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Browse our anti-Wolfram Syndrome 1 (WFS1) Antibodies

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anti-Wolfram Syndrome 1 Antibodies (WFS1)
On are 38 Wolfram Syndrome 1 (WFS1) Antibodies from 11 different suppliers available. Additionally we are shipping Wolfram Syndrome 1 Kits (19) and Wolfram Syndrome 1 Proteins (4) and many more products for this protein. A total of 64 Wolfram Syndrome 1 products are currently listed.
AI481085, CG4917, Dmel\\CG4917, GB15257, WFRS, WFS, WFS1, WFSL, wolframin
list all antibodies Gene Name GeneID UniProt
WFS1 7466 O76024
WFS1 83725  
WFS1 22393 P56695

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Top referenced anti-Wolfram Syndrome 1 Antibodies

  1. Rat (Rattus) Polyclonal WFS1 Primary Antibody for IHC, WB - ABIN351414 : Inoue, Tanizawa, Wasson, Behn, Kalidas, Bernal-Mizrachi, Mueckler, Marshall, Donis-Keller, Crock, Rogers, Mikuni, Kumashiro, Higashi, Sobue, Oka, Permutt: A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome). in Nature genetics 1998 (PubMed)
    Show all 4 references for ABIN351414

More Antibodies against Wolfram Syndrome 1 Interaction Partners

Human Wolfram Syndrome 1 (WFS1) interaction partners

  1. Four novel mutations of the WFS1 gene in Iranian Wolfram syndrome pedigrees identified.

  2. Data show that Wolfram syndrome 1 (WFS1; wolframin) promoter activity was highest with the most frequent haplotype (H1; ATCGT) and lowest with second most frequent haplotype (H2; GATCG).

  3. Data suggest that a novel mutation in WFS1 [c.13481350 del ins (show INS Antibodies) TAG (p.His450*)] causes Wolfram-like syndrome in homozygous daughter with maternal uniparental disomy of chromosome 4; heterozygous mother is unaffected. [CASE REPORT]

  4. Micro-RNA Binding Site Polymorphisms in the WFS1 Gene Are Risk Factors of Diabetes Mellitus.

  5. The analysis of our case, in the light of the most recent literature, suggests a possible role for WFS1 gene in the development of certain brain structures during the fetal period.

  6. A novel missense mutation c.2389G > A (GAC (show GLS Antibodies) -AAC (show GLYAT Antibodies)) in WFS1 gene causes non-syndromic hearing loss in all, rather than in low or high, frequencies.

  7. Results reveal a role for WFS1 in the negative regulation of SERCA (show ATP2A3 Antibodies) and provide further insights into the function of WFS1 in calcium homeostasis.

  8. No association was found between wolframin gene H611R polymorphism and mood disorders.

  9. This study emphasizes the clinical and genetic heterogeneity in patients with WFS. Genotype-phenotype correlations may exist in patients with WFS1 mutations, as demonstrated by the disease onset.

  10. Early-onset Central diabetes insipidus is associated with de novo mutations of the AVP (show AVP Antibodies) gene and with hereditary WFS1 gene changes.

Mouse (Murine) Wolfram Syndrome 1 (WFS1) interaction partners

  1. WFS1-knockout mice develop a metabolic phenotype characterized with several physiological dysfunctions.

  2. RNA-sequencing of pancreatic islets from WFS1-deficient mice showed that Trpm5 (show TRPM5 Antibodies) is downregulated and the pathways related to tissue morphology, and endocrine system development/function/molecular transport network are influenced.

  3. Study demonstrates that Wfs1 deficiency in mice induces alterations in specific behavioural effects of ethanol like the increased anxiolytic-like and hypnotic action, but the decreased sedation

  4. Na-pump alpha1 -subunit mRNA was significantly decreased in the dorsal striatum and midbrain of Wfs1-deficient homozygous animals compared with wild-type littermates.

  5. Results reveal a role for WFS1 in the negative regulation of SERCA (show ATP2A3 Antibodies) and provide further insights into the function of WFS1 in calcium homeostasis.

  6. Energy metabolism and thyroid function of mice with deleted wolframin (Wfs1) gene.

  7. We show that the expression of Wfs1 starts during late embryonic development in the dorsal striatum and amygdala, then expands broadly at birth, possessing several transitory regions during maturation.

  8. Present results indicate that the effects of Wfs1-deficiency on behavioral rhythmicity are subtle suggesting that Wfs1 is not a major player in the neural networks responsible for circadian rhythmicity of behavior.

  9. Gene expression profiling was performed in Wfs1-deficient mice.

  10. Sex differences in the development of diabetes in mice with deleted wolframin (Wfs1) gene.

Wolfram Syndrome 1 (WFS1) Antigen Profile

Antigen Summary

This gene encodes a transmembrane protein, which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain, pancreas, heart, and insulinoma beta-cell lines. Mutations in this gene are associated with Wolfram syndrome, also called DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness), an autosomal recessive disorder. The disease affects the brain and central nervous system. Mutations in this gene can also cause autosomal dominant deafness 6 (DFNA6), also known as DFNA14 or DFNA38. Alternatively spliced transcript variants have been found for this gene.

Alternative names and synonyms associated with Wolfram Syndrome 1 (WFS1)

  • wolfram syndrome 1 (wfs1) antibody
  • wolfram syndrome 1 (CpipJ_CPIJ013087) antibody
  • wolframin (WFS1) antibody
  • Wolfram syndrome 1 (wolframin) (WFS1) antibody
  • Wolfram syndrome 1 (wolframin) (Wfs1) antibody
  • Wolfram syndrome 1 homolog (human) (Wfs1) antibody
  • AI481085 antibody
  • CG4917 antibody
  • Dmel\\CG4917 antibody
  • GB15257 antibody
  • WFRS antibody
  • WFS antibody
  • WFS1 antibody
  • WFSL antibody
  • wolframin antibody

Protein level used designations for WFS1

CG4917-PA , CG4917-PC , wfs1-PA , wfs1-PC , wolfram syndrome 1 , wolframin , Wolfram syndrome 1 , Wolfram syndrome 1 homolog , Wolfram syndrome 1 protein homolog

42679 Drosophila melanogaster
552818 Apis mellifera
6046150 Culex quinquefasciatus
100329063 Saccoglossus kowalevskii
7466 Homo sapiens
83725 Rattus norvegicus
482113 Canis lupus familiaris
100298456 Bos taurus
22393 Mus musculus
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