Browse our anti-KIT (KIT) Antibodies

Full name:
anti-Mast/stem Cell Growth Factor Receptor Antibodies (KIT)
On www.antibodies-online.com are 1237 Mast/stem Cell Growth Factor Receptor (KIT) Antibodies from 35 different suppliers available. Additionally we are shipping KIT Kits (42) and KIT Proteins (39) and many more products for this protein. A total of 1326 KIT products are currently listed.
Synonyms:
Bs, c-kit, CD117, Fdc, Gsfsco1, Gsfsco5, Gsfsow3, MGF, PBT, SCFR, SCO1, SCO5, SOW3, Ssm, Tr-kit, W
list all antibodies Gene Name GeneID UniProt
KIT 16590 P05532
KIT 3815 P10721
KIT    

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All available anti-KIT Antibodies

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Top referenced anti-KIT Antibodies

  1. Human Monoclonal KIT Primary Antibody for FACS - ABIN488147 : Shah, Lee, Luo, Jiang, Donker, Akin: Dasatinib (BMS-354825) inhibits KITD816V, an imatinib-resistant activating mutation that triggers neoplastic growth in most patients with systemic mastocytosis. in Blood 2006 (PubMed)
    Show all 7 references for 488147

  2. Human Polyclonal KIT Primary Antibody for FACS, IHC (p) - ABIN392008 : Wardelmann, Losen, Hans, Neidt, Speidel, Bierhoff, Heinicke, Pietsch, Büttner, Merkelbach-Bruse: Deletion of Trp-557 and Lys-558 in the juxtamembrane domain of the c-kit protooncogene is associated with metastatic behavior of gastrointestinal stromal tumors. in International journal of cancer. Journal international du cancer 2003 (PubMed)
    Show all 4 references for 392008

  3. Human Polyclonal KIT Primary Antibody for EIA, IHC (p) - ABIN359890 : Lennartsson, Wernstedt, Engström, Hellman, Rönnstrand: Identification of Tyr900 in the kinase domain of c-Kit as a Src-dependent phosphorylation site mediating interaction with c-Crk. in Experimental cell research 2003 (PubMed)
    Show all 4 references for 359890

  4. Human Polyclonal KIT Primary Antibody for IF (cc), IF (p) - ABIN1387260 : Chen, Chen, Lin, Hu, Liao: Resveratrol inhibits alpha-melanocyte-stimulating hormone signaling, viability, and invasiveness in melanoma cells. in Evidence-based complementary and alternative medicine : eCAM 2013 (PubMed)
    Show all 3 references for 1387260

  5. Mouse (Murine) Monoclonal KIT Primary Antibody for FACS, IHC (fro) - ABIN114259 : Suda, Okada, Suda, Miura, Ito, Sudo, Hayashi, Nishikawa, Nakauchi: A stimulatory effect of recombinant murine interleukin-7 (IL-7) on B-cell colony formation and an inhibitory effect of IL-1 alpha. in Blood 1989 (PubMed)
    Show all 3 references for 114259

  6. Dog (Canine) Polyclonal KIT Primary Antibody for IF (p), IHC (p) - ABIN671721 : Zhang, Huang, Wu, Yang, Song, Chen, Fan, Wang: Cardiac stem cells differentiate into sinus node-like cells. in The Tohoku journal of experimental medicine 2010 (PubMed)
    Show all 3 references for 671721

  7. Mouse (Murine) Monoclonal KIT Primary Antibody for FACS - ABIN114257 : Ogawa, Matsuzaki, Nishikawa, Hayashi, Kunisada, Sudo, Kina, Nakauchi, Nishikawa: Expression and function of c-kit in hemopoietic progenitor cells. in The Journal of experimental medicine 1991 (PubMed)
    Show all 2 references for 114257

