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anti-Mouse (Murine) Galectin 3 Antibodies:
anti-Human Galectin 3 Antibodies:
anti-Rat (Rattus) Galectin 3 Antibodies:
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Human Monoclonal Galectin 3 Primary Antibody for IHC (f), ICS - ABIN2689513
Cherayil, Weiner, Pillai: The Mac-2 antigen is a galactose-specific lectin that binds IgE. in The Journal of experimental medicine 1990
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Human Polyclonal Galectin 3 Primary Antibody for CyTOF, FACS - ABIN4899436
Thijssen, Hulsmans, Griffioen: The galectin profile of the endothelium: altered expression and localization in activated and tumor endothelial cells. in The American journal of pathology 2008
Show all 3 Pubmed References
Human Monoclonal Galectin 3 Primary Antibody for Func, IA - ABIN2192045
Liu, Hsu, Zuberi, Hill, Shenhav, Kuwabara, Chen: Modulation of functional properties of galectin-3 by monoclonal antibodies binding to the non-lectin domains. in Biochemistry 1996
Show all 3 Pubmed References
Human Monoclonal Galectin 3 Primary Antibody for ELISA, FACS - ABIN152697
Staels, Rubenstrunk, Noel, Rigou, Delataille, Millatt, Baron, Lucas, Tailleux, Hum, Ratziu, Cariou, Hanf: Hepatoprotective effects of the dual peroxisome proliferator-activated receptor alpha/delta agonist, GFT505, in rodent models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. in Hepatology (Baltimore, Md.) 2013
Show all 2 Pubmed References
Human Polyclonal Galectin 3 Primary Antibody for IF (p), IHC (p) - ABIN672321
Lee, Bae, Choi, Park, Chun: Molecular cloning and expression analysis of pig CD7. in Veterinary research communications 2014
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Human Polyclonal Galectin 3 Primary Antibody for IHC (p), WB - ABIN657647
Salomonsson, Carlsson, Osla, Hendus-Altenburger, Kahl-Knutson, Oberg, Sundin, Nilsson, Nordberg-Karlsson, Nilsson, Karlsson, Rini, Leffler: Mutational tuning of galectin-3 specificity and biological function. in The Journal of biological chemistry 2010
Show all 4 Pubmed References
Mouse (Murine) Monoclonal Galectin 3 Primary Antibody for EIA, FACS - ABIN114277
Knisley, Weitlauf: Compartmentalized reactivity of M3/38 (anti-Mac-2) and M3/84 (anti-Mac-3) in the uterus of pregnant mice. in Journal of reproduction and fertility 1993
Show all 12 Pubmed References
Human Polyclonal Galectin 3 Primary Antibody for ELISA, WB - ABIN2473746
Dumic, Dabelic, Flögel: Galectin-3: an open-ended story. in Biochimica et biophysica acta 2006
Human Polyclonal Galectin 3 Primary Antibody for ELISA (Detection), FACS - ABIN4899434
Sioud, Mobergslien, Boudabous, Fløisand: Mesenchymal stem cell-mediated T cell suppression occurs through secreted galectins. in International journal of oncology 2010
Mouse (Murine) Monoclonal Galectin 3 Primary Antibody for FACS - ABIN4896110
Ansa-Addo, Lange, Stratton, Antwi-Baffour, Cestari, Ramirez, McCrossan, Inal: Human plasma membrane-derived vesicles halt proliferation and induce differentiation of THP-1 acute monocytic leukemia cells. in Journal of immunology (Baltimore, Md. : 1950) 2010
Mutational tuning of galectin-3 specificity and biological function.
Data suggest that different patterns of Pkd1 (show PKD1 Antibodies)-deficiency can lead to cardiac dysfunction and that galectin-3 has a role in intensifying this phenotype and limiting survival, effects potentially applicable to human autosomal dominant polycystic kidney disease.
This study reveals a uniquely regulated inflammatory response in the SVZ and shows that Gal-3 participates in remyelination in the cuprizone model.
Data demonstrated that the absence of host galectin-3 drastically affected the tumor biology favoring the metastatic spreading of 4T1 cells to inguinal lymph nodes and bone marrow colonization.
study demonstrated that endogenous Gal-3 is specifically involved in leukocyte slow rolling
Gal-3 influences remyelination by mechanisms involving the tuning of microglial cells, modulation of MMP activity, and changes in myelin architecture.
