Browse our Thymidine Phosphorylase Proteins (TYMP)

On are 18 Thymidine Phosphorylase (TYMP) Proteins from 8 different suppliers available. Additionally we are shipping Thymidine Phosphorylase Antibodies (126) and Thymidine Phosphorylase Kits (35) and many more products for this protein. A total of 183 Thymidine Phosphorylase products are currently listed.
2900072D10Rik, CD363, CHEDG1, D1S3362, ECGF, Ecgf1, EDG-1, EDG1, hPD-ECGF, MEDPS1, MNGIE, MTDPS1, PD-ECGF, PDECGF, Pdgfec, S1P1, TP, typh
list all proteins Gene Name GeneID UniProt
TYMP 1901 P21453
TYMP 315219 Q5FVR2
TYMP 72962 Q99N42

Thymidine Phosphorylase Proteins (TYMP) by Origin

More Proteins for Thymidine Phosphorylase Interaction Partners

Human Thymidine Phosphorylase (TYMP) interaction partners

  1. Activated S1PR1 (show S1PR1 Proteins) signaling regulates the production of cellular adhesion molecules by inhibiting NF- kappaB (show NFKB1 Proteins) activation via a beta (show SUCLA2 Proteins)-arrestin2 (show ARRB2 Proteins)-dependent manner

  2. Studied the role of thymidine phosphorylase (TP) in promoting the invasion and metastasis of hepatocellular carcinoma (HCC (show FAM126A Proteins)). It was shown that TP correlated with MMP2 (show MMP2 Proteins) and MMP9 (show MMP9 Proteins) expression, and that TP mediated the migration of tumor cells through activity of MMPs in HCC (show FAM126A Proteins) cell lines.

  3. Model recombinant HDL (show HSD11B1 Proteins) (rHDL) particles formed in vitro with S1P (show MBTPS1 Proteins) incorporated into the particle initiated the internalization of S1PR1 (show S1PR1 Proteins), whereas rHDL without supplemented S1P (show MBTPS1 Proteins) did not, suggesting that S1P (show MBTPS1 Proteins) transported in HDL (show HSD11B1 Proteins) can selectively activate S1PR1 (show S1PR1 Proteins).

  4. Blocking of S1PR activity and inhibition of S1P (show MBTPS1 Proteins) synthesis led to decreased expression of fibrosis and tissue remodeling-related proteins in primary cultures of orbital fibroblasts derived from patients with GO.

  5. a lipid molecule repeatedly entered the receptor between the extracellular ends of TM1 (show TPM2 Proteins) and TM7, providing important insights into the pathway of ligand entry into the S1PR1 (show S1PR1 Proteins) .

  6. Mature human thymocytes rely on S1P (show MBTPS1 Proteins)-R1 to migrate toward S1P (show MBTPS1 Proteins). Taken in the context of murine work demonstrating that S1P (show MBTPS1 Proteins) is required for thymocyte egress to the periphery.

  7. ApoM (show APOM Proteins)-bound sphingosine-1-phosphate regulates adhesion molecule (show NCAM1 Proteins) abundance, leukocyte-endothelial adhesion, and endothelial barrier function via sphingosine-1-phosphate receptor1.

  8. The S1P1,3 activation results in Akt (show AKT1 Proteins) phosphorylation and subsequent activation of eNOS (show NOS3 Proteins) via phosphorylation at serine(1177) and dephosphorylation at threonine(495).

  9. HDL (show HSD11B1 Proteins)-associated ApoM (show APOM Proteins) is anti-apoptotic by delivering sphingosine 1-phosphate to S1P1 (show S1PR1 Proteins) and S1P3 (show S1PR3 Proteins) receptors on vascular endothelium.

  10. The present high prevalence of S1PR1 (show S1PR1 Proteins) overexpression warrants the consideration of testicular diffuse large B-cell lymphoma as a distinct disease subtype and suggests the potential of the S1P/S1PR1 (show S1PR1 Proteins) axis as a therapeutic target.

