blocking FGFR4 inhibits cardiac calcineurin (show PPP3CA Antibodies)/NFAT (show NFATC1 Antibodies) signaling and attenuates the development of LVH and cardiac fibrosis in a well-established animal model of CKD without significantly altering kidney function, blood pressure, or FGF23 (show FGF23 Antibodies) levels.

  2. The FGFR4 transmembrane polymorphic variants can modulate cellular growth and sensitivity to glucocorticoid hormone negative feedback.

  3. FGFR4 deficiency in mice leads to improvement in glucose metabolism, insulin (show INS Antibodies) sensitivity, and reduction in body weight under high fat conditions.

  4. The FGFR4-R388 allele yields a receptor variant that preferentially promotes STAT3 (show STAT3 Antibodies)/5 signaling.

  5. study shows FGFR4 is specifically up regulated by PAX3 (show PAX3 Antibodies)-FOXO1 (show FOXO1 Antibodies); however this FGFR4 over expression does not contribute to PAX3 (show PAX3 Antibodies)-FOXO1 (show FOXO1 Antibodies) tumorigenic phenotypes in primary skeletal muscle myoblasts

  6. findings suggest a modulatory role for FGFR4 in the development and progression of hepatocellular carcinoma and that FGFR4 may be an important and novel therapeutic target in treating this disease

  7. Differential specificity of endocrine FGF19 (show FGF19 Antibodies) and FGF21 (show FGF21 Antibodies) to FGFR1 (show FGFR1 Antibodies) and FGFR4 in complex with KLB (show KLB Antibodies).

  8. FGFR3 (show FGFR3 Antibodies) and 4 are the receptors that regulate serum 1,25(OH)(2)Vitamin D(3) levels in response to FGF23 (show FGF23 Antibodies).

  9. FGFR4 activation mediates the induction of hepatocyte proliferation and the suppression of bile acid biosynthesis by FGF19 (show FGF19 Antibodies).

  10. These studies suggest that FGFR1 (show FGFR1 Antibodies), FGFR3 (show FGFR3 Antibodies), and FGFR4 act in concert to mediate FGF23 (show FGF23 Antibodies) effects on the kidney and that loss of FGFR (show FGFR2 Antibodies) function leads to feedback stimulation of Fgf23 (show FGF23 Antibodies) expression in bone

Zebrafish Fibroblast Growth Factor Receptor 4 (FGFR4) interaction partners

  1. Fgfr4 mediates a signal-transduction pathway between Wnt16 (show WNT16 Antibodies) and Dlc, but not Dld, to regulate haematopoietic stem cells specification.

  2. The analysis of receptor-ligand interactions between D. rerio fgf8 (show FGF8 Antibodies) and its receptors, fgfr1 (show FGFR1 Antibodies) and fgfr4, using combined spectroscopy methods are reported.

FGFR4 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. The genomic organization of this gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms, as indicated for members 1-3. This particular family member preferentially binds acidic fibroblast growth factor and, although its specific function is unknown, it is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis.

Alternative names and synonyms associated with FGFR4

  • fibroblast growth factor receptor 4 (FGFR4) antibody
  • fibroblast growth factor receptor 4 (fgfr4) antibody
  • fibroblast growth factor receptor 4 (Fgfr4) antibody
  • fibroblast growth factor receptor 4 (fgfr4-b) antibody
  • CD334 antibody
  • etID309818.21 antibody
  • Fgfr-4 antibody
  • fgfr-4c antibody
  • fgfr4 antibody
  • JTK2 antibody
  • TKF antibody
  • wu:fc13h10 antibody
  • XFGFR-4 antibody
  • XFGFR-4a antibody
  • xfgfr4 antibody
  • zgc:111935 antibody

Protein level used designations for FGFR4

fibroblast growth factor receptor 4 , FGF receptor 4 , FGFR-4 , hydroxyaryl-protein kinase , protein-tyrosine kinase , tyrosine kinase related to fibroblast growth factor receptor , tyrosylprotein kinase , CTLA-2-beta protein , fibroblast growth factor receptor 4 16 minus form , protein-tyrosine kinase receptor MPK-11 , fibroblast growth factor receptor FREK , fibroblast growth factor receptor-like embryonic kinase , fibroblast growth factor receptor 4c

317696 Bos taurus
462301 Pan troglodytes
489095 Canis lupus familiaris
549077 Xenopus (Silurana) tropicalis
698494 Macaca mulatta
100477678 Ailuropoda melanoleuca
100582351 Nomascus leucogenys
2264 Homo sapiens
14186 Mus musculus
25114 Rattus norvegicus
100127133 Sus scrofa
395603 Gallus gallus
100355275 Oryctolagus cuniculus
100733523 Cavia porcellus
100000160 Danio rerio
398181 Xenopus laevis
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