These data indicate a role for endogenous Gal-3 in neutrophil clearance during acute inflammation.
Our results suggest that endogenous galectin-3 regulates Notch (show NOTCH1 Antibodies) signaling activation in bone marrow-derived dendritic cells and influences polarization of T helper responses
Results suggest that prion protein PrPC (show PRNP Antibodies) combined with galectin-3 and -6 can act as a receptor for murine leukemia virus (MuLV).
This study indicates that the ANG II (show AGT Antibodies) effects are, in part, mediated or triggered by Gal-3 together with the related intercellular signaling (ICAM-1 (show ICAM1 Antibodies) and IL-6 (show IL6 Antibodies)), leading to cardiac inflammation and fibrosis.
Regulation of complement 5a receptor (C5aR (show C5AR1 Antibodies))-induced neutrophil chemotaxis via IgG1 immune complexes (ICs (show DNAI1 Antibodies)) depends on galectin-3.
We measured the effect of recombinant Gal-3 added exogenously on the lateral mobility of the alpha5b1 integrin on HeLa cells. Using single-particle tracking (SPT (show AGXT Antibodies)) we detected increased lateral mobility of the integrin in the presence of Gal-3, while its truncated C-terminal domain (Gal (show GAL Antibodies)-3C) showed only minor reductions in lateral mobility.
Data suggest that galectin-3 and heterogeneous ribonucleoprotein particle component hnRNPA2B1 (show HNRNPA2B1 Antibodies) interact as members of the early splicing machinery.
Increased Gal-3 reflects both increased neurohumoral activity and reduced glomerular filtration rate, but not myocardial function in patients with systolic heart failure.
Cell surface Gal3 expression identifies a subset ofcancer stem cells in gastrointestinal cancers with high levels of stem cell characteristics, including chemoresistance.
Galectin-3 and fibulin-1 (show FBLN1 Antibodies) levels are elevated in heart failure patients with impaired glucose metabolism. Reduced LV contractile reserve among HF patients with DM does not to have an independent impact on plasma Gal-3 and fibulin-1 (show FBLN1 Antibodies) levels.
Galectin-3 may serve as a useful biomarker for evaluating the severity and outcomes in heart failure and in patients undergoing left ventricular assist device implantation.
High galectin 3 expression is associated with colorectal cancer progression.
a novel role of Gal3 as an initiator of inflammatory signaling in autoimmune cholangitis, mediating the activation of NOD-like receptor family, pyrin domain containing 3 inflammasome and inducing IL-17 (show IL17A Antibodies) proinflammatory cascades
Galectin-3 levels and cystatin-C (show CST3 Antibodies) levels are independent predictors of 26-month mortality in patients with chronic heart failure
The current study supports the tumor suppression role of galectin-3 in endometrial carcinoma
Demonstrate that galectin-3 plays a critical role in hensin (show DMBT1 Antibodies) ECM (show MMRN1 Antibodies) assembly by oligomerizing secreted monomeric hensin (show DMBT1 Antibodies).
The overall findings suggest that the secreted galectin-3 stimulated by PGF (show PGF Antibodies) plays a role in structural luteolysis by binding to beta 1 integrin.
The relative abundance of PIBF (show PIBF1 Antibodies), LGALS1 (show LGALS1 Antibodies), LGALS3 (show LGALS2 Antibodies), LGALS3BP (show LGALS3BP Antibodies), and LGALS9 (show LGALS9 Antibodies) mRNA would display a differential expression pattern in the endometrium.
This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.
lectin, galactoside-binding, soluble, 3
, galectin 3
, lectin, galactoside-binding, soluble, 2
, 35 kDa lectin
, CBP 35
, L-34 galactoside-binding lectin
, carbohydrate-binding protein 35
, galactose-specific lectin 3
, igE-binding protein
, laminin-binding protein
, lectin L-29
, mac-2 antigen
, IgE-binding protein
, MAC-2 antigen
, IgE binding protein
, lectin, galactose binding, soluble 3
, beta-galactosides-binding lectin
, lectin, galactoside-binding, soluble, 3 (galectin 3)
, 3 (galectin 3)