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Browse our HGF Proteins (HGF)

Full name:
Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) Proteins (HGF)
On are 72 Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) Proteins from 18 different suppliers available. Additionally we are shipping HGF Antibodies (239) and HGF Kits (96) and many more products for this protein. A total of 424 HGF products are currently listed.
AI838057, c-Met, C230052L06Rik, DFNB39, F-TCF, HGF, HGF/SF, HGFB, HGFR, HPTA, NK1, NK2, Par4, SF, SF/HGF
list all proteins Gene Name GeneID UniProt
HGF 15234 Q08048
HGF 24446 P17945
HGF 3082 P14210

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HGF Proteins (HGF) by Origin

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Top referenced HGF Proteins

  1. Human HGF Protein expressed in Insect Cells - ABIN2666489 : DAngelo, Bernasconi, Schäfer, Moyat, Michetti, Maillard, Velin: Macrophages promote epithelial repair through hepatocyte growth factor secretion. in Clinical and experimental immunology 2013 (PubMed)
    Show all 6 references for ABIN2666489

  2. Rat (Rattus) HGF Protein expressed in Human Cells - ABIN2009606 : Comoglio: Structure, biosynthesis and biochemical properties of the HGF receptor in normal and malignant cells. in EXS 1993 (PubMed)
    Show all 4 references for ABIN2009606

  3. Mouse (Murine) HGF Protein expressed in Human Cells - ABIN2007211 : Brown, Gydesen, Johannsen, Gade, Skibinski, Chakrabarti, Brun, Spillantini, Yancopoulou, Thusgaard, Sorensen, Fisher, Collinge: Frontotemporal dementia linked to chromosome 3. in Dementia and geriatric cognitive disorders 2004 (PubMed)
    Show all 3 references for ABIN2007211

  4. Dog (Canine) HGF Protein expressed in Human Cells - ABIN2008912 : Kemp, Mulloy, Gherardi: Signalling by HGF/SF and Met: the role of heparan sulphate co-receptors. in Biochemical Society transactions 2006 (PubMed)
    Show all 3 references for ABIN2008912

  5. Rat (Rattus) HGF Protein expressed in Escherichia coli (E. coli) - ABIN1047160 : Okajima, Miyazawa, Kitamura: Primary structure of rat hepatocyte growth factor and induction of its mRNA during liver regeneration following hepatic injury. in European journal of biochemistry / FEBS 1990 (PubMed)
    Show all 2 references for ABIN1047160

  6. Human HGF Protein expressed in Insect Cells - ABIN1589618 : Rezzola, Dal Monte, Belleri, Bugatti, Chiodelli, Corsini, Cammalleri, Cancarini, Morbidelli, Oreste, Bagnoli, Semeraro, Presta: Therapeutic Potential of Anti-Angiogenic Multitarget N,O-Sulfated E. Coli K5 Polysaccharide in Diabetic Retinopathy. in Diabetes 2015 (PubMed)
    Show all 2 references for ABIN1589618

More Proteins for HGF Interaction Partners

Mouse (Murine) Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) interaction partners

  1. The results suggest that PGRN (show GRN Proteins) may affect the differentiation of retinal precursor cells to photoreceptor cells through the HGF receptor signaling pathway.

  2. study demonstrates that co-activation of AKT (show AKT1 Proteins) and c-Met induces hepatocellular carcinoma development that depends on the mTORC1/FASN (show FASN Proteins) pathway.

  3. Exposure of macrophages to cyclooxygenase (COX-2) inhibitors RhoA (show RHOA Proteins) and LA-4 cells to antagonists of prostaglandin E2 (PGE2) receptor , PGD2 (show PTGDS Proteins) receptors or the hepatocyte growth factor (HGF) receptor c-Met (PHA (show LBR Proteins)-665752), reversed EMT (show ITK Proteins) inhibition by the conditioned medium

  4. Notch (show NOTCH1 Proteins) signaling plays an important role in regulation of interactions between TGF-beta (show TGFB1 Proteins) and HGF signaling pathways in proximal tubule epithelial cells

  5. inhibition of PPARgamma (show PPARG Proteins) activity reversed the expression of transforming growth factor-beta (TGF-beta), interleukin (IL)-10 (show IL10 Proteins), and hepatocyte growth factor (HGF).

  6. Molecular and functional studies revealed that ectopic Met expression in limb mesenchyme does not alter HGF expression patterns and levels, but impairs HGF bioavailability

  7. miR-206 suppressed c-Met expression in gastric cancer and could function as a potent tumor suppressor in c-Met overexpressing tumors.

  8. These findings suggest that HGF overexpression can provide a potential therapeutic avenue as a combination therapy with disease-modifying therapies in SBMA (show AR Proteins).

