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Human WASF2 ELISA Kit for Sandwich ELISA - ABIN420384
Li, Luo, Xiao, Zhang, Qi, Liu, Zhang, Gao, Yang: Decreased expression of Wiskott-Aldrich syndrome protein family verprolin-homologous protein 2 may be involved in the development of pre-eclampsia. in Reproductive biomedicine online 2014
the MCP1 (show CCL2 ELISA Kits)-induced cortactin (show CTTN ELISA Kits) phosphorylation is dependent on PLCb3 (show PLCB3 ELISA Kits)-mediated PKC activation, and siRNA-mediated down-regulation of either of these molecules prevents cortactin (show CTTN ELISA Kits) interaction with WAVE2
WASp (show WASL ELISA Kits) and WAVE2 differ in their dynamics and their associated proteins
these results suggest that Arp2 (show ACTR2 ELISA Kits)/3 and the upstream regulator, WAVE2, are essential co-factors hijacked by HIV for intracellular migration, and may serve as novel targets to prevent HIV transmission.
WAVE2 is down-regulated in gastric cancer
Cortactin (show CTTN ELISA Kits) has a role as a scaffold for Arp2 (show ACTR2 ELISA Kits)/3 and WAVE2 at the epithelial zonula adherens
data reveal a critical role for WAVE2 complex in regulation of cellular signaling and epithelial morphogenesis
Identification of an onco-suppressive role of miR (show MLXIP ELISA Kits)-146a in gastric cancer cells by its reduction of WASF2 expression.
We demonstrate that WAVE2-Arp2 (show ACTR2 ELISA Kits)/3 is a major nucleator of actin assembly at the zonula adherens and likely acts in response to junctional Rac (show AKT1 ELISA Kits) signaling
results suggest that SKAP2 (show SKAP2 ELISA Kits) negatively regulates cell migration and tumor invasion in fibroblasts and glioblastoma cells by suppressing actin assembly induced by the WAVE2-cortactin (show CTTN ELISA Kits) complex
results indicate that by mediating intensive F-actin accumulation at the sites of cell infiltration, WAVE2, N-WASP (show WASL ELISA Kits), and Mena (show EGFR ELISA Kits) are crucial for PI3K (show PIK3CA ELISA Kits)-dependent cell invasion induced by PDGF (show PDGFA ELISA Kits)
The expression of NESH/Abi-3 (show ABI3 ELISA Kits) caused degradation of endogenous Abi-1 (show ABI1 ELISA Kits), which led to the formation of a NESH/Abi-3 (show ABI3 ELISA Kits)-based WAVE2 complex.
This study demonstrated that WAVE2-Abi2 complex, which controls growth cone activity, is crucial for completing transition from a multipolar to bipolar shape.
Results of the present study show that the nucleation-promoting factors JMY and WAVE2 are critical for cytokinesis during development of mouse embryos.
These results identify Wasf2 as a novel target of intermittent PTH administration via the Wnt and phosphoinositide-dependent protein kinase signaling pathways.
The protein and messenger RNA levels of WAVE2 were decreased in aged oocytes, but the levels were normal in caffeine-treated aged oocytes.
mDia1 and WAVE2 are important Src (show SRC ELISA Kits) homology 3 domain partners of IRSp53 (show BAIAP2 ELISA Kits) in forming filopodia.
WAVE2 regulates oocyte polarization by regulating meiotic spindle, peripheral positioning, probably via an actin-mediated pathway, and is involved in polar body emission during mouse oocyte meiotic maturation.
sential role for Abi1 (show ABI1 ELISA Kits) in embryonic survival and WAVE2 complex integrity
WAVE2 works as an A-kinase-anchoring protein (show MYRIP ELISA Kits) that recruits PKA at membrane protrusions and plays a role in the enlargement of membrane protrusions induced by PKA activation
Scar2 and the Arp2 (show AICDA ELISA Kits)/3 complex appear to be involved in the establishment and maintenance of Golgi polarity during directed migration
This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X. Two transcript variants encoding different isoforms have been found for this gene.
WAS protein family, member 2
, wiskott-Aldrich syndrome protein family member 2
, WASP family Verprolin-homologous protein 2
, WASP family protein member 2
, WASP family protein member 4
, protein WAVE-2
, putative Wiskott-Aldrich syndrome protein family member 4
, suppressor of cyclic-AMP receptor (WASP-family)
, verprolin homology domain-containing protein 2