Browse our WDR1 Proteins (WDR1)

Full name:
WD Repeat Domain 1 Proteins (WDR1)
On are 8 WD Repeat Domain 1 (WDR1) Proteins from 5 different suppliers available. Additionally we are shipping WDR1 Antibodies (41) and many more products for this protein. A total of 57 WDR1 products are currently listed.
Aip1, D5Wsu185e, NORI-1, rede
list all proteins Gene Name GeneID UniProt
WDR1 9948 O75083
Mouse WDR1 WDR1 22388 O88342
Rat WDR1 WDR1 360950 Q5RKI0

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WDR1 Proteins (WDR1) by Origin

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Top referenced WDR1 Proteins

  1. Human WDR1 Protein expressed in Escherichia coli (E. coli) - ABIN1047936 : Adler, Winnicki, Gong, Lomax: A gene upregulated in the acoustically damaged chick basilar papilla encodes a novel WD40 repeat protein. in Genomics 1999 (PubMed)

More Proteins for WDR1 Interaction Partners

Human WD Repeat Domain 1 (WDR1) interaction partners

  1. homozygous missense L153F/L293F mutation in the actin regulatory gene WDR1 causes a new autoinflammatory disease in humans, with periodic fevers, immunodeficiency, and intermittent thrombocytopenia (PFIT).

  2. These data suggest that WDR1 plays an important role in suppressing platelet activity, where it alters the actin cytoskeleton dynamics, and downregulation of WDR1 may contribute to the platelet-mediated pathogenesis of cardiovascular disease.

  3. Mutations in WDR1 affect neutrophil morphology, motility, and function, causing a novel primary immunodeficiency

  4. Identify positive correlations between WDR1 and CLNK (show CLNK Proteins) gene polymorphisms in Chinese-Tibetan gout populations.

  5. Demonstrate a previously unanticipated role of Aip1 (show BIRC3 Proteins) in regulating the structure and remodeling of intestinal epithelial junctions and early steps of epithelial morphogenesis.

  6. When maternal environmental tobacco smoke was considered, fifteen of 135 single nucleotide polymorphism (SNPs) mapping to SLC2A9 and 9 of 59 SNPs in WDR1 gave P values approaching genome-wide significance.

  7. Data suggest that anti-WD repeat domain 1 (WDR1) antibody could be applied for serological screening of papillary thyroid carcinoma (PTC (show F9 Proteins)) and undifferentiated thyroid carcinoma (UTC), and could be an efficient and inexpensive biomarker.

  8. WD repeat-containing protein 1 was confirmed as being significantly overexpressed in interstitial fluid from ovarian carcinomas compared to healthy ovarian tissue.

  9. Studies suggest that vascular endothelial growth factor may be responsible for upregulated P-glycoprotein expression.

  10. The QKI (show QKI Proteins) RNA-binding proteins regulate oligodendrocyte differentiation by modulating the expression of AIP-1 (show BIRC3 Proteins).

Mouse (Murine) WD Repeat Domain 1 (WDR1) interaction partners

  1. WDR1 interacts with Lim domain kinase 1 (LIMK1 (show LIMK1 Proteins)), a well known phosphorylation kinase of Cofilin (show CFL1 Proteins).

  2. Wdr1 and cofilin (show CFL1 Proteins)/destrin (show DSTN Proteins)-mediated actomyosin remodelling are essential for generating or maintaining cortical tension within the developing epidermal sheet and driving the cell shape and planar orientation changes.

  3. Wdr1-regulated actin dynamics play essential roles in heart function in mice. F-actin accumulations caused by Wdr1 deletion result in disruption of sarcomeric structure.

  4. The QKI (show QKI Proteins) RNA-binding proteins regulate oligodendrocyte differentiation by modulating the expression of AIP-1.

  5. studies establish an essential requirement for Wdr1 in megakaryocytes and neutrophils

WDR1 Protein Profile

Protein Summary

This gene encodes a protein containing 9 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, mostly including a trp-asp at the C-terminal end. WD domains are involved in protein-protein interactions. The encoded protein may help induce the disassembly of actin filaments. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with WDR1

  • WD repeat domain 1 (WDR1)
  • WD repeat domain 1 (Wdr1)
  • Aip1 protein
  • D5Wsu185e protein
  • NORI-1 protein
  • rede protein

Protein level used designations for WD Repeat Domain 1 Proteins (WDR1)

AIP1 , WD repeat-containing protein 1 , actin-interacting protein 1 , WD40 repeat protein 1 , WD repeat protein 1

422842 Gallus gallus
9948 Homo sapiens
533223 Bos taurus
22388 Mus musculus
360950 Rattus norvegicus
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