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Browse our anti-KIT (KIT) Antibodies

Full name:
anti-Mast/stem Cell Growth Factor Receptor Antibodies (KIT)
On www.antibodies-online.com are 1182 Mast/stem Cell Growth Factor Receptor (KIT) Antibodies from 35 different suppliers available. Additionally we are shipping KIT Kits (41) and KIT Proteins (37) and many more products for this protein. A total of 1267 KIT products are currently listed.
Synonyms:
Bs, c-kit, CD117, Fdc, Gsfsco1, Gsfsco5, Gsfsow3, MGF, PBT, SCFR, SCO1, SCO5, SOW3, Ssm, Tr-kit, W
list all antibodies Gene Name GeneID UniProt
KIT 16590 P05532
KIT 3815 P10721
KIT    

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All available anti-KIT Antibodies

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Top referenced anti-KIT Antibodies

  1. Human Monoclonal KIT Primary Antibody for FACS - ABIN488147 : Shah, Lee, Luo, Jiang, Donker, Akin: Dasatinib (BMS-354825) inhibits KITD816V, an imatinib-resistant activating mutation that triggers neoplastic growth in most patients with systemic mastocytosis. in Blood 2006 (PubMed)
    Show all 7 references for ABIN488147

  2. Human Polyclonal KIT Primary Antibody for WB - ABIN196992 : Lowe: Colipase stabilizes the lid domain of pancreatic triglyceride lipase. in The Journal of biological chemistry 1997 (PubMed)
    Show all 5 references for ABIN196992

  3. Human Polyclonal KIT Primary Antibody for EIA, IHC (p) - ABIN359890 : Wardelmann, Losen, Hans, Neidt, Speidel, Bierhoff, Heinicke, Pietsch, Büttner, Merkelbach-Bruse: Deletion of Trp-557 and Lys-558 in the juxtamembrane domain of the c-kit protooncogene is associated with metastatic behavior of gastrointestinal stromal tumors. in International journal of cancer. Journal international du cancer 2003 (PubMed)
    Show all 4 references for ABIN359890

  4. Human Polyclonal KIT Primary Antibody for FACS, IHC (p) - ABIN392008 : Voytyuk, Lennartsson, Mogi, Caruana, Courtneidge, Ashman, Rönnstrand: Src family kinases are involved in the differential signaling from two splice forms of c-Kit. in The Journal of biological chemistry 2003 (PubMed)
    Show all 4 references for ABIN392008

  5. Human Polyclonal KIT Primary Antibody for IHC (p) - ABIN401646 : Martin, Suggs, Langley, Lu, Ting, Okino, Morris, McNiece, Jacobsen, Mendiaz: Primary structure and functional expression of rat and human stem cell factor DNAs. in Cell 1990 (PubMed)
    Show all 4 references for ABIN401646

  6. Mouse (Murine) Monoclonal KIT Primary Antibody for FACS, IHC (fro) - ABIN114259 : Suda, Okada, Suda, Miura, Ito, Sudo, Hayashi, Nishikawa, Nakauchi: A stimulatory effect of recombinant murine interleukin-7 (IL-7) on B-cell colony formation and an inhibitory effect of IL-1 alpha. in Blood 1989 (PubMed)
    Show all 3 references for ABIN114259

  7. Mouse (Murine) Monoclonal KIT Primary Antibody for FACS - ABIN319617 : Ikuta, Weissman: Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation. in Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)
    Show all 2 references for ABIN319617

  8. Human Monoclonal KIT Primary Antibody for IHC (p), IHC - ABIN151293 : Schultz, Rotunno, Erben, Sommer, Anders, Stern-Straeter, Hofheinz, Hörmann, Sauter: Down-regulation of MMP-2 expression due to inhibition of receptor tyrosine kinases by imatinib and carboplatin in HNSCC. in Oncology reports 2011 (PubMed)
    Show all 2 references for ABIN151293

  9. Mouse (Murine) Monoclonal KIT Primary Antibody for FACS - ABIN114257 : Ogawa, Matsuzaki, Nishikawa, Hayashi, Kunisada, Sudo, Kina, Nakauchi, Nishikawa: Expression and function of c-kit in hemopoietic progenitor cells. in The Journal of experimental medicine 1991 (PubMed)
    Show all 2 references for ABIN114257

  10. Dog (Canine) Polyclonal KIT Primary Antibody for IHC (p) - ABIN115379 : Arber, Tamayo, Weiss: Paraffin section detection of the c-kit gene product (CD117) in human tissues: value in the diagnosis of mast cell disorders. in Human pathology 1998 (PubMed)

More Antibodies against KIT Interaction Partners

Mouse (Murine) Mast/stem Cell Growth Factor Receptor (KIT) interaction partners

  1. Kit inactivation within oocytes also led to premature ovarian failure, albeit via a contrasting phenotype. Despite normal initial complements of primordial follicles, oocytes remained dormant with arrested oocyte maturation. Foxo3 (show FOXO3 Antibodies) protein localization in the nucleus versus cytoplasm explained both mutant phenotypes.

  2. sca-1 (show Ly6a Antibodies) antibody reduces both CD34 (show CD34 Antibodies)+/c-kit+ progenitor cell surge and vascular restenosis after endoluminal vascular injury in a murine model.

  3. These findings indicate the SCF (show KITLG Antibodies)/Kit signaling insufficiency may contribute to the underdevelopment of ICCs and intestinal motility dysfunction upon hypoxia exposure.

  4. we identified important roles for the GATA-2 C-ZnF in bone marrow hematopoiesis via control of c-Kit expression and HSC/HSPC survival.

