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Human KIT Ligand Protein expressed in Escherichia coli (E. coli) - ABIN2018375
Lili, Chaozhan, Xindu: Expression, renaturation and simultaneous purification of recombinant human stem cell factor in Escherichia coli. in Biotechnology letters 2006
Show all 4 Pubmed References
Mouse (Murine) KIT Ligand Protein expressed in Escherichia coli (E. coli) - ABIN413775
Fukuda, Bian, King, Pelus: The chemokine GRObeta mobilizes early hematopoietic stem cells characterized by enhanced homing and engraftment. in Blood 2007
Show all 2 Pubmed References
Human KIT Ligand Protein expressed in Escherichia coli (E. coli) - ABIN413772
Kinzfogl, Hangoc, Broxmeyer: Neurexophilin 1 suppresses the proliferation of hematopoietic progenitor cells. in Blood 2011
Mouse (Murine) KIT Ligand Protein expressed in Escherichia coli (E. coli) - ABIN804039
Vas, Wandhoff, Dörr, Niebel, Geiger: Contribution of an aged microenvironment to aging-associated myeloproliferative disease. in PLoS ONE 2012
results suggest that SCF can accelerate cell homing and the maturation of the pulp-dentin complex in human immature teeth.
SCF is a critical regulatory factor for conceptus development and implantation during pregnancy in pigs.
the critical physiological role of the KIT-ET3 (show EDN3 Proteins)-NO pathway in fulfilling high demand (exceeding basal level) of endothelium-dependent NO generation for coping with atherosclerosis, pregnancy, and aging, is reported.
results revealed that the Th17-mediated inflammatory environment promotes mast cell accumulation through keratinocyte-derived SCF
Bone marrow adipocytes synthesize SCF, promoting hematopoietic stem cell proliferation/regeneration.
Hypoxia microenvironment in hepatocellular carcinoma up-regulates HIF2 (show EPAS1 Proteins)/SCF expression, which in turn promotes angiogenesis and HCC (show FAM126A Proteins) metastasis.
Insights into the transmembrane helix associations of Kit ligand have been reported.
There were no significant differences in CD334 (show FGFR4 Proteins)-SCF double-positive FB and CD31 (show HBA1 Proteins)-SCF double-positive EC levels between the two periapical tissue groups (P > 0.05). CD14 (show NDUFA2 Proteins)-SCF double-positive MP density was considerably higher in periapical granulomas than in cysts (P < 0.01).
A significant association of rs995030 of the KITLG gene with the development of testicular germ cell tumors (p = 0.029 for the allele G, p = 0.0124 for the genotype GG) was revealed.
Overexpression of SCF is associated with Lewis lung carcinoma.
MAPK3 (show MAPK3 Proteins)/1 participates in primordial follicle activation through mTORC1-KITL signaling.
MicroRNA-205 maintains T cell development following stress by regulating Foxn1 (show FOXN2 Proteins) and its two regulated targets, stem cell factor and ccl25 (show CCL25 Proteins), following stress.
These findings indicate the SCF/Kit signaling insufficiency may contribute to the underdevelopment of ICCs and intestinal motility dysfunction upon hypoxia exposure.
SCF/c-kit signaling may potentiate chronic hypoxia-induced vascular remodeling by modulating ERK activation. Inhibition of c-kit activity may be a potential strategy to alleviate PH
Kit ligand regulates the subcellular localization of FOXO3 (show FOXO3 Proteins) in the neonatal mouse ovary.
The results of this study indicate that c-kit/KITL signalling also occurs in the human ovary, as established in various animal models, and may involve previously unknown autocrine signalling
study suggests extracellular HMGB1 (show HMGB1 Proteins) participates in NLRP3 (show NLRP3 Proteins) inflammasome activity and regulates IL-1beta (show IL1B Proteins) associated sterile inflammation induced by MWCNT
SCF/c-kit signaling was required for TPA (show PLAT Proteins)-induced migration and differentiation of hair follicle melanocytes.
These results show that mast cell deficiency, in the absence of Kit mutations, plays no role in the regulation of weight gain or insulin (show INS Proteins) resistance.
Oocyte-derived signals interact locally to mediate granulosa and theca cell function. SCF has a role in modulating this local interaction.
little evidence was found for the KITLG gene being linked to variation in colour
FGF7 (show FGF7 Proteins) may be an important regulator for oocyte growth and its action is mediated via the KIT/KITLG signaling pathway.
Results suggest that the KITLG gene is a strong candidate gene affecting litter size in goats.
This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene.
, c-Kit ligand
, familial progressive hyperpigmentation 2
, kit ligand
, mast cell growth factor
, steel factor
, stem cell factor
, C-kit ligand
, Steel factor
, cloud gray
, hematopoietic growth factor KL
, steel factor/kit ligand
, stem cell factor KL-1
, KIT ligand precursor form 1
, KIT ligand precursor form 4
, c-kit ligand
, stem cell factor, CSF
, mast cell growth factor (white heifer disease)
, Mast cell growth factor
, stem cell factor homolog