Browse our ROS1 Proteins (ROS1)

Full name:
C-Ros Oncogene 1 , Receptor tyrosine Kinase Proteins (ROS1)
On www.antibodies-online.com are 9 C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1) Proteins from 5 different suppliers available. Additionally we are shipping ROS1 Antibodies (186) and ROS1 Kits (6) and many more products for this protein. A total of 205 ROS1 products are currently listed.
Synonyms:
c-ros, c-ros-1, MCF3, ROS, Ros-1, ROS1C
list all proteins Gene Name GeneID UniProt
ROS1 6098 P08922
ROS1 25346 Q63132
ROS1 19886 Q78DX7

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Human C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1) interaction partners

  1. Female, cribriform structure and presence of psammoma body were the three most powerful indicator of ROS1 rearrangement status, and predictive formula was helpful in screening ROS1-rearranged non-small-cell lung carcinomas, especially for ROS1 immunochemistry equivocal cases.

  2. report adds the ZCCHC8-ROS1 fusion as oncogenic driver in GBM and supports the role of ROS1 activation in the pathogenesis of a subset of glioblastoma

  3. ROS1 mutation is associated with response to chemotherapy in lung adenocarcinoma.

  4. A subset of ALK-negative inflammatory myofibroblastic tumour (IMT) have rearrangement of ROS1, ETV6 (show ETV6 Proteins) or NTRK3 (show NTRK3 Proteins) as a possible oncogenic mechanism.

  5. This review highlights treatment options, including clinical trials for ROS1 rearrangement, RET fusions, NTRK1 fusions, MET exon skipping, BRAF mutations, and KRAS mutations.

  6. High CEP85L-ROS1 expression is associated with neoplasms.

  7. 26 genes were found to fuse with ROS1 and different ROS1 fusions have distinct subcellular localization, suggesting that they may activate different substrates in vivo[review]

  8. ROS1-fusion genes act as a driver for the pathogenesis of lung adenocarcinoma.

  9. High prevalence of ROS1 copy number alterations are frequent in non-small cell lung cancer.

  10. our study suggested that the prevalence of ALK, ROS1 and RET (show RET Proteins) fusions is very rare in lung squamous cell carcinoma patients.

Mouse (Murine) C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1) interaction partners

  1. GPX1-dependent alterations in oxido-reductive stress promote ROS1 activation and mediate vascular remodeling.

  2. Foretinib is a potent inhibitor of oncogenic ROS1 fusion proteins.

  3. c-ros and its ligand may be necessary for differentiation of epithelia I and II in mouse.

ROS1 Protein Profile

Protein Summary

This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor.

Alternative names and synonyms associated with ROS1

  • c-ros oncogene 1 , receptor tyrosine kinase (ROS1)
  • c-ros oncogene 1 , receptor tyrosine kinase (Ros1)
  • Ros1 proto-oncogene (Ros1)
  • c-ros protein
  • c-ros-1 protein
  • MCF3 protein
  • ROS protein
  • Ros-1 protein
  • ROS1C protein

Protein level used designations for ROS1

c-Ros receptor tyrosine kinase , proto-oncogene c-Ros , proto-oncogene c-Ros-1 , proto-oncogene tyrosine-protein kinase ROS , receptor tyrosine kinase c-ros oncogene 1 , transmembrane tyrosine-specific protein kinase , v-ros UR2 sarcoma virus oncogene homolog 1 , v-ros avian UR2 sarcoma virus oncogene homolog 1 , Ros1 proto-oncogene , c-ros-1 , heart - derived c - ros - 1 proto - oncogene , proto-oncogene c-ros

GENE ID SPECIES
6098 Homo sapiens
25346 Rattus norvegicus
396192 Gallus gallus
19886 Mus musculus
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