  8. Human Monoclonal KIT Primary Antibody for IHC (p), IHC - ABIN151293 : Schultz, Rotunno, Erben, Sommer, Anders, Stern-Straeter, Hofheinz, Hörmann, Sauter: Down-regulation of MMP-2 expression due to inhibition of receptor tyrosine kinases by imatinib and carboplatin in HNSCC. in Oncology reports 2011 (PubMed)
    Show all 2 references for 151293

  9. Dog (Canine) Polyclonal KIT Primary Antibody for IHC (p) - ABIN115379 : Arber, Tamayo, Weiss: Paraffin section detection of the c-kit gene product (CD117) in human tissues: value in the diagnosis of mast cell disorders. in Human pathology 1998 (PubMed)

  10. Human Polyclonal KIT Primary Antibody for IF (p), IHC (p) - ABIN743393 : Halsey, Thamm, Weishaar, Burton, Charles, Gustafson, Avery, Ehrhart: Expression of Phosphorylated KIT in Canine Mast Cell Tumor. in Veterinary pathology 2017 (PubMed)

More Antibodies against KIT Interaction Partners

Mouse (Murine) Mast/stem Cell Growth Factor Receptor (KIT) interaction partners

  1. C-kit-positive hematopoietic stem/progenitor cells expressed significantly higher of Nox1 (show NOX1 Antibodies) and catalase (show CAT Antibodies), but less of lactoperoxidase (show LPO Antibodies) than in matured mononuclear cells.

  2. c-KIT signaling regulates self-renewal capacity and prevents neurodifferentiation in culture.

  3. These findings identify functional redundancy among Kit-dependent hematopoietic lineages and establish an unanticipated capacity of megakaryocytes to mediate IL-1 (show IL1A Antibodies)-driven systemic inflammatory disease.

  4. WNT (show WNT2 Antibodies) signaling at an early stage (E12 (show ELSPBP1 Antibodies)-E15) of submandibular salivary gland (SMG (show SNRPG Antibodies)) development inhibits end bud morphogenesis and differentiation into proacini by suppressing Kit expression.

  5. c-kit can reduce inflammation, positively modulate airway remodeling, and improve function in a mouse model of airway hyperresponsiveness

  6. Kit inactivation within oocytes also led to premature ovarian failure, albeit via a contrasting phenotype. Despite normal initial complements of primordial follicles, oocytes remained dormant with arrested oocyte maturation. Foxo3 (show FOXO3 Antibodies) protein localization in the nucleus versus cytoplasm explained both mutant phenotypes.

  7. sca-1 (show Ly6a Antibodies) antibody reduces both CD34 (show CD34 Antibodies)+/c-kit+ progenitor cell surge and vascular restenosis after endoluminal vascular injury in a murine model.

  8. These findings indicate the SCF (show KITLG Antibodies)/Kit signaling insufficiency may contribute to the underdevelopment of ICCs and intestinal motility dysfunction upon hypoxia exposure.

  9. we identified important roles for the GATA-2 C-ZnF in bone marrow hematopoiesis via control of c-Kit expression and HSC/HSPC survival.

  10. IMC-G4 cells had an additional novel c-kit gene mutation of KIT-Tyr421Cys which is considered to induce neoplastic transformation of mouse mast cells

Human Mast/stem Cell Growth Factor Receptor (KIT) interaction partners

  1. c-KIT overexpressing cells showed a regression of typical morphological features of malignancy. Taken together these results suggest that c-KIT could be involved in the differentiation of thyroid cells and in tumor progression

  2. low level of MITF (show MITF Antibodies) cooperates with oncogenic KIT to transform melanocytes. Activation of the cAMP pathway in transformed (L576P)KIT melanocytes stimulated MITF (show MITF Antibodies) expression, and reduced cellular proliferation and sphere formation. These findings highlight the essential role of MITF (show MITF Antibodies) in revealing the oncogenic activity of KIT in melanocytes and suggest that the cAMP pathway is a therapeutic target in KIT-mutated melanoma.

