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Browse our KIT Ligand Proteins (KITLG)

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KIT Ligand Proteins (KITLG)
On are 147 KIT Ligand (KITLG) Proteins from 23 different suppliers available. Additionally we are shipping KIT Ligand Antibodies (250) and KIT Ligand Kits (104) and many more products for this protein. A total of 515 KIT Ligand products are currently listed.
710-712, blz, Clo, Con, contrasted, CSF, FPH2, Gb, KITL, Kitlg, KL-1, Mgf, scf, SF, SHEP7, Sl, SLF, steel, Xkl-1, Xsl, Xsl-1, Xsl-2
list all proteins Gene Name GeneID UniProt
KITLG 4254 P21583
KITLG 17311 P20826
KITLG 60427 P21581

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KIT Ligand Proteins (KITLG) by Origin

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Top referenced KIT Ligand Proteins

  1. Human KIT Ligand Protein expressed in Escherichia coli (E. coli) - ABIN2666674 : Jin, Shido, Kopp, Petit, Shmelkov, Young, Hooper, Amano, Avecilla, Heissig, Hattori, Zhang, Hicklin, Wu, Zhu, Dunn, Salari, Werb, Hackett, Crystal, Lyden, Rafii: Cytokine-mediated deployment of SDF-1 induces revascularization through recruitment of CXCR4+ hemangiocytes. in Nature medicine 2006 (PubMed)
    Show all 5 references for ABIN2666674

  2. Mouse (Murine) KIT Ligand Protein expressed in Escherichia coli (E. coli) - ABIN413775 : Fukuda, Bian, King, Pelus: The chemokine GRObeta mobilizes early hematopoietic stem cells characterized by enhanced homing and engraftment. in Blood 2007 (PubMed)
    Show all 2 references for ABIN413775

  3. Mouse (Murine) KIT Ligand Protein expressed in HEK-293 Cells - ABIN2181732 : Lu, Clogston, Wypych, Parker, Lee, Swiderek, Baltera, Patel, Chang, Brankow: Post-translational processing of membrane-associated recombinant human stem cell factor expressed in Chinese hamster ovary cells. in Archives of biochemistry and biophysics 1992 (PubMed)
    Show all 2 references for ABIN2181732

  4. Human KIT Ligand Protein expressed in Escherichia coli (E. coli) - ABIN413772 : Kinzfogl, Hangoc, Broxmeyer: Neurexophilin 1 suppresses the proliferation of hematopoietic progenitor cells. in Blood 2011 (PubMed)

  5. Mouse (Murine) KIT Ligand Protein expressed in Baculovirus infected Insect Cells - ABIN2007880 : Paulhe, Imhof, Wehrle-Haller: A specific endoplasmic reticulum export signal drives transport of stem cell factor (Kitl) to the cell surface. in The Journal of biological chemistry 2004 (PubMed)

More Proteins for KIT Ligand Interaction Partners

Human KIT Ligand (KITLG) interaction partners

  1. Na+/H+ antiporter (show SLC9A1 Proteins) inhibition induces cell death in TF-1 erythroleukemia cells stimulated by the stem cell factor

  2. IL-7 (show IL7 Proteins) and SCF are elevated for a prolonged period after double umbilical cord blood transplantation and persistently high levels of these cytokines may correlate with worse clinical outcomes.

  3. Allelic Mutations of KITLG, Encoding KIT Ligand, Cause Asymmetric and Unilateral Hearing Loss and Waardenburg Syndrome Type 2.

  4. Foxc1 (show FOXC1 Proteins) is essential for progenitor cell development and maintenance of bone marrow niches for these cells upregulating CXCL12 (show CXCL12 Proteins) and SCF expression and inhibiting of adipogenic processes in cell progenitors. (Review)

  5. Results identified SCF as a direct target of HIF-1 in pancreatic cancer. SCF/c-kit promoted invasion and proliferation of pancreatic cancer cells and may be a new target for the treatment of pancreatic cancer.

  6. we found that Kl treatment impairs Nodal mRNA expression and Fgf9-mediated Nanos2 (show NANOS2 Proteins) induction, reinforcing the antagonistic effect of these two growth factors on the meiotic fate of male germ cells

  7. A functional p53 (show TP53 Proteins) responsive polymorphism in KITLG, rs4590952, does not affect the risk of breast cancer.

  8. Paracrine signaling from SCF to KIT, between differentiated tumor cells and undifferentiated stem-like tumor cells, helps maintain the stem-like features of tumor cells, predominantly under conditions of hypoxia.