  9. Apoptosis of cardiomyocytic & neuronal cells released HGF & HGF-mediated migration of mesenchymal stem cells towards apoptotic targets. HMGB1 (show HMGB1 Proteins) was mainly released by necrotic cells& mediated recruitment of monocytes and immature dendritic cells

  10. Meg3 overexpression in insulinoma cells down-regulated the expression of the protooncogene c-met.

Human Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) interaction partners

  1. HGF efficiently ameliorates the vascular response to stent implantation, and has an important redeeming influence on the deleterious endothelial effects of drug-eluting stents.

  2. Plasma HGF is overexpressed in amyloid light-chain cardiac amyloidosis.

  3. Using cytokine array analysis, we were able to demonstrate that GSC1 cell growth is mediated through hepatocyte growth factor (HGF)/c-MET signaling pathway which is activated exclusively by HGF secreted from gastric carcinoma mesenchymal stem cells.

  4. These data demonstrate that selective perturbation of the satellite cell niche results in distinct sarcoma subtypes in a Pax7 (show PAX7 Proteins) lineage-dependent manner.

  5. High Serum level of hepatocyte growth factor is associated with resistance to the treatment with trastuzumab in HER2 (show ERBB2 Proteins)-positive patients with metastatic gastric cancer

  6. Low hemodialysis-induced release of the anti-inflammatory cytokine HGF correlates with impaired quality of life in that group of patients

  7. Treatment of bronchiolitis Obliterans with HGF gene modified MSCs results in reduction of local inflammation and promotion in recovery of allograft trachea histopathology.

  8. Case Report: favorable outcome in hepatitis A complicated with acute renal failure and high hepatocyte growth factor.

  9. Report the application of advanced quantitative fluorescence microscopy techniques to study changes in the oligomerization state of the RTK Met in response to stimulation by its endogenous ligand hepatocyte growth factor.

  10. The findings suggest that the oncogenic activity of hepsin (show HPN Proteins) arises not only from elevated expression level but also from depletion of HAI-1 (show SPINT1 Proteins), events which together trigger gain-of-function activity impacting HGF/MET signalling and epithelial cohesion

Rabbit Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) interaction partners

  1. acute pulmonary embolism associated with an enhanced HGF expression in the lungs, the right ventricle, and the liver

Cow (Bovine) Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) interaction partners

  1. SNPs within bovine HGF gene were significantly associated with growth traits. This will provide a background for application of bovine HGF gene in the selection program in Chinese cattle.

  2. Treatment of the bovine satellite cells (BSC (show SLC12A2 Proteins)) with ephrin-A5 (show EFNA5 Proteins) causes a reduction in velocity with a concomitant increase in directed migration. Treatment of BSC (show SLC12A2 Proteins) with hepatocyte growth factor had no immediate effect on cell motility or migration.

  3. HGF transiently increases gene transcription of angiotensin-converting enzyme (show ACE Proteins)

Pig (Porcine) Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) interaction partners

  1. Combined administration of mesenchymal stem cells overexpressing IGF-1 (show IGF1 Proteins) and HGF enhances neovascularization but moderately improves cardiac regeneration in a porcine model.

  2. In an animal model of acute myocardial infarction relevant to human disease, intracoronary administration of IGF-1 (show IGF1 Proteins)/hepatocyte growth factor (HGF) is a practical and effective strategy to reduce pathological cardiac remodeling.

HGF Protein Profile

Protein Summary

Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with HGF

  • hepatocyte growth factor (HGF)
  • hepatocyte growth factor (Hgf)
  • hepatocyte growth factor (hepapoietin A; scatter factor) (HGF)
  • hepatocyte growth factor (hepapoietin A; scatter factor) (Hgf)
  • hepatocyte growth factor-like (LOC100525120)
  • met proto-oncogene (Met)
  • AI838057 protein
  • c-Met protein
  • C230052L06Rik protein
  • DFNB39 protein
  • F-TCF protein
  • HGF protein
  • HGF/SF protein
  • HGFB protein
  • HGFR protein
  • HPTA protein
  • NK1 protein
  • NK2 protein
  • Par4 protein
  • SF protein
  • SF/HGF protein

Protein level used designations for HGF

hepatocyte growth factor , SF , hepatopoeitin-A , hepatopoietin-A , scatter factor , fibroblast-derived tumor cytotoxic factor , lung fibroblast-derived mitogen , hepapoietin A , HGF alpha-chain , hepatocyte growth factor /scatter factor , HGF receptor , HGF/SF receptor , SF receptor , hepatocyte growth factor receptor , met proto-oncogene tyrosine kinase , proto-oncogene c-Met , scatter factor receptor , tyrosine-protein kinase Met

708316 Macaca mulatta
15234 Mus musculus
24446 Rattus norvegicus
3082 Homo sapiens
100730730 Cavia porcellus
100316908 Oryctolagus cuniculus
403441 Canis lupus familiaris
282879 Bos taurus
395941 Gallus gallus
493705 Felis catus
443075 Ovis aries
100525120 Sus scrofa
17295 Mus musculus
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