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Browse our Neuregulin 4 Proteins (NRG4)

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Neuregulin 4 Proteins (NRG4)
On are 10 Neuregulin 4 (NRG4) Proteins from 6 different suppliers available. Additionally we are shipping Neuregulin 4 Antibodies (36) and Neuregulin 4 Kits (15) and many more products for this protein. A total of 64 Neuregulin 4 products are currently listed.
AI552600, HRG4
list all proteins Gene Name GeneID UniProt
Rat NRG4 NRG4 690919  
NRG4 145957 Q8WWG1
NRG4 83961 Q9WTX4

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Neuregulin 4 Proteins (NRG4) by Origin

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Top referenced Neuregulin 4 Proteins

  1. Human Neuregulin 4 Protein expressed in Wheat germ - ABIN1313026 : Liu, Tefft, Roberts, Zhang, Ren, Li, Huang, Zhang, Phillips, Wu: Cardioprotective proteins upregulated in the liver in response to experimental myocardial ischemia. in American journal of physiology. Heart and circulatory physiology 2012 (PubMed)

More Proteins for Neuregulin 4 Interaction Partners

Human Neuregulin 4 (NRG4) interaction partners

  1. NRG4 and its receptor ErbB4 (show ERBB4 Proteins) are present in human breast milk and developing human intestine, respectively. Thus, NRG4-ErbB4 (show ERBB4 Proteins) signaling may be a novel pathway for therapeutic intervention or prevention in NEC.

  2. Nrg4 might have a protective role in the development of Non-alcoholic fatty liver disease (NAFLD).

  3. results establish Nrg4 as a brown fat-enriched endocrine factor with therapeutic potential for the treatment of obesity-associated disorders, including type 2 diabetes and nonalcoholic fatty liver disease (NAFLD).

  4. Pharmacological inhibition of PI3K (show PIK3CA Proteins)/Akt (show AKT1 Proteins) signaling reversed the anti-apoptotic effects of NRG4, confirming the role of this cascade in NRG4-induced cell survival

  5. The recombinant neuregulin 4 induced the tyrosine phosphorylation of HER4 (show ERBB4 Proteins).

  6. NRG4 overexpression is associated with advanced-stage prostate cancer

  7. describes a novel splice variant of the NRG4 gene, NRG4A2, which encodes a C-terminal region containing a predicted type I PDZ-binding peptide (show HP Proteins)

  8. NRG4 was positive in almost all breast cancers studied.

  9. Neuregulin-4 expression is downregulated during urinary bladder cancer progression

Mouse (Murine) Neuregulin 4 (NRG4) interaction partners

  1. Pharmacological inhibition of PI3K/Akt (show AKT1 Proteins) signaling reversed the anti-apoptotic effects of NRG4, confirming the role of this cascade in NRG4-induced cell survival

Neuregulin 4 (NRG4) Protein Profile

Protein Summary

The neuregulins, including NRG4, activate type-1 growth factor receptors (see EGFR\; MIM 131550) to initiating cell-to-cell signaling through tyrosine phosphorylation (Harari et al., 1999

Alternative names and synonyms associated with Neuregulin 4 (NRG4)

  • neuregulin 4 (NRG4)
  • neuregulin 4 (LOC100226066)
  • neuregulin 4 (Nrg4)
  • neuregulin 4 (LOC100347220)
  • AI552600 protein
  • HRG4 protein

Protein level used designations for Neuregulin 4 Proteins (NRG4)

neuregulin 4 , pro-neuregulin-4, membrane-bound isoform , heregulin 4 , pro-NRG4

453770 Pan troglodytes
707378 Macaca mulatta
100226066 Taeniopygia guttata
690919 Rattus norvegicus
145957 Homo sapiens
83961 Mus musculus
415354 Gallus gallus
100347220 Oryctolagus cuniculus
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