  5. IMC-G4 cells had an additional novel c-kit gene mutation of KIT-Tyr421Cys which is considered to induce neoplastic transformation of mouse mast cells

  6. gene deficiency does not play a role in the pathogenesis of lupus in B6lpr/lpr (show FAS Antibodies) mice.

  7. suggests FGF-9 has the potential to attenuate vascular cell apoptosis, activate c-Kit progenitor cells, and enhance angiogenesis and neovascularization in C57BL/6 and db/db (show LEPR Antibodies) mice leading to improved cardiac function.

  8. Bone marrow-derived CD117+ hematopoietic progenitor cells differentiate into thymic dendritic cells in the fetal thymus organ culture system in the presence of Flt3L (show FLT3LG Antibodies).

  9. C-kit signaling has a role in proliferation and invasion of colorectal mucinous adenocarcinoma

  10. TAK1 (show NR2C2 Antibodies) and IKK2 (show IKBKB Antibodies) are novel mediators of SCF (show KITLG Antibodies)-induced signaling and potential targets for c-Kit-driven diseases.

Human Mast/stem Cell Growth Factor Receptor (KIT) interaction partners

  1. EGFR (show EGFR Antibodies) expression was observed in 58% and c-KIT expression was seen in 30% of the cases [triple negative breast cancer]

  2. Canonical TGF-beta (show TGFB1 Antibodies) and c-KIT signaling forms a positive, tumor-promoting feedback loop. Disruption of this loop restores TGF-beta (show TGFB1 Antibodies) tumor suppressor function and provides the rationale for targeting the TGF-beta (show TGFB1 Antibodies)/SCF (show KITLG Antibodies) axis as a novel therapeutic strategy for Hepatocellular carcinoma.

  3. We conclude that c-KIT expression is a valuable predictor of prognosis and survival, especially in thick (>4 mm) vulvar melanomas

  4. BRAF (show BRAF Antibodies) mutations are rare events in KIT/PDGFRA (show PDGFRA Antibodies) wild-type gastrointestinal stromal tumors.

  5. Results revealed that Orai1 (show ORAI1 Antibodies)-mediated store-operated Ca(2 (show CA2 Antibodies)+) entry is critical for gastrointestinal stromal tumor cell proliferation via c-KIT and ERK (show EPHB2 Antibodies) signaling pathway activation.

  6. C646 treatment attenuated ETV1 (show ETV1 Antibodies) protein expression and inactivated KIT-dependent pathways. Taken together, the present study suggests that CBP/p300 (show CREBBP Antibodies) may serve as novel antineoplastic targets and that use of the selective HAT (show MGEA5 Antibodies) inhibitor C646 is a promising antitumor strategy for Gastrointestinal stromal tumors.

  7. Of the 66 apocrine lesions, 62 (94 %) did not express C-KIT compared to 4/63 (6 %) of the normal glands

  8. analyzed biopsy specimens for the presence of BRAF (show BRAF Antibodies) mutations in exon 15

  9. Combination of mutant-specific BRAF (show BRAF Antibodies) and CD117 ICC with cytopathology may facilitate the PTC (show F9 Antibodies)-risk stratification in thyroid FNAB specimens.

  10. Expression of c-kit was associated with poorer overall survival (p = 0.011), while ALDH1A1 (show ALDH1A1 Antibodies) expression was associated with shorter recurrence-free survival (p = 0.036).

Pig (Porcine) Mast/stem Cell Growth Factor Receptor (KIT) interaction partners

  1. mRNA expression of c-kit and SCF was decreased in gallbladder tissues in the HCD group. Consistent with the findings of RT-PCR, a lower expression level of c-kit and SCF protein was also observed in HCD animals.

  2. Delayed enrichment for c-kit and inducing cardiac differentiation attenuated protective effects of BMSCs' transplantation in pig model of acute myocardial infarction.

  3. Pravastatin improves function in hibernating myocardium by mobilizing CD133+ and cKit+ bone marrow progenitor cells and promoting myocytes to reenter the growth phase of the cardiac cell cycle.

Cow (Bovine) Mast/stem Cell Growth Factor Receptor (KIT) interaction partners

  1. FGF7 (show FGF7 Antibodies) may be an important regulator for oocyte growth and its action is mediated via the KIT/KITLG (show KITLG Antibodies) signaling pathway.

KIT Antigen Profile

Antigen Summary

This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with KIT

  • kit oncogene (Kit) antibody
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT) antibody
  • Bs antibody
  • c-kit antibody
  • CD117 antibody
  • Fdc antibody
  • Gsfsco1 antibody
  • Gsfsco5 antibody
  • Gsfsow3 antibody
  • MGF antibody
  • PBT antibody
  • SCFR antibody
  • SCO1 antibody
  • SCO5 antibody
  • SOW3 antibody
  • Ssm antibody
  • Tr-kit antibody
  • W antibody

Protein level used designations for KIT

Dominant white spotting , SCFR , Steel Factor Receptor , belly-spot , c-kit proto-oncogene protein , dominant spotting , mast/stem cell growth factor receptor Kit , proto-oncogene c-Kit , proto-oncogene tyrosine-protein kinase Kit , spotted sterile male , tyrosine-protein kinase Kit , p145 c-kit , piebald trait protein , soluble KIT variant 1 , v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein , c-kit , c-KIT gene1 , receptor tyrosine kinase c-kit , c-kit receptor , mast cell growth factor receptor

GENE ID SPECIES
16590 Mus musculus
3815 Homo sapiens
378783 Gallus gallus
403811 Canis lupus familiaris
396810 Sus scrofa
280832 Bos taurus
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