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Browse our ROS1 Proteins (ROS1)

Full name:
C-Ros Oncogene 1 , Receptor tyrosine Kinase Proteins (ROS1)
On are 7 C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1) Proteins from 4 different suppliers available. Additionally we are shipping ROS1 Antibodies (185) and ROS1 Kits (6) and many more products for this protein. A total of 202 ROS1 products are currently listed.
c-ros, c-ros-1, MCF3, ROS, Ros-1, ROS1C
list all proteins Gene Name GeneID UniProt
ROS1 6098 P08922
ROS1 25346 Q63132
ROS1 19886 Q78DX7

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Human C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1) interaction partners

  1. 26 genes were found to fuse with ROS1 and different ROS1 fusions have distinct subcellular localization, suggesting that they may activate different substrates in vivo[review]

  2. ROS1-fusion genes act as a driver for the pathogenesis of lung adenocarcinoma.

  3. High prevalence of ROS1 copy number alterations are frequent in non-small cell lung cancer.

  4. our study suggested that the prevalence of ALK, ROS1 and RET (show RET Proteins) fusions is very rare in lung squamous cell carcinoma patients.

  5. curcumin and ABT-737 on HCC (show FAM126A Proteins) cells was investigated for the first time, to the best of our knowledge. It was found that curcumin markedly enhanced the antitumor effects of ABT-737 on HepG2 cells and activate ROS-ASK1 (show MAP3K5 Proteins)-c-Jun N-terminal kinase pathway .

  6. LIX1L is an RNA-binding protein, with implications for therapeutic approaches for targeting LIX1L in LIX1L-expressing cancer cells.

  7. ADAM9 (show ADAM9 Proteins) and ROS1 are direct downstream targets of miR (show MLXIP Proteins)-33a

  8. ALK and ROS1 rearrangements found in advanced non-small cell lung cancer patients

  9. Lung adenocarcinomas with RET and ROS1 fusions share many radiographic features.

  10. The upregulation of ROS1 and DDR1 was confirmed at the protein level by western blot. Treatment with a potent and specific pyrazole ROS1 inhibitor in ROS1 overexpressing clones led to a sensitization of these cells to low concentrations of gefitinib.

Mouse (Murine) C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1) interaction partners

  1. GPX1-dependent alterations in oxido-reductive stress promote ROS1 activation and mediate vascular remodeling.

  2. Foretinib is a potent inhibitor of oncogenic ROS1 fusion proteins.

  3. c-ros and its ligand may be necessary for differentiation of epithelia I and II in mouse.

ROS1 Protein Profile

Protein Summary

This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor.

Alternative names and synonyms associated with ROS1

  • c-ros oncogene 1 , receptor tyrosine kinase (ROS1)
  • c-ros oncogene 1 , receptor tyrosine kinase (Ros1)
  • Ros1 proto-oncogene (Ros1)
  • c-ros protein
  • c-ros-1 protein
  • MCF3 protein
  • ROS protein
  • Ros-1 protein
  • ROS1C protein

Protein level used designations for ROS1

c-Ros receptor tyrosine kinase , proto-oncogene c-Ros , proto-oncogene c-Ros-1 , proto-oncogene tyrosine-protein kinase ROS , receptor tyrosine kinase c-ros oncogene 1 , transmembrane tyrosine-specific protein kinase , v-ros UR2 sarcoma virus oncogene homolog 1 , v-ros avian UR2 sarcoma virus oncogene homolog 1 , Ros1 proto-oncogene , c-ros-1 , heart - derived c - ros - 1 proto - oncogene , proto-oncogene c-ros

6098 Homo sapiens
25346 Rattus norvegicus
396192 Gallus gallus
19886 Mus musculus
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