  9. KIT and KITLG are expressed by a subset of human colon tumors. KIT signaling promotes growth of colon cancer cells and organoids in culture and xenograft tumors in mice via its ligand, KITLG, in an autocrine or paracrine manner.

  10. High SCF expression is associated with metastasis in non-small cell lung cancers.

Mouse (Murine) KIT Ligand (KITLG) interaction partners

  1. The results of this study indicate that c-kit/KITL signalling also occurs in the human ovary, as established in various animal models, and may involve previously unknown autocrine signalling

  2. study suggests extracellular HMGB1 (show HMGB1 Proteins) participates in NLRP3 (show NLRP3 Proteins) inflammasome activity and regulates IL-1beta (show IL1B Proteins) associated sterile inflammation induced by MWCNT

  3. SCF/c-kit signaling was required for TPA (show PLAT Proteins)-induced migration and differentiation of hair follicle melanocytes.

  4. These results show that mast cell deficiency, in the absence of Kit mutations, plays no role in the regulation of weight gain or insulin (show INS Proteins) resistance.

  5. overexpression of Snail (show SNAI1 Proteins) in PDAC cells increased SCF levels, and the media conditioned by Snail (show SNAI1 Proteins)-expressing PDAC cells promoted mast cell migration.

  6. Stem cell factor is essential for preserving reconstitution capacity of ex vivo expanded cord blood CD34 (show CD34 Proteins)(+) cells in Immunocompromised mice.

  7. Stem cell factor (SCF), but not interleukin-3 (IL-3 (show Il3 Proteins)), is a major effector of HSC (show FUT1 Proteins) maturation during embryonic day E9-E10.

  8. High stem cell factor expression is associated with breast cancer metastasis.

  9. the SCF-c-Kit-Akt (show AKT1 Proteins) physiologic pathway protects osteoblasts from HO-induced damages, and might minimize the risk of osteonecrosis caused by oxidative stress

  10. SCF+G-CSF (show CSF3 Proteins) treatment in chronic stroke remodels neural circuits in the aged brain

Pig (Porcine) KIT Ligand (KITLG) interaction partners

  1. Oocyte-derived signals interact locally to mediate granulosa and theca cell function. SCF has a role in modulating this local interaction.

  2. little evidence was found for the KITLG gene being linked to variation in colour

Cow (Bovine) KIT Ligand (KITLG) interaction partners

  1. FGF7 (show FGF7 Proteins) may be an important regulator for oocyte growth and its action is mediated via the KIT/KITLG signaling pathway.

Goat KIT Ligand (KITLG) interaction partners

  1. Results suggest that the KITLG gene is a strong candidate gene affecting litter size in goats.

KIT Ligand (KITLG) Protein Profile

Protein Summary

This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with KIT Ligand (KITLG)

  • KIT ligand (kitlg)
  • KIT ligand (KITLG)
  • kit ligand (Kitl)
  • KIT ligand (Kitlg)
  • 710-712 protein
  • blz protein
  • Clo protein
  • Con protein
  • contrasted protein
  • CSF protein
  • FPH2 protein
  • Gb protein
  • KITL protein
  • Kitlg protein
  • KL-1 protein
  • Mgf protein
  • scf protein
  • SF protein
  • SHEP7 protein
  • Sl protein
  • SLF protein
  • steel protein
  • Xkl-1 protein
  • Xsl protein
  • Xsl-1 protein
  • Xsl-2 protein

Protein level used designations for KIT Ligand Proteins (KITLG)

KIT ligand , c-Kit ligand , familial progressive hyperpigmentation 2 , kit ligand , mast cell growth factor , steel factor , stem cell factor , C-kit ligand , Steel factor , cloud gray , grizzle-belly , hematopoietic growth factor KL , steel factor/kit ligand , stem cell factor KL-1 , KIT ligand precursor form 1 , KIT ligand precursor form 4 , MGF , SCF , c-kit ligand , stem cell factor, CSF , mast cell growth factor (white heifer disease) , Mast cell growth factor , stem cell factor homolog

379817 Xenopus laevis
452114 Pan troglodytes
574254 Macaca mulatta
733847 Xenopus (Silurana) tropicalis
4254 Homo sapiens
17311 Mus musculus
60427 Rattus norvegicus
396028 Gallus gallus
403507 Canis lupus familiaris
397509 Sus scrofa
281885 Bos taurus
100860807 Capra hircus
100034127 Equus caballus
493937 Felis catus
443371 Ovis aries
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