Browse our Parvin alpha Proteins (PARVA)

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Parvin, alpha Proteins (PARVA)
On are 11 Parvin, alpha (PARVA) Proteins from 7 different suppliers available. Additionally we are shipping Parvin alpha Antibodies (93) and many more products for this protein. A total of 109 Parvin alpha products are currently listed.
2010012A22Rik, 5430400F08Rik, Actp, AI225929, AU042898, CH-ILKBP, MXRA2, Parva, Parvin, wu:fc59e06, zgc:101643
list all proteins Gene Name GeneID UniProt
PARVA 55742 Q9NVD7
PARVA 57342 Q9EPC1
PARVA 57341 Q9HB97

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Parvin alpha Proteins (PARVA) by Origin

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Top referenced Parvin alpha Proteins

  1. Human Parvin alpha Protein expressed in Escherichia coli (E. coli) - ABIN1098425 : Nikolopoulos, Turner: Actopaxin, a new focal adhesion protein that binds paxillin LD motifs and actin and regulates cell adhesion. in The Journal of cell biology 2001 (PubMed)
    Show all 2 references for 1098425

More Proteins for Parvin alpha Interaction Partners

Human Parvin, alpha (PARVA) interaction partners

  1. Protein expression of alpha-Parvin increases with colorectal cancer progression.

  2. PARVA promotes metastasis by modulating ILK (show ILK Proteins) signalling pathway in lung adenocarcinoma

  3. alpha-Parvin, a pseudopodial constituent, was found to promote migration of breast cancer cells and to be expressed exclusively by Invasive lobular carcinoma

  4. Actopaxin plays a role in hepatocellular carcinoma progression and metastasis, by way of regulation of cell invasiveness and motility, an epithelial-mesenchymal transition process, and chemosensitivity to cytotoxic drugs.

  5. beta2-adaptin (show AP2B1 Proteins) is shown to bind to the focal adhesion protein actopaxin and localize to focal adhesions during cells spreading in an actopaxin dependent manner

  6. alpha-parvin, beta-parvin (show PARVB Proteins) and migfilin (show FBLIM1 Proteins) were expressed in tumor cells in 53%, 2%, 28% and 53% of effusions and 57%, 20%, 83% and 25% of solid lesions, respectively.

  7. Actopaxin phosphorylation is required for matrix degradation and cell invasion via regulation of Rho GTPase (show RACGAP1 Proteins) signaling.

  8. results also identify the integrin-linked kinase (ILK (show ILK Proteins)) and alpha-parvin proteins as a new molecular partner and target, respectively, of the Lnk (show SH2B3 Proteins) adaptor.

  9. the alpha-parvin CH2 (show Acyp1 Proteins)-paxillin (show PXN Proteins) LD1 complex has a role in focal adhesion assembly

  10. inhibition of the ILK (show ILK Proteins)-alpha-parvin complex is sufficient, although not necessary, for promotion of apoptosis

Mouse (Murine) Parvin, alpha (PARVA) interaction partners

  1. this study has identified a new role for Parvin and alphaPix (show ARHGEF6 Proteins) downstream of the integrin-ILK (show ILK Proteins) signaling axis for mammary epithelial cell differentiation.

  2. These results provide important evidence for a crucial role of the PINCH-1 (show LIMS1 Proteins)-ILK (show ILK Proteins)-alpha-parvin complex in the control of podocyte adhesion, morphology, and survival.

  3. Results describe the roles of the ILK (show ILK Proteins)-PINCH (show LIMS1 Proteins)-parvin triad proteins in the maturation of focal adhesions.

  4. Findings show that alpha-pv represents an essential adhesion checkpoint that controls RhoA (show RHOA Proteins)/ROCK-mediated contractility in vSMCs.

Parvin alpha (PARVA) Protein Profile

Protein Summary

This gene encodes a member of the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. The encoded protein is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, motility and survival.

Alternative names and synonyms associated with Parvin alpha (PARVA)

  • parvin, alpha (PARVA)
  • parvin, alpha a (parvaa)
  • parvin, alpha (Parva)
  • parvin, alpha (parva)
  • 2010012A22Rik protein
  • 5430400F08Rik protein
  • Actp protein
  • AI225929 protein
  • AU042898 protein
  • CH-ILKBP protein
  • MXRA2 protein
  • Parva protein
  • Parvin protein
  • wu:fc59e06 protein
  • zgc:101643 protein

Protein level used designations for Parvin, alpha Proteins (PARVA)

parvin, alpha , alpha-parvin , parvin , alpha-parvin-like , actopaxin , calponin-like integrin-linked kinase-binding protein , matrix-remodeling-associated protein 2

423030 Gallus gallus
442922 Danio rerio
476859 Canis lupus familiaris
615430 Bos taurus
748437 Pan troglodytes
100159208 Acyrthosiphon pisum
100331103 Danio rerio
100466429 Ailuropoda melanoleuca
100541817 Meleagris gallopavo
55742 Homo sapiens
57342 Mus musculus
57341 Rattus norvegicus
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