Browse our Ret Proto-Oncogene (RET) ELISA Kits

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Ret Proto-Oncogene ELISA Kits (RET)
On www.antibodies-online.com are 18 Ret Proto-Oncogene (RET) ELISA Kits from 9 different suppliers available. Additionally we are shipping Ret Proto-Oncogene Antibodies (386) and Ret Proto-Oncogene Proteins (38) and many more products for this protein. A total of 462 Ret Proto-Oncogene products are currently listed.
Synonyms:
c-Ret, CDHF12, CDHR16, cret, etID315074.13, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET, ret-A, RET-ELE1, ret1, RET9, RET51, wu:fd13h01, X-ret, xret
list all ELISA KIts Gene Name GeneID UniProt
RET 5979 P07949
RET 19713 P35546
RET 24716  

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Ret Proto-Oncogene (RET) ELISA Kits by Reactivity

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More ELISA Kits for Ret Proto-Oncogene Interaction Partners

Zebrafish Ret Proto-Oncogene (RET) interaction partners

  1. These data provide the first evidence for a physiologic role of these isoforms in RET pathway function.

  2. Significantly, we show that introduction of mapk10 (show MAPK10 ELISA Kits) mutations into ret heterozygotes enhanced the ENS deficit, supporting MAPK10 (show MAPK10 ELISA Kits) as a Hirschsprung disease (HSCR (show EDNRB ELISA Kits)) susceptibility locus. Our studies demonstrate that ret heterozygous zebrafish is a sensitized model, with many significant advantages over existing murine models, to explore the pathophysiology and complex genetics of HSCR (show EDNRB ELISA Kits).

  3. RET expression is investigated within the brain of zebrafish; both RET protein and mRNA are observed.

  4. In animals lacking Ret or Gfra3 (show GFRA3 ELISA Kits) function, myogenic gene expression is reduced in forming opercular muscles, but not in non-opercular muscles derived from the same muscle anlagen.

  5. evaluation of noncoding sequences at the zebrafish ret locus conserved among teleosts, and at the human RET locus, conserved among mammals

  6. genes beyond RET may be implicated in the genesis of sporadic cases of HD

Human Ret Proto-Oncogene (RET) interaction partners

  1. Up-regulation of RET expression is associated with medullary thyroid carcinoma.

  2. Eight rare RET-coding variants, one possible splice-site variant were identified in patients with Hirschsprung disease. Almost half of the identified rare variants are proven pathogenic in vitro.

  3. We also demonstrate that the effects of RET and NRG1 (show NRG1 ELISA Kits) are universal across European and Asian ancestries. In contrast, we detected a European-specific association of a low-frequency variant, rs80227144, in SEMA3. Conditional analyses on the lead SNPs revealed a secondary association signal, corresponding to an Asian-specific, low-frequency missense variant encoding RET p.Asp489Asn

  4. RET plays a role in mediating the phosphorylation of EGFR (show EGFR ELISA Kits) in head and neck squamous cell carcinoma. RET inhibition not only decreases tumor growth but also enhances the efficacy of EGFR (show EGFR ELISA Kits) inhibition with erlotinib treatment.

  5. Study identified TP53 (show TP53 ELISA Kits) and RET among the most mutated oncogenes in hepatocellular carcinoma to be associated with lower overall survival.

  6. A p.C634W mutation in ret proto-oncogene protein (RET) has been detected in a family affected with multiple endocrine neoplasia type 2A (MEN2A), in which most carriers have developed clinical symptoms.

  7. RET/papillary thyroid cancer (PTC (show F9 ELISA Kits)) rearrangements, resulting in aberrant activity of the RET protein tyrosine kinase (show EPHA8 ELISA Kits) receptor (show NTRK1 ELISA Kits), occur exclusively in papillary thyroid cancer. Serum thyroid stimulating hormone in RET/PTC-positive thyroid cancer patients without nodular goiter or Hashimoto's thyroiditis increased following surgery.

  8. RET aberrations were seen in 1.8% of diverse cancers, with most cases harboring actionable, albeit distinct, coexisting alterations

  9. RET is overexpressed in only a small subset of oral squamous cell carcinomas

  10. RET rs2435357 variant is a genetic risk for Hirschsprung disease in Indonesia.

Mouse (Murine) Ret Proto-Oncogene (RET) interaction partners

  1. we described a RET-ER81 (show ETV1 ELISA Kits)-Neuregulin1 signaling pathway in neurons innervating Pacinian corpuscle somatosensory end organs, which is essential for communication between the innervating axon and the end organ

  2. These data provide the first evidence for a physiologic role of these isoforms in RET pathway function.

  3. Hox (show MSH2 ELISA Kits) proteins coordinate motor neuron differentiation and connectivity programs through Ret/Gfra genes.