  3. This previously unexplored G4-G4 interaction modulates both the conformation and the stability of the overall arrangement of the c-KIT promoter. It is not supported by stacking of single nucleotides but refers to a G4-G4 interaction surface surrounded by a two-nucleotides loop that might represent a reliable unprecedented target for anticancer therapy.

  4. Transcription factor-induced activation of cardiac gene expression in human c-kit+ cardiac progenitor cells has been reported.

  5. It was found that the absence of mutations in the SRSF2 (show SRSF2 Antibodies), ASXL1 (show ASXL1 Antibodies), and/or RUNX1gene panel at baseline and a reduction of the KIT D816V allele burden more than 25% at month 6 are the most favorable predictors for improved survival in midostaurin-treated advanced systemic mastocytosis patients.

  6. Point mutation in c-kit gene is associated with sequential development of an ovarian mixed germ cell tumor and systemic mastocytosis with chronic myelomonocytic leukemia.

  7. This study assesses MYB (show MYB Antibodies), CD117 and SOX-10 (show SOX10 Antibodies) expression in cutaneous adnexal tumors.

  8. EGFR (show EGFR Antibodies) expression was observed in 58% and c-KIT expression was seen in 30% of the cases [triple negative breast cancer]

  9. Canonical TGF-beta (show TGFB1 Antibodies) and c-KIT signaling forms a positive, tumor-promoting feedback loop. Disruption of this loop restores TGF-beta (show TGFB1 Antibodies) tumor suppressor function and provides the rationale for targeting the TGF-beta (show TGFB1 Antibodies)/SCF (show KITLG Antibodies) axis as a novel therapeutic strategy for Hepatocellular carcinoma.

  10. We conclude that c-KIT expression is a valuable predictor of prognosis and survival, especially in thick (>4 mm) vulvar melanomas

Pig (Porcine) Mast/stem Cell Growth Factor Receptor (KIT) interaction partners

  1. mRNA expression of c-kit and SCF was decreased in gallbladder tissues in the HCD group. Consistent with the findings of RT-PCR, a lower expression level of c-kit and SCF protein was also observed in HCD animals.

  2. Delayed enrichment for c-kit and inducing cardiac differentiation attenuated protective effects of BMSCs' transplantation in pig model of acute myocardial infarction.

  3. Pravastatin improves function in hibernating myocardium by mobilizing CD133+ and cKit+ bone marrow progenitor cells and promoting myocytes to reenter the growth phase of the cardiac cell cycle.

Cow (Bovine) Mast/stem Cell Growth Factor Receptor (KIT) interaction partners

  1. FGF7 (show FGF7 Antibodies) may be an important regulator for oocyte growth and its action is mediated via the KIT/KITLG (show KITLG Antibodies) signaling pathway.

KIT Antigen Profile

Antigen Summary

This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with KIT

  • kit oncogene (Kit) antibody
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT) antibody
  • Bs antibody
  • c-kit antibody
  • CD117 antibody
  • Fdc antibody
  • Gsfsco1 antibody
  • Gsfsco5 antibody
  • Gsfsow3 antibody
  • MGF antibody
  • PBT antibody
  • SCFR antibody
  • SCO1 antibody
  • SCO5 antibody
  • SOW3 antibody
  • Ssm antibody
  • Tr-kit antibody
  • W antibody

Protein level used designations for KIT

Dominant white spotting , SCFR , Steel Factor Receptor , belly-spot , c-kit proto-oncogene protein , dominant spotting , mast/stem cell growth factor receptor Kit , proto-oncogene c-Kit , proto-oncogene tyrosine-protein kinase Kit , spotted sterile male , tyrosine-protein kinase Kit , p145 c-kit , piebald trait protein , soluble KIT variant 1 , v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein , c-kit , c-KIT gene1 , receptor tyrosine kinase c-kit , c-kit receptor , mast cell growth factor receptor

GENE ID SPECIES
16590 Mus musculus
3815 Homo sapiens
378783 Gallus gallus
403811 Canis lupus familiaris
396810 Sus scrofa
280832 Bos taurus
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