Browse our BMPR1A Proteins (BMPR1A)

Full name:
Bone Morphogenetic Protein Receptor, Type IA Proteins (BMPR1A)
On are 2 Bone Morphogenetic Protein Receptor, Type IA (BMPR1A) Proteins from 1 different suppliers available. Additionally we are shipping BMPR1A Antibodies (14) and and many more products for this protein. A total of 18 BMPR1A products are currently listed.
10q23del, ACVRLK3, ALK3, BMPR1A, CD292, SKR5
list all proteins Gene Name GeneID UniProt
BMPR1A 657 P36894

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Human Bone Morphogenetic Protein Receptor, Type IA (BMPR1A) interaction partners

  1. The present study suggests that HNF-4alpha (show HNF4A Proteins) has a suppressive effect on hepcidin (show HAMP Proteins) expression by inactivating the BMP pathway, specifically via BMPR1A, in HepG2 cells.

  2. In solid ameloblastoma, positive correlations were observed between the stromal and parenchymal expression of BMP-2 (show BMP2 Proteins) and between the stromal expression of BMP-2 (show BMP2 Proteins) and BMP-4 (show BMP4 Proteins), as well as between the stromal expression of BMPR-II (show BMPR2 Proteins) and BMP-4 (show BMP4 Proteins) and the stromal and parenchymal expression of BMPR-II (show BMPR2 Proteins).

  3. Data show that protein kinase (show CDK7 Proteins) LKB1 (show STK11 Proteins) physically interacts with BMP type I receptors and requires Smad7 (show SMAD7 Proteins) protein to promote downregulation of the receptor.

  4. BMPR1A(+) ASCs show an enhanced ability for adipogenesis in vitro, as shown by gene expression and histological staining.

  5. Duplication of 10q22.3-q23.3 encompassing BMPR1A gene is associated with congenital heart disease, microcephaly, and mild intellectual disability

  6. Authors analyzed human databases from TCGA and survival data from microarrays to confirm BMPR1a tumor promoting functions, and found that high BMPR1a gene expression correlates with decreased survival regardless of molecular breast cancer subtype.

  7. About half of BMPR1A-related polyps displayed loss of heterozygosity, predominantly in the epithelial compartment, compatible with BMPR1A acting as a tumour suppressor gene.

  8. Results support a novel role for miR (show MLXIP Proteins)-885-3p in tumor angiogenesis by targeting BMPR1A, which regulates a proangiogenic factor.

  9. Decreased expression of BMPR1A was associated malignant gallbladder lesions.

  10. High BMPR1A expression is associated with glioma tumorigenesis.

BMPR1A Protein Profile

Protein Summary

The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

Alternative names and synonyms associated with BMPR1A

  • bone morphogenetic protein receptor, type IA (BMPR1A)
  • bone morphogenetic protein receptor, type IA (LOC100223148)
  • bone morphogenetic protein receptor, type IA (bmpr1a)
  • 10q23del protein
  • ACVRLK3 protein
  • ALK3 protein
  • BMPR1A protein
  • CD292 protein
  • SKR5 protein

Protein level used designations for BMPR1A

ALK-3 , BMP type-1A receptor , BMPR-1A , activin A receptor, type II-like kinase 3 , activin receptor-like kinase 3 , bone morphogenetic protein receptor type-1A , serine/threonine-protein kinase receptor R5 , bone morphogenetic protein receptor, type IA , bone morphogenetic protein receptor type-1A-like

657 Homo sapiens
696898 Macaca mulatta
100064367 Equus caballus
100077843 Ornithorhynchus anatinus
100153524 Sus scrofa
450572 Pan troglodytes
100026839 Monodelphis domestica
100223148 Taeniopygia guttata
100350518 Oryctolagus cuniculus
100402757 Callithrix jacchus
100450136 Pongo abelii
100472999 Ailuropoda melanoleuca
100561841 Anolis carolinensis
100583682 Nomascus leucogenys
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