  4. Ret and Gfra2 (show GFRA2 ELISA Kits) null mice display comparable early central projection deficits, but Gfra2 (show GFRA2 ELISA Kits) null rapidly adapting mechanoreceptors recover later.

  5. Parkin (show PARK2 ELISA Kits) and the RET signaling cascade converge to control mitochondrial integrity and thereby properly maintain substantia nigra pars (show EPRS ELISA Kits) compacta dopaminergic neurons and their innervation in the striatum.

  6. the Ret signaling pathway is important for podocyte survival and recovery from glomerular injury in vivo

  7. RET coupling to ERK (show EPHB2 ELISA Kits) and Akt (show AKT1 ELISA Kits) depends strongly on artemin (show ARTN ELISA Kits) concentration, and it is highest at the low (~100 pM) artemin (show ARTN ELISA Kits) levels required for neurite outgrowth.

  8. we analysed non-thermal, atmospheric pressure, plasma irradiation mediated effects in melanocytic tumors which spontaneously developed in HL-RET-mice

  9. the important IL-10 (show IL10 ELISA Kits) transcription factor Maf (show MAF ELISA Kits) was upregulated in RET-deficient Th2 cells and down-regulated upon RET signalling activation by glial-derived neurotrophic factor (show NTF3 ELISA Kits) family ligands.

  10. the neurotrophic factor (show NTF3 ELISA Kits) receptor RET drives haematopoietic stem cell survival, expansion and function; haematopoietic stem cells express RET and its neurotrophic factor (show NTF3 ELISA Kits) partners are produced in the haematopoietic stem cell environment

Ret Proto-Oncogene (RET) Antigen Profile

Antigen Summary

This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed.

Alternative names and synonyms associated with Ret Proto-Oncogene (RET)

  • ret proto-oncogene receptor tyrosine kinase (ret) Elisa Kit
  • ret proto-oncogene (ret) Elisa Kit
  • ret proto-oncogene (RET) Elisa Kit
  • ret proto-oncogene (Ret) Elisa Kit
  • c-Ret Elisa Kit
  • CDHF12 Elisa Kit
  • CDHR16 Elisa Kit
  • cret Elisa Kit
  • etID315074.13 Elisa Kit
  • HSCR1 Elisa Kit
  • MEN2A Elisa Kit
  • MEN2B Elisa Kit
  • MTC1 Elisa Kit
  • PTC Elisa Kit
  • RET Elisa Kit
  • ret-A Elisa Kit
  • RET-ELE1 Elisa Kit
  • ret1 Elisa Kit
  • RET9 Elisa Kit
  • RET51 Elisa Kit
  • wu:fd13h01 Elisa Kit
  • X-ret Elisa Kit
  • xret Elisa Kit

Protein level used designations for Ret Proto-Oncogene (RET) ELISA Kits

proto-oncogene tyrosine-protein kinase receptor Ret , receptor tyrosine kinase , ret proto-oncogene , tryptase , proto-oncogene tyrosine-protein kinase receptor Ret-like , RET transforming sequence , cadherin family member 12 , cadherin-related family member 16 , hydroxyaryl-protein kinase , proto-oncogene c-Ret , ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease) , Ret gene for receptor tyrosin , Ret proto-oncogene (multiple endocrine neoplasia MEN2A MEN2B and medullary thyroid carcinoma 1 Hirschsprung disease) , ret tyrosine kinase

GENE ID SPECIES
30512 Danio rerio
373625 Xenopus laevis
449594 Pan troglodytes
703466 Macaca mulatta
100033966 Equus caballus
100403596 Callithrix jacchus
100442682 Pongo abelii
100467317 Ailuropoda melanoleuca
100495902 Xenopus (Silurana) tropicalis
100602103 Nomascus leucogenys
5979 Homo sapiens
19713 Mus musculus
24716 Rattus norvegicus
403494 Canis lupus familiaris
396107 Gallus gallus
515924 Bos taurus
100340710 Oryctolagus cuniculus
100733392 Cavia porcellus
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