Mouse (Murine) Thymidine Phosphorylase (TYMP) interaction partners

  1. data identify TYMP as an astrocyte-derived permeability factor, and suggest TYMP and VEGFA (show VEGFA Proteins) together promote blood-brain barrier breakdown.

  2. TYMP participates in multiple platelet signaling pathways and regulates platelet activation and thrombosis. Targeting TYMP might be a novel antiplatelet and antithrombosis therapy.

  3. Thymidine phosphorylase and UPP1 (show UPP1 Proteins) double knockout mice showed increased thymidine and deoxyuridine in tissues and developed encephalopathy.

Thymidine Phosphorylase (TYMP) Protein Profile

Protein Summary

This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified.

Alternative names and synonyms associated with Thymidine Phosphorylase (TYMP)

  • thymidine phosphorylase (deoA)
  • thymidine phosphorylase (Dd586_0614)
  • thymidine phosphorylase (Kvar_4413)
  • thymidine phosphorylase (Nmag_4015)
  • thymidine phosphorylase (Snov_1187)
  • thymidine phosphorylase (Fbal_2856)
  • thymidine phosphorylase (Ftrac_2071)
  • thymidine phosphorylase (Intca_1216)
  • thymidine phosphorylase (Arcve_2095)
  • thymidine phosphorylase (Alide2_2726)
  • thymidine phosphorylase (Alide2_3372)
  • thymidine phosphorylase (Sphch_4174)
  • Thymidine phosphorylase (Sinme_3461)
  • thymidine phosphorylase (Metok_1244)
  • thymidine phosphorylase (Mesop_1831)
  • Thymidine phosphorylase (typh)
  • sphingosine-1-phosphate receptor 1 (S1PR1)
  • thymidine phosphorylase (TYMP)
  • thymidine phosphorylase (Tymp)
  • 2900072D10Rik protein
  • CD363 protein
  • CHEDG1 protein
  • D1S3362 protein
  • ECGF protein
  • Ecgf1 protein
  • EDG-1 protein
  • EDG1 protein
  • hPD-ECGF protein
  • MEDPS1 protein
  • MNGIE protein
  • MTDPS1 protein
  • PD-ECGF protein
  • PDECGF protein
  • Pdgfec protein
  • S1P1 protein
  • TP protein
  • typh protein

Protein level used designations for Thymidine Phosphorylase Proteins (TYMP)

thymidine phosphorylase , Thymidine phosphorylase , S1P receptor 1 , S1P receptor Edg-1 , endothelial differentiation G-protein coupled receptor 1 , endothelial differentiation, sphingolipid G-protein-coupled receptor, 1 , sphingosine 1-phosphate receptor 1 , sphingosine 1-phosphate receptor EDG1 , sphingosine 1-phosphate receptor Edg-1 , gliostatin , tdRPase , TP , endothelial cell growth factor 1 (platelet-derived) , platelet derived growth factor, endothelial cell

1169045 Shewanella oneidensis MR-1
3195037 Ruegeria pomeroyi DSS-3
8659528 Dickeya dadantii Ech586
8784599 Klebsiella variicola At-22
8828749 Natrialba magadii ATCC 43099
9332248 Starkeya novella DSM 506
9771698 Ferrimonas balearica DSM 9799
10012217 Marivirga tractuosa DSM 4126
10084015 Intrasporangium calvum DSM 43043
10395229 Archaeoglobus veneficus SNP6
10483774 Alicycliphilus denitrificans K601
10484428 Alicycliphilus denitrificans K601
10724533 Sphingobium chlorophenolicum L-1
10728080 Sinorhizobium meliloti AK83
10773400 Methanothermococcus okinawensis IH1
10825661 Mesorhizobium opportunistum WSM2075
100195250 Salmo salar
1901 Homo sapiens
1890 Homo sapiens
315219 Rattus norvegicus
72962 Mus musculus
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