You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our NFAT5 Proteins (NFAT5)

Full name:
Nuclear Factor of Activated T-Cells 5, Tonicity-Responsive Proteins (NFAT5)
On are 3 Nuclear Factor of Activated T-Cells 5, Tonicity-Responsive (NFAT5) Proteins from 2 different suppliers available. Additionally we are shipping NFAT5 Antibodies (75) and NFAT5 Kits (1) and many more products for this protein. A total of 85 NFAT5 products are currently listed.
AI225870, B130038B15Rik, CAG-8, CAG80, DKFZp469P1514, mKIAA0827, NF-AT5, Nfat, NFAT5, NFATL1, NFATZ, OREBP, TONEBP, wu:fi46f11, zgc:63502
list all proteins Gene Name GeneID UniProt
NFAT5 54446  
NFAT5 10725 O94916
Rat NFAT5 NFAT5 307820  

Show all synonyms

NFAT5 Proteins (NFAT5) by Origin

Select your origin of interest

More Proteins for NFAT5 Interaction Partners

Mouse (Murine) Nuclear Factor of Activated T-Cells 5, Tonicity-Responsive (NFAT5) interaction partners

  1. In vivo, osmotic stress up-regulates the SCTR (show SCTR Proteins) gene in the kidney cortex and medulla of wild-type mice, but does not do so in NFAT5(+/-) mice.

  2. TonEBP suppresses adipogenesis and insulin (show INS Proteins) sensitivity by blocking epigenetic transition of PPARgamma2 (show PPARG Proteins)

  3. TonEBP is a critical regulator of neuroinflammation and blood-brain barrier leakage in kainic acid-induced seizures.

  4. PKC-alpha contributes to high NaCl-dependent activation of NFAT5 through ERK1/2.

  5. these data support a novel function of the XO-NFAT5 axis in macrophage activation and TLR-induced arthritis

  6. Suggest that biomechanical stretch is sufficient to activate NFAT5 both in native and cultured VSMCs where it regulates the expression of tenascin-C (show TNC Proteins).

  7. Together, these results clearly demonstrated that hyperglycemia-induced TonEBP plays a crucial role in increasing aldose reductase (show AKR1B1 Proteins) and PKCdelta (show PKCd Proteins) levels and leading to apoptotic death.

  8. Data indicate that in transgenic mice overexpressing Sfmbt2 10th intron-hosted miR (show MLXIP Proteins)-466a-3p, significant down-regulation of Nfat5 and many other osmoregulation-related genes was observed in both the renal cortex and medulla.

  9. NFAT5 is part of a protective mechanism that limits renal damage induced by IRI.

  10. NFAT5 induction by the pre-T-cell receptor (show PTCRA Proteins) serves as a selective survival signal in T-lymphocyte development.

Human Nuclear Factor of Activated T-Cells 5, Tonicity-Responsive (NFAT5) interaction partners

  1. The hyperosmotic AR gene expression was dependent on activation of metalloproteinases, autocrine/paracrine TGF-beta (show TGFB1 Proteins) signaling, activation of p38 MAPK (show MAPK14 Proteins), ERK1/2, and PI3K (show PIK3CA Proteins) signal transduction pathways, and the transcriptional activity of NFAT5.

  2. Conclusion. miR-20b acts as a tumor suppressor in the development of thymoma and thymoma-associated myasthenia gravis. The tumor suppressive function of miR-20b in thymoma could be due to its inhibition of NFAT signaling by repression of NFAT5 and CAMTA1 expression.

  3. The hyperosmotic, but not the hypoxic, PlGF (show PGF Proteins) gene expression was in part mediated by NFAT5.

  4. Proteins associated with and binding NH2-terminal region of NFAT5.NUP160 (show NUP160 Proteins) and NUP205 contribute to regulation of NFAT5 transcriptional activity

  5. Our data demonstrates the involvement of TonEBP in the mechanisms responsible for osmoadaptation to hyperosmolar stress in retinal pigment epithelium cells.

  6. Additionally, in peritoneal dialysis the cells of the peritoneal cavity are repeatedly exposed to a rise and fall in osmotic concentrations. Here we review the current information about NFAT5 in uremic patients and patients on peritoneal dialysis.

  7. Results suggest that the NFAT5 gene, which is upregulated a few hours after cocaine exposure, may be involved in the genetic predisposition to cocaine dependence.

  8. NFAT5 pathway activation might have a relevant role in inflammatory breast cancer pathogenesis

  9. Real-time PCR and Western blot analysis confirmed up-regulation of NFAT5 mRNA and NFAT5 nuclear content in human preeclamptic placentas

  10. These results indicate that NFAT5 plays important roles in proliferation and migration of human lung adenocarcinoma cells through regulating AQP5 (show AQP5 Proteins) expression, providing a new therapeutic option for lung adenocarcinoma therapy.

NFAT5 Protein Profile

Protein Summary

The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with NFAT5

  • nuclear factor of activated T-cells 5, tonicity-responsive (NFAT5)
  • nuclear factor of activated T-cells 5, tonicity-responsive (nfat5)
  • nuclear factor of activated T cells 5 (Nfat5)
  • nuclear factor of activated T-cells 5, tonicity-responsive (Nfat5)
  • AI225870 protein
  • B130038B15Rik protein
  • CAG-8 protein
  • CAG80 protein
  • DKFZp469P1514 protein
  • mKIAA0827 protein
  • NF-AT5 protein
  • Nfat protein
  • NFAT5 protein
  • NFATL1 protein
  • NFATZ protein
  • OREBP protein
  • TONEBP protein
  • wu:fi46f11 protein
  • zgc:63502 protein

Protein level used designations for NFAT5

nuclear factor of activated T-cells 5 , nuclear factor of activated T-cells 5, tonicity-responsive , nuclear factor of activated T-cells 5-like , NF-AT5 , T-cell transcription factor NFAT5 , rel domain-containing transcription factor NFAT5 , tonicity-responsive enhancer binding protein , NFAT-like protein 1 , TonE-binding protein , glutamine rich protein H65 , osmotic response element-binding protein , tonicity-responsive enhancer-binding protein

489734 Canis lupus familiaris
538523 Bos taurus
100067190 Equus caballus
100516737 Sus scrofa
334390 Danio rerio
415866 Gallus gallus
454203 Pan troglodytes
705518 Macaca mulatta
733294 Xenopus laevis
100173744 Pongo abelii
100474909 Ailuropoda melanoleuca
100495532 Xenopus (Silurana) tropicalis
100028106 Monodelphis domestica
100548405 Meleagris gallopavo
100561138 Anolis carolinensis
100603294 Nomascus leucogenys
54446 Mus musculus
10725 Homo sapiens
307820 Rattus norvegicus
Selected quality suppliers for NFAT5 Proteins (NFAT5)
Did you look for something else?